Explain how the sequence of bases in a gene impacts protein structure.
Understand the Problem
The question is asking how the specific order of nucleotide bases in a gene determines the structure of the corresponding protein. This relates to the relationship between DNA sequence, mRNA transcription, and protein translation, affecting amino acid sequence and ultimately protein folding and function.
Answer
The base sequence in a gene dictates the amino acid sequence of a protein, influencing its shape and function.
The sequence of bases in a gene determines the sequence of amino acids in a protein through codons, which are triplets of nucleotide bases each coding for a specific amino acid. This sequence dictates the protein's primary structure, impacting its final three-dimensional shape and function.
Answer for screen readers
The sequence of bases in a gene determines the sequence of amino acids in a protein through codons, which are triplets of nucleotide bases each coding for a specific amino acid. This sequence dictates the protein's primary structure, impacting its final three-dimensional shape and function.
More Information
The sequence of bases in DNA is transcribed into mRNA, which is then translated into proteins. The exact sequence affects the protein's folding, influencing its biological activity. Mutations can alter this sequence, leading to changes in protein function or disease.
Tips
A common mistake is not considering how changes in even a single nucleotide can lead to significant impacts on the protein function due to alterations in amino acid sequence.
Sources
- DNA, RNA and Protein Synthesis - learn.genetics.utah.edu
- Protein structure: Primary, secondary, tertiary & quaternary - khanacademy.org
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