Wound Healing: Granulation Tissue
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Questions and Answers

What are the two primary components of granulation tissue?

  • Proliferation of new small blood vessels and proliferation of fibroblasts (correct)
  • Deposition of extracellular matrix and wound contraction
  • Proliferation of new small blood vessels and migration of fibroblasts
  • Migration and proliferation of fibroblasts and wound contraction

What is the primary function of myofibroblasts in wound healing?

  • Proliferation of new small blood vessels
  • Deposition of extracellular matrix
  • Wound contraction (correct)
  • Migration of fibroblasts into the site of injury

What is the primary component of extracellular matrix deposited during granulation tissue formation?

  • Elastin
  • Collagen type I
  • Collagen (correct)
  • Collagen type II

When does the formation of myofibroblasts begin during wound healing?

<p>At day 6 (D)</p> Signup and view all the answers

What is the term for the process of transformation of fibroblasts to muscle-like fibers during wound healing?

<p>Myofibroblast transformation (C)</p> Signup and view all the answers

What is the characteristic of healing by primary intention?

<p>Minimum amount of time with minimal scar formation (B)</p> Signup and view all the answers

What is the primary outcome of repair by scar formation?

<p>Replacement by connective tissue (B)</p> Signup and view all the answers

What occurs as early as 24 hours after injury in granulation tissue formation?

<p>Fibroblasts and vascular endothelial cells begin proliferating (A)</p> Signup and view all the answers

What is the characteristic appearance of young granulation tissue on the surface of the wound?

<p>Pink, soft, and granular (B)</p> Signup and view all the answers

What is the result of the remodeling phase of wound healing?

<p>Maturation of collagen (B)</p> Signup and view all the answers

What type of cells are most likely to undergo regeneration in tissue repair?

<p>Labile cells (A)</p> Signup and view all the answers

What is the term for the replacement of injured tissue with connective tissue in tissue repair?

<p>Scar formation (C)</p> Signup and view all the answers

What is a characteristic of secondary union healing?

<p>Intense inflammatory reaction (C)</p> Signup and view all the answers

What is a factor that can affect collagen synthesis and wound healing?

<p>Protein deficiency (B)</p> Signup and view all the answers

What is formed during the granulation tissue phase of wound healing?

<p>Macrophages (C)</p> Signup and view all the answers

What is a result of wound contraction during secondary union healing?

<p>5 to 10% reduction in wound size (A)</p> Signup and view all the answers

What is deposited during the ECM deposition phase of wound healing?

<p>Collagen (A)</p> Signup and view all the answers

What is the final outcome of the wound healing process?

<p>Scar tissue (C)</p> Signup and view all the answers

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