Cell injury and death
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Questions and Answers

What increases Bim, Bid, and Bad, Puma, Noxa (BH3 only)?

  • ER stress, DNA damage, lack of growth signals (correct)
  • Lack of BH4 molecules
  • Cytochrome c leaks into the cytosol
  • BH3 molecules

    • What activates the mitochondrial leak channel (Bax/Bak)?

  • BH3 molecules only and lack of BH4 molecules (correct)
  • ER stress, DNA damage, lack of growth signals
  • Cytochrome c leaks into the cytosol
  • Increase in BH4 molecules

    • What happens if you open the mitochondrial leak channel?

  • DNA damage, ER stress, lack of growth signals
  • Cytochrome c leaks into cytosol (correct)
  • Increase in BH4
  • BH3 molecules only are triggered

    • Lack of growth factor triggers apoptosis in which of the following ways:

    <p>triggers apoptosis through intrinsic (mitochondrial) pathways</p> Signup and view all the answers

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