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Questions and Answers
What is the enzyme responsible for the conversion of tyrosine to noradrenaline?
What is the enzyme responsible for the conversion of tyrosine to noradrenaline?
- Tyrosine decarboxylase
- Tyrosine hydroxylase
- DOPA decarboxylase (correct)
- Tyrosine oxidase
How is dopamine actively packaged into vesicles?
How is dopamine actively packaged into vesicles?
- By an amine transporter (correct)
- By a noradrenaline transporter
- By a serotonin transporter
- By a dopamine transporter
What is the primary mechanism for the release of noradrenaline?
What is the primary mechanism for the release of noradrenaline?
- Facilitated diffusion
- Passive diffusion
- Active transport
- Classical Ca2+-mediated exocytosis (correct)
What is the primary mechanism for the termination of noradrenaline action?
What is the primary mechanism for the termination of noradrenaline action?
What is the primary enzyme responsible for the degradation of noradrenaline?
What is the primary enzyme responsible for the degradation of noradrenaline?
Which receptor type functions as inhibitory receptors and autoreceptors reducing noradrenaline release?
Which receptor type functions as inhibitory receptors and autoreceptors reducing noradrenaline release?
Which physiological response is associated with noradrenaline at the cellular level?
Which physiological response is associated with noradrenaline at the cellular level?
Which neurotransmitter deficiency is thought to underlie depression?
Which neurotransmitter deficiency is thought to underlie depression?
What is the most established neurochemical theory underlying depression?
What is the most established neurochemical theory underlying depression?
Which type of antidepressant drugs prevents the reuptake of serotonin and/or noradrenaline?
Which type of antidepressant drugs prevents the reuptake of serotonin and/or noradrenaline?
What is the primary mechanism of action of monoamine reuptake inhibitors in the acute phase?
What is the primary mechanism of action of monoamine reuptake inhibitors in the acute phase?
What adaptive changes in the brain are associated with chronic antidepressant treatment?
What adaptive changes in the brain are associated with chronic antidepressant treatment?
Which neurotransmitter is thought to underlie depression?
Which neurotransmitter is thought to underlie depression?
Which enzyme is responsible for the degradation of serotonin?
Which enzyme is responsible for the degradation of serotonin?
What is the primary site of cells bodies for noradrenaline in the brain?
What is the primary site of cells bodies for noradrenaline in the brain?
Which receptor type is an inhibitory autoreceptor reducing serotonin release?
Which receptor type is an inhibitory autoreceptor reducing serotonin release?
What is the primary mechanism for the release of serotonin?
What is the primary mechanism for the release of serotonin?
Which enzyme is responsible for the conversion of tryptophan to serotonin?
Which enzyme is responsible for the conversion of tryptophan to serotonin?
Which physiological response is associated with serotonin at the behavioral level?
Which physiological response is associated with serotonin at the behavioral level?
Which neurotransmitter is associated with cells bodies in the raphe nuclei?
Which neurotransmitter is associated with cells bodies in the raphe nuclei?
Which of the following SSRIs is also an antagonist at 5-HT2C receptors?
Which of the following SSRIs is also an antagonist at 5-HT2C receptors?
What is a potential risk of SSRIs for children and adolescents under 18 years?
What is a potential risk of SSRIs for children and adolescents under 18 years?
What condition can SSRIs also be used to treat besides depression?
What condition can SSRIs also be used to treat besides depression?
Which side effect is NOT commonly associated with SSRIs?
Which side effect is NOT commonly associated with SSRIs?
Which of the following is a side effect of tricyclic antidepressants due to H1 block?
Which of the following is a side effect of tricyclic antidepressants due to H1 block?
What is a serious risk associated with the use of Monoamine Oxidase Inhibitors (MAOIs) and certain foods?
What is a serious risk associated with the use of Monoamine Oxidase Inhibitors (MAOIs) and certain foods?
What type of antidepressant is Mirtazapine classified as?
What type of antidepressant is Mirtazapine classified as?
Which of the following is NOT a main selective serotonin reuptake inhibitor (SSRI)?
Which of the following is NOT a main selective serotonin reuptake inhibitor (SSRI)?
Which of the following is a potential side effect of SSRIs when combined with MAO inhibitors?
Which of the following is a potential side effect of SSRIs when combined with MAO inhibitors?
What is a common use for SNRIs besides treating depression?
What is a common use for SNRIs besides treating depression?
Which of the following is NOT a tricyclic antidepressant (TCA)?
Which of the following is NOT a tricyclic antidepressant (TCA)?
Which of the following antidepressants is known to interact with CypP450 enzymes, posing a serious risk of drug-drug interactions?
Which of the following antidepressants is known to interact with CypP450 enzymes, posing a serious risk of drug-drug interactions?
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