Do osmotic diuretics like mannitol act on receptors to promote increased urine formation?
Understand the Problem
The question is asking whether osmotic diuretics like mannitol act on receptors to increase urine formation. This requires knowledge of how osmotic diuretics function.
Answer
Osmotic diuretics like mannitol do not act on receptors. They increase urine production by increasing the osmolality of the glomerular filtrate.
Osmotic diuretics, like mannitol, do not act on receptors. They increase the osmolality of the glomerular filtrate, drawing water into the filtrate and increasing urine production.
Answer for screen readers
Osmotic diuretics, like mannitol, do not act on receptors. They increase the osmolality of the glomerular filtrate, drawing water into the filtrate and increasing urine production.
More Information
Mannitol is freely filtered in the kidneys but poorly reabsorbed, leading to its osmotic diuretic effect.
Tips
A common mistake is thinking all diuretics work through receptor interactions. Osmotic diuretics are an exception.
Sources
- Osmotic Diuretic - an overview | ScienceDirect Topics - sciencedirect.com
- Osmotic Diuretic - an overview | ScienceDirect Topics - sciencedirect.com
- Mannitol: Uses, Interactions, Mechanism of Action | DrugBank Online - go.drugbank.com
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