Associate the long-term complications with the pathophysiological mechanism: Retinopathy | Sorbitol accumulation in retinal cells Peripheral Neuropathy | Increased vascular permea... Associate the long-term complications with the pathophysiological mechanism: Retinopathy | Sorbitol accumulation in retinal cells Peripheral Neuropathy | Increased vascular permeability Diabetic Nephropathy | Glucosuria leading to glomerular sclerosis Advanced Glycation End Products (AGEs) | Sorbitol accumulation in Schwann cells
Understand the Problem
The question is asking to match the long-term complications of diabetes with their corresponding pathophysiological mechanisms. It presents four complications—Retinopathy, Peripheral Neuropathy, Diabetic Nephropathy, and Advanced Glycation End Products (AGEs)—each paired with a potential mechanism. The task is to associate each complication with the correct underlying cause.
Answer
* **Retinopathy:** Increased vascular permeability * **Peripheral Neuropathy:** Sorbitol accumulation in Schwann cells * **Diabetic Nephropathy:** Glucosuria leading to glomerular sclerosis * **Advanced Glycation End Products (AGEs):** Sorbitol accumulation in retinal cells
Here's how the long-term complications associate with the pathophysiological mechanisms:
- Retinopathy: Increased vascular permeability
- Peripheral Neuropathy: Sorbitol accumulation in Schwann cells
- Diabetic Nephropathy: Glucosuria leading to glomerular sclerosis
- Advanced Glycation End Products (AGEs): Sorbitol accumulation in retinal cells
Answer for screen readers
Here's how the long-term complications associate with the pathophysiological mechanisms:
- Retinopathy: Increased vascular permeability
- Peripheral Neuropathy: Sorbitol accumulation in Schwann cells
- Diabetic Nephropathy: Glucosuria leading to glomerular sclerosis
- Advanced Glycation End Products (AGEs): Sorbitol accumulation in retinal cells
More Information
Diabetic complications are mainly categorized as microvascular complications, such as diabetic retinopathy, nephropathy, and neuropathy, result from damage to small blood vessels and can lead to organ and.
Tips
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Sources
- Advanced Glycation End Products and Diabetic Complications - PMC - pmc.ncbi.nlm.nih.gov
- Advanced Glycation End Products and Their Effect on Vascular ... - pmc.ncbi.nlm.nih.gov
- Management of Microcomplications of Diabetes Mellitus - MDPI - mdpi.com
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