Podcast
Questions and Answers
Which of the following is a challenge associated with the development of subunit vaccines?
Which of the following is a challenge associated with the development of subunit vaccines?
- Weak immune responses without boosting
- Limited efficacy against viral variants
- Difficulty in culturing the virus
- Expensive production process (correct)
What is the key technical challenge associated with mRNA vaccines?
What is the key technical challenge associated with mRNA vaccines?
- Delivering the mRNA to host cells
- Preventing degradation of mRNA (correct)
- Modifying nucleosides
- Generating the viral spike protein
Which virus is used as a live-attenuated vaccine or a non-replicating viral vaccine in some viral vector-based vaccines?
Which virus is used as a live-attenuated vaccine or a non-replicating viral vaccine in some viral vector-based vaccines?
- Simian adenovirus (correct)
- Hepatitis B virus
- Plasmodium falciparum
- Human papilloma virus
What is the main advantage of mRNA vaccines compared to other vaccine types?
What is the main advantage of mRNA vaccines compared to other vaccine types?
Which of the following is NOT a characteristic of subunit vaccines?
Which of the following is NOT a characteristic of subunit vaccines?
What is the purpose of adjuvants in vaccination?
What is the purpose of adjuvants in vaccination?
Which of the following is a general principle of vaccination?
Which of the following is a general principle of vaccination?
What is the purpose of adjuvants in vaccines?
What is the purpose of adjuvants in vaccines?
Which type of vaccine works by generating a long-lasting, high-affinity IgG antibody response?
Which type of vaccine works by generating a long-lasting, high-affinity IgG antibody response?
What is the main advantage of live vaccines?
What is the main advantage of live vaccines?
Which vaccine is 95% effective at preventing chickenpox?
Which vaccine is 95% effective at preventing chickenpox?
Why is the Varicella-Zoster vaccine not on the UK schedule at present?
Why is the Varicella-Zoster vaccine not on the UK schedule at present?
Which of the following is the correct definition of immunisation?
Which of the following is the correct definition of immunisation?
Which of the following is an example of passive immunisation?
Which of the following is an example of passive immunisation?
What did Edward Jenner use to protect against smallpox infection in 1796?
What did Edward Jenner use to protect against smallpox infection in 1796?
Which of the following is true about passive vaccines?
Which of the following is true about passive vaccines?
What is the purpose of adjuvants and vaccine conjugation in vaccination?
What is the purpose of adjuvants and vaccine conjugation in vaccination?
What is the estimated reduction in mortality worldwide due to immunisation?
What is the estimated reduction in mortality worldwide due to immunisation?
Which of the following is true about zoster vaccination?
Which of the following is true about zoster vaccination?
Which type of polio vaccine is better suited for endemic areas?
Which type of polio vaccine is better suited for endemic areas?
What is the mode of spread of enterovirus during polio infection?
What is the mode of spread of enterovirus during polio infection?
What is the percentage of patients who develop the neurological phase of polio?
What is the percentage of patients who develop the neurological phase of polio?
What happens during the primary infection of tuberculosis?
What happens during the primary infection of tuberculosis?
What is the effect of aging on zoster incidence?
What is the effect of aging on zoster incidence?
Which of the following is true about TB vaccination?
Which of the following is true about TB vaccination?
Which of the following is a characteristic of killed vaccines?
Which of the following is a characteristic of killed vaccines?
Which of the following is true about influenza vaccines?
Which of the following is true about influenza vaccines?
Subunit vaccines rely on which type of immune response for protection?
Subunit vaccines rely on which type of immune response for protection?
Which of the following is true about adjuvants in subunit vaccines?
Which of the following is true about adjuvants in subunit vaccines?
What is the purpose of vaccine conjugation in polysaccharide vaccines?
What is the purpose of vaccine conjugation in polysaccharide vaccines?
Which term refers to the artificial process by which someone is rendered immune?
Which term refers to the artificial process by which someone is rendered immune?
What is the purpose of adjuvants in vaccines?
What is the purpose of adjuvants in vaccines?
What is the main focus of this lecture on vaccines?
What is the main focus of this lecture on vaccines?
What is the percentage increase in the length of the lecture on vaccines compared to a few years ago?
What is the percentage increase in the length of the lecture on vaccines compared to a few years ago?
Which type of vaccine contains the whole intact organism, but may be live or inactivated?
Which type of vaccine contains the whole intact organism, but may be live or inactivated?
What is the purpose of adjuvants in vaccination?
What is the purpose of adjuvants in vaccination?
Which of the following diseases are difficult to prevent and clear through vaccination due to the limitations of our immune response?
Which of the following diseases are difficult to prevent and clear through vaccination due to the limitations of our immune response?
Which type of vaccine works by generating a long-lasting, high-affinity IgG antibody response?
Which type of vaccine works by generating a long-lasting, high-affinity IgG antibody response?
Which of the following is true about live attenuated vaccines?
Which of the following is true about live attenuated vaccines?
Which of the following is a disadvantage of live attenuated vaccines?
Which of the following is a disadvantage of live attenuated vaccines?
Which type of immune response can live attenuated vaccines achieve?
Which type of immune response can live attenuated vaccines achieve?
Which of the following is true about subunit vaccines?
Which of the following is true about subunit vaccines?
Which term is used interchangeably with vaccination?
Which term is used interchangeably with vaccination?
What is the main difference between vaccination and immunisation?
What is the main difference between vaccination and immunisation?
What was the source of fluid used for variolation during ancient times?
What was the source of fluid used for variolation during ancient times?
What is the main advantage of passive immunisation?
What is the main advantage of passive immunisation?
Which of the following is true about the Sabin oral polio vaccine?
Which of the following is true about the Sabin oral polio vaccine?
What is the main advantage of the Salk polio vaccine compared to the Sabin vaccine?
What is the main advantage of the Salk polio vaccine compared to the Sabin vaccine?
What is the golden focus in tuberculosis?
What is the golden focus in tuberculosis?
What is the purpose of the BCG vaccine?
What is the purpose of the BCG vaccine?
Which of the following is true about the varicella zoster vaccine?
Which of the following is true about the varicella zoster vaccine?
Which of the following is a concern associated with the varicella zoster vaccine?
Which of the following is a concern associated with the varicella zoster vaccine?
What is the purpose of the zoster vaccine in older adults?
What is the purpose of the zoster vaccine in older adults?
What is the mode of spread of polio during infection?
What is the mode of spread of polio during infection?
Which of the following is the most common method used to kill organisms in vaccines?
Which of the following is the most common method used to kill organisms in vaccines?
Which type of cells are stimulated by killed vaccines?
Which type of cells are stimulated by killed vaccines?
Which vaccines are mentioned as examples of killed vaccines in the text?
Which vaccines are mentioned as examples of killed vaccines in the text?
Which type of influenza vaccine is licensed for children in the UK?
Which type of influenza vaccine is licensed for children in the UK?
What is the main advantage of live vaccines compared to killed vaccines?
What is the main advantage of live vaccines compared to killed vaccines?
Which group of individuals can receive live vaccines?
Which group of individuals can receive live vaccines?
