Analysis the figures, which pathway does Bavachinin work on?
Understand the Problem
The question is asking to analyze the provided figures to determine the pathway that Bavachinin affects. This likely involves interpreting various data from biological assays presented in the figures, focusing on the results related to different control and treatment conditions.
Answer
AKT/mTOR/SREBP-2 and p38 MAPK pathways.
Bavachinin works on pathways including AKT/mTOR/SREBP-2 and p38 MAPK-mediated pathways.
Answer for screen readers
Bavachinin works on pathways including AKT/mTOR/SREBP-2 and p38 MAPK-mediated pathways.
More Information
Bavachinin is known to interfere with cholesterol synthesis through the AKT/mTOR/SREBP-2 pathway and induce cell cycle arrest through the p38 MAPK pathway.
Tips
Always compare treated vs control samples to identify significant pathway activations.
Sources
- Bavachinin inhibits cholesterol synthesis enzyme FDFT1 expression ... - sciencedirect.com
- Induction of G2/M Cell Cycle Arrest via p38/p21Waf1/Cip1 ... - pmc.ncbi.nlm.nih.gov
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