Wound Infection: Sources and Contributing Factors

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Questions and Answers

Which of the following scenarios poses the HIGHEST risk of wound infection due to the nature of the wound itself?

  • A clean surgical incision made under sterile conditions.
  • A deep puncture wound contaminated with soil. (correct)
  • A superficial paper cut on a healthy individual.
  • A well-managed thermal burn with minimal tissue damage.

A patient undergoing elective knee replacement surgery is assessed to determine the need for prophylactic antibiotics. Which factor would MOST strongly suggest the necessity for antibiotic prophylaxis?

  • The patient is generally healthy with no existing infections.
  • The patient has a known history of MRSA colonization. (correct)
  • The patient has a history of seasonal allergies.
  • The patient has a slightly elevated white blood cell count.

During a surgical procedure, a circulating nurse observes a breach in sterile technique that leads to potential contamination of the surgical site. According to the information provided, what is the MOST critical timeframe for intervention to minimize the risk of subsequent wound infection?

  • Within 24 hours after contamination.
  • After visible signs of infection appear.
  • Within the first 3 hours after contamination. (correct)
  • Immediately before wound closure.

A patient with diabetes develops a foot ulcer with significant necrotic tissue. Which of the following factors associated with the wound environment is MOST likely to impair the body's ability to combat infection?

<p>Presence of edema. (C)</p> Signup and view all the answers

A surgeon is closing a surgical wound and applies sutures. Which of the following suture techniques would MOST likely increase the risk of wound infection?

<p>Using excessively tight sutures that cause vascular strangulation. (C)</p> Signup and view all the answers

Which of the following patient conditions would MOST significantly increase the susceptibility to wound infections?

<p>Compromised immune system due to chemotherapy. (C)</p> Signup and view all the answers

A patient presents with a traumatic wound acquired while gardening. What type of environmental pathogen should be of PRIMARY concern in this case?

<p><em>Clostridium tetani</em>. (D)</p> Signup and view all the answers

An abdominal stab wound contaminated by colonic bacteria increases the risk of infection. What is this an example of?

<p>Patient's normal flora. (D)</p> Signup and view all the answers

What is NOT a factor contributing to wound infections?

<p>Good oxygenation. (C)</p> Signup and view all the answers

A patient has undergone a splenectomy and is now at higher risk of infection. What is the BEST plan?

<p>Administer prophylactic antibiotic prior to surgery. (B)</p> Signup and view all the answers

Flashcards

Wounds Prone to Infection

Surgical wounds, traumatic wounds, deep cuts, thermal burns, compound fractures and Physiological wounds such as Endometrial surface post-placenta separation and Umbilical stump are prone to infections.

Sources of Wound Infections

Patient's normal flora, exogenous contamination (e.g., from staff), and environmental pathogens (e.g., soil bacteria) are sources of wound infection

Factors: Wound Infections

Microbial dose and virulence, wound condition (necrosis, edema, poor oxygenation/blood supply), and patient health/immune response influence wound infections.

Wound Conditions & Infection

Necrosis, edema, poor oxygenation, and poor blood supply in the wound bed increase risk of wound infection.

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Preventing Wound Infections

Administer prophylactic antibiotics before high-risk surgery and within the first 3 hours after an injury.

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Prophylactic Antibiotics

Administer antibiotics preemptively to prevent infections in high-risk surgeries.

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Critical Timeframe

The initial 3 hours after wound contamination is critical for preventing infection

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Study Notes

  • Wounds susceptible to infection include surgical wounds, traumatic wounds, deep cuts, thermal burns, compound fractures, frostbite necrosis, and physiological wounds like the endometrial surface post-placenta separation and umbilical stumps.

Sources of Wound Infection

  • Patient's normal flora can cause wound infections. An example includes an abdominal stab wound being contaminated by colonic bacteria.
  • Exogenous contamination results in wound infections. An example includes a clean surgical wound in the OR being contaminated with S. aureus from hospital staff or fomites.
  • Environmental pathogens can lead to wound infections. An example includes a Clostridium tetani spores from the soil entering a splinter.

Factors That Contribute to Wound Infections

  • Microbial contamination dose
  • Microbial virulence
  • Wound condition
  • Necrosis
  • Edema
  • Poor oxygenation
  • Poor blood supply
  • Vascular strangulation due to excessively tight sutures
  • Patient’s health status and immune response

Prevention of Wound Infections

  • The first 3 hours after contamination is critical.
  • Prophylactic antibiotics should be given before surgery.
  • Antibiotics are only given for high-risk surgeries.

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