33 Wound Healing Stages

During the acute inflammatory phase of wound healing, which event contributes most significantly to the development of wound edema?

A surgeon is concerned about the potential for dehiscence in a ventral midline incision on a horse. Which of Halstead's principles, if meticulously followed, would have the MOST significant impact on minimizing this risk?

In the context of wound healing, what is the MOST critical role of macrophages during the destructive phase?

A horse sustained a deep laceration on its lower limb. The wound is heavily contaminated and shows signs of infection. During the destructive phase of wound healing, which enzymatic activity would be MOST detrimental if left unchecked?

Why is elevation of a limb recommended to minimize edema?

Would a tourniquet be a good idea to minimize edema?

What is the most important result of fibrin exudation during the inflammatory phase?

What is the best description of the initial wound strength?

What can result in a wound with no seal?

How long does it take for properly aligned closures to result in an epithelial seal?

During an enterotomy closure, when is the closure most likely to dehisce?

What is the goal of gentle tissue handling?

Why is it important to have accurate hemostasis?

Why is important to have preservation of blood supply?

What is the first stage of healing of surgical wounds?

During the acute inflammatory phase, what occurs to the capillaries?

Which of the following is not a principle of Halsteads principles?

If a patient's wound has a poor seal, this indicates:

When the cellular events are dominated by the leukocytic response, what phase of the healing process is occuring?

When does rapid fibroplasia occur?

During the maturation phase, what occurs to the tensile strength of the wound?

What is the phase that is identified by the predominant cellular events?

What occurs immediately during the hemostasis phase?

Which of the following is not part of the hemostasis phase?

What is the role of collagenase during the destructive phase?

During the maturation phase, what occurs to the vasculature?

What day do fibroblasts appear during the proliferative phase?

When do synthesis and lysis come into balance?

The duration of the inflammatory response:

When an umbilical herniorrhaphy is perfromed, when should the edges be "freshened"?

When would be the best time to administer phenylbutazone to a surgical patient?

Where is phagocytosed material taken up?

When using sharp scalpel excision during debridement, what should one ensure?

How long do you leave skin sutures in for an excision of a 5 cm wound on the side of the carpus?

You suture a flexor tendon laceration. How long does the repair require support?

Based on the Starling equation, which change would MOST directly reduce edema formation in a wound?

Why should soaps or detergents not be used in wounds?

In a surgical wound undergoing second intention healing, which cellular process is MOST directly responsible for wound contraction?

Following the principles of strict asepsis, when is the MOST appropriate time to administer prophylactic antibiotics in a surgical procedure to minimize the risk of surgical site infection?

How does tissue tension primarily impede wound healing at the cellular level?

In a deep, contaminated wound, what is the MOST significant rationale for using sharp scalpel excision during debridement rather than other methods?

In the context of the Starling equation, which physiological change would MOST likely lead to a DECREASE in edema formation in the wound?

In a surgical scenario, which factor has the HIGHEST potential to disrupt the transition from the inflammatory phase to the proliferative phase of wound healing?

Following a surgical procedure, administration of phenylbutazone can impact wound healing. What is the MOST concerning effect on wound healing?

During the maturation phase of wound healing, what represents the MOST critical event that determines the long-term tensile strength of the scar tissue?

What is the MOST concerning reason why soaps or detergents should not be used directly in open wounds?

You suture a flexor tendon laceration on a horse. What is the MOST important consideration when determining the duration of external support required postoperatively?