Podcast
Questions and Answers
What is the enzyme responsible for the conversion of tyrosine to noradrenaline?
What is the enzyme responsible for the conversion of tyrosine to noradrenaline?
How is dopamine actively packaged into vesicles?
How is dopamine actively packaged into vesicles?
What is the primary mechanism for the release of noradrenaline?
What is the primary mechanism for the release of noradrenaline?
What is the primary mechanism for the termination of noradrenaline action?
What is the primary mechanism for the termination of noradrenaline action?
Signup and view all the answers
What is the primary enzyme responsible for the degradation of noradrenaline?
What is the primary enzyme responsible for the degradation of noradrenaline?
Signup and view all the answers
Which receptor type functions as inhibitory receptors and autoreceptors reducing noradrenaline release?
Which receptor type functions as inhibitory receptors and autoreceptors reducing noradrenaline release?
Signup and view all the answers
Which physiological response is associated with noradrenaline at the cellular level?
Which physiological response is associated with noradrenaline at the cellular level?
Signup and view all the answers
Which neurotransmitter deficiency is thought to underlie depression?
Which neurotransmitter deficiency is thought to underlie depression?
Signup and view all the answers
What is the most established neurochemical theory underlying depression?
What is the most established neurochemical theory underlying depression?
Signup and view all the answers
Which type of antidepressant drugs prevents the reuptake of serotonin and/or noradrenaline?
Which type of antidepressant drugs prevents the reuptake of serotonin and/or noradrenaline?
Signup and view all the answers
What is the primary mechanism of action of monoamine reuptake inhibitors in the acute phase?
What is the primary mechanism of action of monoamine reuptake inhibitors in the acute phase?
Signup and view all the answers
What adaptive changes in the brain are associated with chronic antidepressant treatment?
What adaptive changes in the brain are associated with chronic antidepressant treatment?
Signup and view all the answers
Which neurotransmitter is thought to underlie depression?
Which neurotransmitter is thought to underlie depression?
Signup and view all the answers
Which enzyme is responsible for the degradation of serotonin?
Which enzyme is responsible for the degradation of serotonin?
Signup and view all the answers
What is the primary site of cells bodies for noradrenaline in the brain?
What is the primary site of cells bodies for noradrenaline in the brain?
Signup and view all the answers
Which receptor type is an inhibitory autoreceptor reducing serotonin release?
Which receptor type is an inhibitory autoreceptor reducing serotonin release?
Signup and view all the answers
What is the primary mechanism for the release of serotonin?
What is the primary mechanism for the release of serotonin?
Signup and view all the answers
Which enzyme is responsible for the conversion of tryptophan to serotonin?
Which enzyme is responsible for the conversion of tryptophan to serotonin?
Signup and view all the answers
Which physiological response is associated with serotonin at the behavioral level?
Which physiological response is associated with serotonin at the behavioral level?
Signup and view all the answers
Which neurotransmitter is associated with cells bodies in the raphe nuclei?
Which neurotransmitter is associated with cells bodies in the raphe nuclei?
Signup and view all the answers
Which of the following SSRIs is also an antagonist at 5-HT2C receptors?
Which of the following SSRIs is also an antagonist at 5-HT2C receptors?
Signup and view all the answers
What is a potential risk of SSRIs for children and adolescents under 18 years?
What is a potential risk of SSRIs for children and adolescents under 18 years?
Signup and view all the answers
What condition can SSRIs also be used to treat besides depression?
What condition can SSRIs also be used to treat besides depression?
Signup and view all the answers
Which side effect is NOT commonly associated with SSRIs?
Which side effect is NOT commonly associated with SSRIs?
Signup and view all the answers
Which of the following is a side effect of tricyclic antidepressants due to H1 block?
Which of the following is a side effect of tricyclic antidepressants due to H1 block?
Signup and view all the answers
What is a serious risk associated with the use of Monoamine Oxidase Inhibitors (MAOIs) and certain foods?
What is a serious risk associated with the use of Monoamine Oxidase Inhibitors (MAOIs) and certain foods?
Signup and view all the answers
What type of antidepressant is Mirtazapine classified as?
What type of antidepressant is Mirtazapine classified as?
Signup and view all the answers
Which of the following is NOT a main selective serotonin reuptake inhibitor (SSRI)?
Which of the following is NOT a main selective serotonin reuptake inhibitor (SSRI)?
Signup and view all the answers
Which of the following is a potential side effect of SSRIs when combined with MAO inhibitors?
Which of the following is a potential side effect of SSRIs when combined with MAO inhibitors?
Signup and view all the answers
What is a common use for SNRIs besides treating depression?
What is a common use for SNRIs besides treating depression?
Signup and view all the answers
Which of the following is NOT a tricyclic antidepressant (TCA)?
Which of the following is NOT a tricyclic antidepressant (TCA)?
Signup and view all the answers
Which of the following antidepressants is known to interact with CypP450 enzymes, posing a serious risk of drug-drug interactions?
Which of the following antidepressants is known to interact with CypP450 enzymes, posing a serious risk of drug-drug interactions?
Signup and view all the answers
