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Questions and Answers

A patient is prescribed metronidazole for H. pylori infection. Which instruction is most important to provide regarding potential adverse effects and interactions?

  • "Avoid consuming any dairy products while taking this medication."
  • "Refrain from alcohol consumption during and for several days after completing the therapy." (correct)
  • "Monitor for increased urine output, as this medication can have diuretic effects."
  • "Take this medication on an empty stomach to enhance absorption."

A patient with renal impairment is prescribed clarithromycin for H. pylori eradication. What specific monitoring is most important?

  • Monitor for signs of peripheral neuropathy.
  • Assess for changes in visual acuity.
  • Closely monitor blood urea nitrogen (BUN) levels. (correct)
  • Regularly assess liver enzyme levels.

A patient is prescribed tetracycline for H. pylori infection. Which instructions are important to ensure proper drug administration and minimize adverse effects?

  • "Take this medication at the same time each day with a magnesium-containing antacid to help with absorption, and limit fluid intake during the course."
  • "Take this medication with grapefruit juice to enhance its effectiveness, and monitor for any signs of increased bruising or bleeding."
  • "Take this medication one hour before or two hours after meals, avoiding dairy products, and protect yourself from direct sunlight exposure." (correct)
  • "Take this medication with food to minimize gastrointestinal upset, and ensure you finish the entire course of antibiotics, even if you feel better."

Misoprostol is prescribed for a patient taking NSAIDs to protect against gastric ulcers. Which instruction should the nurse emphasize?

<p>&quot;This medication helps protect your stomach lining from the damaging effects of NSAIDs.&quot; (B)</p> Signup and view all the answers

What factor is most closely associated with the declining rates of gastric cancer?

<p>Increased awareness and testing for <em>H. pylori</em> infections. (B)</p> Signup and view all the answers

A patient with a family history of gastric cancer is concerned about their risk. Which dietary modification would be most beneficial in reducing their risk, based on the provided information?

<p>Consuming a diet rich in fruits and vegetables while limiting pickled and processed foods. (D)</p> Signup and view all the answers

A patient presents with fatigue, unintentional weight loss, and iron deficiency anemia. An EGD reveals a gastric tumor. Which of the following is the most likely next step in diagnosing the extent of the disease?

<p>Scheduling a CT scan of the chest, abdomen, and pelvis. (C)</p> Signup and view all the answers

Following an EGD with biopsy, a patient reports sudden, severe abdominal pain, chest pain, and abdominal distention. What is the most immediate concern?

<p>Perforation of the gastrointestinal tract. (A)</p> Signup and view all the answers

A patient undergoing an EGD is found to have a gastric polyp. Further testing reveals an H. pylori infection. What is the significance of identifying and treating the H. pylori infection in this patient?

<p>It reduces the risk of chronic gastritis and potential gastric cancer development. (D)</p> Signup and view all the answers

A patient with advanced gastric cancer presents with an enlarged liver (hepatomegaly) and palpable lymph nodes in the supraclavicular region. What does this suggest about the progression of the patient's cancer?

<p>The cancer has likely metastasized, indicating a more advanced stage. (B)</p> Signup and view all the answers

A client with gastritis is prescribed sucralfate (Carafate). Which instruction should the nurse include when teaching the client about this medication?

<p>Take the medication one hour before meals. (D)</p> Signup and view all the answers

A patient with a history of chronic kidney disease (CKD) and gastritis requires an antacid. Which antacid would be the MOST appropriate choice?

<p>Aluminum hydroxide (A)</p> Signup and view all the answers

A client is prescribed famotidine for gastritis. What is the MOST important instruction the nurse should provide to the client regarding when to take this medication?

<p>Take it as a single dose at bedtime. (A)</p> Signup and view all the answers

A patient is prescribed omeprazole for treatment of gastritis. The nurse is providing education about this medication. Which statement indicates a correct understanding of how to take this medication?

<p>&quot;I need to take this medication 30 minutes before I eat.&quot; (D)</p> Signup and view all the answers

What is the MOST significant reason for administering antacids two hours after meals and at bedtime?

<p>To coincide with the period of highest hydrogen ion load in the stomach. (B)</p> Signup and view all the answers

A patient who is prescribed bismuth subsalicylate for gastritis asks the nurse if it is okay to take aspirin for a headache. What is the nurse's BEST response?

<p>&quot;No, aspirin should be avoided while taking bismuth subsalicylate because it can lead to an overdose of salicylic acid.&quot; (D)</p> Signup and view all the answers

A nurse is preparing to administer IV pantoprazole to a patient with gastritis. Which of the following actions is MOST important for the nurse to take?

<p>Administer the medication through a dedicated IV line using a pump and filter. (D)</p> Signup and view all the answers

A patient with gastritis is prescribed lansoprazole. The nurse knows to provide which instruction regarding when to administer this medication?

<p>30 minutes before the main meals of the day (C)</p> Signup and view all the answers

A nurse is caring for a client receiving esomeprazole. Which assessment is MOST important for the nurse to perform related to the administration of this medication?

<p>Assess for hepatic impairment. (D)</p> Signup and view all the answers

A patient with gastritis is prescribed magnesium hydroxide with aluminum hydroxide. What focused assessment should the nurse prioritize before starting this medication?

<p>History of chronic kidney disease or heart failure (A)</p> Signup and view all the answers

Flashcards

CBC for Gastritis

Complete blood count; assesses for anemia, indicated by hemoglobin levels (less than 12 in females, less than 14 in males).

Gastritis Treatment Focus

Primarily focuses on treating the underlying cause and managing the symptoms.

H2-Receptor Antagonists

Decrease gastric acid secretions by blocking histamine receptors in parietal cells.

Famotidine Timing

Administer as a single dose at bedtime to suppress nocturnal acid production.

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Mucosal Barrier Fortifiers

Protect the stomach mucosa from damage.

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Sucralfate Timing

Administer one hour before meals or two hours after, and at bedtime, as food interferes with adherence to mucosa.

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Antacids

Increase the pH of gastric contents by deactivating pepsin.

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Antacid Drug Interactions

Taking other medications 1-2 hours apart from antacids because antacids interfere with absorption.

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Proton Pump Inhibitors (PPIs)

Suppress gastric acid secretion by inhibiting the H+/K+-ATPase enzyme system.

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PPI Timing

Administer 30 minutes before the main meals of the day because the proton pump is activated by the presence of food.

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Metronidazole for H. pylori

An antibiotic used to treat H. pylori infections; take with food to minimize nausea.

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Clarithromycin and Renal Impairment

An antibiotic for H. pylori; use carefully in patients with kidney problems and monitor their BUN levels.

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Amoxicillin Administration

An antibiotic used for treating H. pylori infections; should be taken with or immediately after food.

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Misoprostol Contraindications

Avoid in pregnant women; can trigger abortion, premature birth, or birth defects; this drug protects the stomach mucosa.

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Gastric Cancer

Begins in the stomach's glands; often found late due to lack of early symptoms; linked to age and H. pylori.

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Gastric Cancer: Lymph Node Involvement

Advanced gastric cancer may cause enlarged lymph nodes, specifically in the supraclavicular chain or at the umbilicus.

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Gastric Cancer: Hepatomegaly

Advanced gastric cancer can cause liver enlargement.

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Gastric Cancer Diagnosis: EGD with Biopsy

An upper endoscopy with biopsy is a key diagnostic procedure for gastric cancer.

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Gastric Cancer: CEA Significance

An elevated CEA level can indicate the presence of colorectal cancer, useful but not definitive as other conditions can elevate it too.

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Gastric Cancer: Early Symptoms

Early symptoms of gastric cancer are often vague and may include indigestion or abdominal discomfort.

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Study Notes

  • The note cover a range of gastrointestinal (GI) and colorectal conditions and procedures to address them

Current Health Assessment:

  • Includes questions of last bowel movement (and whether normal), current changes (color, consistency, frequency), and last menstrual period (for 10-65 year olds).

Patient History:

  • Includes surgical history and skin changes (itching, color, bruising, tendency to bleed)

Nutrition History Assessment:

  • Inquires about normal eating habits, stopped foods (due to stomach issues), cultural preferences (spicy foods, fasting), and lactose intolerance.
  • Notes any health problems that affect nutrition which could lead to decreased appetite, changes/loss of taste, or anorexia.
  • Checks for difficulty swallowing or pain with swallowing/chewing.
  • Considers dentition (condition as well as ill fitted dentures) and unintentional weight loss or gain.
  • Includes use of a large amount of caffeine/ETOH, smoking.
  • Assesses access to a balanced diet (consider income limitations), which includes no assess to fresh fruits and vegetables (food desert)
  • Checks for use of OTC medications and herbal remedies for abdominal issues

Family History:

  • Assess for any Colon cancer history (especially within first degree relatives)

Physical Assessment:

  • Requires that the bladder is emptied
  • Patient should be lying flat with the arms relaxed at the sides and knees slightly flexed.
  • Inspect the abdomen for movement, color, symmetry, and distention.
  • Auscultate to check for high-pitched sounds (q 5-15 seconds), decreased/absent sounds (listen for full 5 minutes), bruits (whooshing sound), and borborygmi (loud, high-pitched gurgling).
  • Percuss to determine the size of solid organs.
  • Palpate to detect masses/fluid/air and tympanic/dull sounds and tenderness or masses.

Labs:

  • A complete blood count (CBC): checks for anemia and infection.
  • Blood tests for decreased calcium, potassium, and sodium.
  • Liver function tests: aspartate aminotransferase (AST) and alanine aminotransferase (ALT).
  • Amylase and lipase: for acute pancreatitis (elevated within 24 hours and can last up to 5 days).
  • Ammonia levels: especially in alcoholics, pancreatitis, and cholecystitis patients.
  • Cancer antigen 19-9 (CA 19-9)/carcinoembryonic antigen (CEA): oncofetal antigen test for cancer therapies/recurrency.
  • Blood test for levels of: bilirubin and coagulation studies (PT).
  • Stool tests: fecal occult blood test (FOBT), ova and parasites, fecal fats (for malabsorption), and Clostridium difficile.

Diagnostic Assessments:

  • Abdominal ultrasound, X-ray, Magnetic Resonance Imaging (MRI), and Computed Tomography (CT).
  • Abdominal CT: Assess allergies to shellfish/iodine. Hold metformin (diabetics) 24 hours before and 48 hours after (can cause contrast-induced renal failure).
  • Endoscopies: small bowel endoscopy, esophagogastroduodenoscopy (EGD), endoscopic retrograde cholangiopancreatography (ERCP), virtual colonoscopy (CT colonography), and a colonoscopy (age 45 or older; every 10 years).
  • Bowel prep (liquid/pill form; enema), hold anticoagulants/aspirin 5 days prior, drink electrolyte replacements (clear liquid diet), and no red, orange, or purple dye. Biopsy may cause a small amount of blood, report larger amounts due to risk of perforation and no fluids until flatus occurs after surgery
  • Sigmoidoscopy performed every five years in patients 45 years and older.
  • Liver-Spleen Scan uses of a radioactive chemical through IV and requires checking pregnant/breastfeeding status. Use careful hand hygiene because residual chemical will be excreted.

Effects of Aging on the GI Tract:

  • Atrophy of gastric mucosa: risk for decreased food breakdown, decreased protein/vitamin B12/iron absorption, and increased bacterial growth. Interventions: dietary changes, easier-to-digest foods, supplemental vitamins/minerals (calcium, zinc, iron, vitamin B12).
  • Decreased peristalsis: can cause decreased sensation on urge to defecate, constipation, and fecal impaction. Interventions: dietary changes, laxatives, and scheduled bowel routine.
  • Calcification of pancreatic vessels: can cause distention/dilation of pancreatic duct, inability to absorb fat solute vitamins (A, E, D, K), inability to digest and store fat, fatty stools, and decreased lipase levels. Interventions: pancreatic enzymes, vitamin supplements.
  • Decreased number/size of hepatic cells: can cause decreased ability to metabolize drugs, leading to toxicity. Adjust medication dose.
  • Decreased aerobic/anaerobic flora: impacts disease response, obesity, and inflammatory disease. Interventions include prebiotics and probiotics.
  • Function of the stomach includes digestion and as an endocrine organ and reservoir.

Gastritis:

  • Inflammation/breakdown of gastric mucosa, it is not typically treated in hospital unless there is GI bleed or fluid/electrolyte imbalance.
  • Acute gastritis has a sudden onset with a short duration due to exposure of gastric mucosa to a local irritant (H. pylori, contaminated food/water), changes to the stomach/duodenum, NSAID use, ETOH, caffeine, steroids, smoking, stress, reflux of bile salts, contaminated foods/water. Check if they have traveled anywhere.
  • Diagnosis is confirmed viewing irritation with a colonoscopy.
  • Recognizing this condition includes rapid onset of epigastric pain (increased/decreased with eating), hiccupping (several hours/days), N/V, anorexia, intolerance of spicy/fatty foods, cramping, dyspepsia, and hematemesis/melena.
  • The gastric mucosa during acute conditions can resolve on its own within a few days of onset.
  • Chronic gastritis is often related to autoimmune disorder with persistent inflammation deep into the mucosa, and inflammation is more widespread. The gastric walls thin and atrophy.
  • Causes include: pernicious anemia, H. pylori, age (declining stomach lining), and GERD.
  • Visual appearance on colonoscopy will show very deep erosions coving almost the entire gastric mucosa.
  • Recognizing this condition includes nausea/vomiting, epigastric discomfort after eating, and abdominal pain (deep, persistent, and widespread).
  • Diagnosis of gastritis includes EGD with biopsy (gold standard). NPO 6-8 hours prior; outpatient basis but need driver due to IV sedation; sore throat can occur (lidocaine spray can be given); and monitor for manifestations of perforation (chest/abdominal pain, fever, nausea, vomiting, abdominal distention).
  • Blood samples check for elevated levels IgG/IgM (anti-H pylori antibodies produced by immune system in response to H. pylori infection) and CBC to check for anemia (less than 12 in females and less than 14 in males).
  • Treatment includes treating the cause and limit foods that cause irritation (spicy, alcohol, caffeine).
  • Surgical interventions are rare.

Medications for the Treatment of Gastritis:

  • H2-receptor antagonist decreases gastric secreations, blocking histamine receptors in peridontal cells.
  • Mucosal barrier fortifiers protect stomach mucosa: sucralfate (Carafate) give one hour before or two hours after meals, at bedtime (food interferes with drug adhering to mucosa.)
  • Antacids increase the pH. Magnesium Hydroxide with aluminum hydroxide (give 2 hrs after meals and at bedtime for higher hydrogen ion load and use liquid rather than tablets.
  • Proton pump inhibitors (PPIs) suppress HK-ATPase enzyme system of gastric acid secretion to suppress acid: Omeprazole, Lansoprazole, Rabeprazole, Pantoprazole, Esomeprazole.
  • Antimicrobials treat H. pylori infection: Metronidazole, Clarithromycin, Amoxicillin, and Tetracycline.
  • Prostaglandin analogs stimulate mucosal and decreases gastric secretions: Misoprostol

Gastric Cancer:

  • Adenocarcinoma that begins in the glands and cells of the stomach mucosa is curable if caught early.
  • The 5-year survival rate of adults with stomach cancer in US is poor due to lack of symptoms until disease advances thus there are high chane of metastasis. Increase in those older then 50.
  • Causes include H. pylori infection, HPV, Streptococcus Bovis, chronic gastritis, gastric pollyps, gastric surgery, smoking, heavy alcohol use, diet (pickled foods, low intake of fruits and vegetables
  • Early recognizing cues include diet changes, most often ignore or tumor grows. advanced includes weight and fatigue due to lack of nutrition
  • Diagnostic includes EDG with biopsey and endoscopic ultrasound

Gastric Cancer Treatment:

  • Involves chemotherapy to prolong survival, and radiation for palliative care.
  • Surgery: resection is preferred, plus insertion to remove secretions.
  • Post-op: monitor chest and abdominal pain, CT and MRI scans, elevated CEA in people with CRC.

Colostomys:

  • Total gastrectomy entire stomach removed and small intestine connected to oesophagus which requires Pre-op care.
  • Ascending colostomy and descending colostomy are to prevent tumor growth
  • Aftercare: Perineal wound care, prevent compliations, and pain releif
  • Treatment for UC and Crohn's Disease to decrease diarhea using non surgical and surgical inventions. Provide skin protect and Nutrition for the patient. Total Colectomy to remove colon if other treatments wont work

Intestinal and Rectal Disorders:

  • Irritable bowel syndrome includes abnominal swelling causing pain due to bowl issues. Which can cause stress or anxiety and make the patient smoke more.
  • Hydrogen breath test, small frequent meals and pain medication can treat bowel bacterial
  • Diverticula: hypertrophy and thickening of colon and infection in those area. Needs high fiber high fluid or may cause a bleed

Chron's Disease:

  • Is a chronic disorder with symptoms like Diarrhea and fatigue. Its test and lab are decrease album and folic acis levels with elevated
  • Treat with medications that are Non Surgical
  • Ulcerarive Coltis is similar but requires more surgical and drug therapy.

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