10 Questions
function of plasma protein
Contribute to the viscocity of the plasma 2.Responsible for osmotic return of filtered fluid from interstitial fluid compartment 3.Create suspension stability in blood aiding maintainance of dispersion of materials 4.Reserve of amino acid for the body 5.Blood buffers (15% of blood buffering capacity) 6.Transport of CO2 in blood 7.Transport of Hormones , urea, lipids, glucose
examples of plasma protein
albumin, globulin and fibrinogen
albumin
From d liver ●Most abundant (55-64%) ●4-5g/100mls of blood (3.5-5g/dl) ●D smallest size wit molecular weight of 69000- 70000 ●Total exchangeable albumin pool=4-5g/kg bodyweight ●38-45% intravascular ●10% of exchangeable pool degraded daily ●Replacement comes from hepatic cells producing 200 to 400mg/kg/day ●Synthesis decreases in fasting and increase in nephrosis because of loss in urine
globulin
From d liver ●Most abundant (55-64%) ●4-5g/100mls of blood (3.5-5g/dl) ●D smallest size wit molecular weight of 69000- 70000 ●Total exchangeable albumin pool=4-5g/kg bodyweight ●38-45% intravascular ●10% of exchangeable pool degraded daily ●Replacement comes from hepatic cells producing 200 to 400mg/kg/day ●Synthesis decreases in fasting and increase in nephrosis because of loss in urine
fibrinogen
From liver ●Only soluble plasma protein ●Molecular weight = 350,000 ● Amount in circulation = 0.15- 0.3g/100ml ●Converted to fibrin as blood coagulates
total cholesterol is the sum of what
hdl + ldl + 20% triglyceride value
high ldl values are bad
True
high hdl values are good
True
cardiac risk ratio
total cholestrol divided by hdl cholesterol
when is a cardiac risk ratio considered a warning
greater than 7
serum lipids
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