Podcast
Questions and Answers
What class is Zidovudine (Retrovir)?
What class is Zidovudine (Retrovir)?
- NNRTI (Non-Nucleoside Reverse Transcriptase Inhibitor)
- Entry Inhibitor
- NRTI (Nucleoside Reverse Transcriptase Inhibitor) (correct)
- Protease Inhibitor
When do you give Zidovudine (Retrovir)? (Select all that apply)
When do you give Zidovudine (Retrovir)? (Select all that apply)
- HIV infection (correct)
- To reduce perinatal transmission from mother to baby in utero (correct)
- For treating viral pneumonia
- Post exposure prophylaxis (correct)
What is the mechanism of action of Zidovudine (Retrovir)?
What is the mechanism of action of Zidovudine (Retrovir)?
Uses zidovudine instead of thymidine, terminating the growing chain and creating a defective DNA strand.
What are common adverse effects of Zidovudine (Retrovir)? (Select all that apply)
What are common adverse effects of Zidovudine (Retrovir)? (Select all that apply)
What are other adverse effects of Zidovudine (Retrovir)? (Select all that apply)
What are other adverse effects of Zidovudine (Retrovir)? (Select all that apply)
What are the serious adverse effects of Zidovudine (Retrovir)? (Select all that apply)
What are the serious adverse effects of Zidovudine (Retrovir)? (Select all that apply)
What are contraindications of Zidovudine (Retrovir)?
What are contraindications of Zidovudine (Retrovir)?
What can combining Zidovudine (Retrovir) with other antiretroviral drugs contribute to?
What can combining Zidovudine (Retrovir) with other antiretroviral drugs contribute to?
What are nursing implications for Zidovudine (Retrovir)?
What are nursing implications for Zidovudine (Retrovir)?
Flashcards
What type of drug is Zidovudine (Retrovir)?
What type of drug is Zidovudine (Retrovir)?
A type of antiretroviral drug that inhibits the activity of reverse transcriptase, an enzyme used by HIV to replicate.
When is Zidovudine (Retrovir) used?
When is Zidovudine (Retrovir) used?
Zidovudine is used to treat HIV infection.
How does Zidovudine (Retrovir) work?
How does Zidovudine (Retrovir) work?
Zidovudine interferes with the HIV virus's ability to produce copies of itself by incorporating a faulty building block into the viral DNA.
What is a common side effect of Zidovudine (Retrovir)?
What is a common side effect of Zidovudine (Retrovir)?
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What are other side effects of Zidovudine (Retrovir)?
What are other side effects of Zidovudine (Retrovir)?
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What are serious side effects of Zidovudine (Retrovir)?
What are serious side effects of Zidovudine (Retrovir)?
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Who should not take Zidovudine (Retrovir)?
Who should not take Zidovudine (Retrovir)?
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What can happen when Zidovudine (Retrovir) is combined with other antiretrovirals?
What can happen when Zidovudine (Retrovir) is combined with other antiretrovirals?
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What are important nursing considerations for Zidovudine (Retrovir)?
What are important nursing considerations for Zidovudine (Retrovir)?
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Study Notes
Zidovudine (Retrovir) Overview
- Zidovudine is classified as an NRTI (nucleoside reverse transcriptase inhibitor), essential in antiretroviral therapy.
Administration Uses
- Prescribed for treating HIV infection.
- Used in post-exposure prophylaxis for HIV.
- Administered to reduce perinatal transmission from mother to child during pregnancy.
Mechanism of Action
- Works by replacing thymidine with zidovudine, leading to the termination of the growing viral DNA strand and the production of defective DNA.
Common Adverse Effects
- Notable adverse effects include anemia and neutropenia, which require monitoring.
Additional Adverse Effects
- Other side effects can include nausea, anorexia, diarrhea, fatigue, myalgia, and headaches.
Serious Adverse Effects
- May cause severe toxicity to bone marrow, central nervous system effects, and potentially fatal lactic acidosis.
Contraindications
- Contraindicated in patients with preexisting anemia, neutropenia, renal or hepatic impairment, patients on drugs that suppress bone marrow function, and those using St. John's Wort.
Drug Interactions
- Combining Zidovudine with other antiretroviral medications can increase the risk of lactic acidosis and hepatomegaly.
Nursing Implications
- Monitor lab results, watch for adverse reactions, manage opportunistic infections, and ensure patient adherence to therapy.
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Description
Test your knowledge on Zidovudine (Retrovir) with these flashcards. Covering its class, usage in HIV treatment, and mechanism of action, this quiz is perfect for students or healthcare professionals looking to enhance their understanding of this essential antiretroviral medication.
