What is DNA?
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Which of the following best describes the contribution of Rosalind Franklin to the discovery of DNA's structure?

  • She identified DNA as the transformative factor responsible for passing on genetic information.
  • Her work provided crucial data that Watson and Crick used to develop their double helix model, though she did not receive a Nobel Prize for it. (correct)
  • She discovered the base pairing rules, noting that adenine always binds with thymine and guanine with cytosine.
  • She isolated DNA for the first time and recognized it as a unique molecule.

If a strand of DNA has the sequence 5'-G-C-T-A-T-G-C-3', what would be the sequence of its complementary strand?

  • 3'-G-C-T-A-T-G-C-5'
  • 5'-G-C-T-A-T-G-C-3'
  • 3'-C-G-A-T-A-C-G-5' (correct)
  • 5'-C-G-A-T-A-C-G-3'

During DNA replication, which enzyme is responsible for separating the double helix structure of DNA?

  • Polymerase
  • Ligase
  • Helicase (correct)
  • Primase

Which statement accurately describes Chargaff's rule and its significance to DNA structure?

<p>Chargaff's rule states that the amount of adenine is always equal to the amount of thymine, and the amount of guanine is always equal to the amount of cytosine, which provided key evidence for base pairing in the double helix. (A)</p> Signup and view all the answers

A mutation occurs where a single nucleotide base is changed in a DNA sequence. Which component of the nucleotide is directly affected by this mutation?

<p>The nitrogenous base (C)</p> Signup and view all the answers

Why is DNA replication essential before cell division?

<p>To ensure each daughter cell receives a complete and identical copy of the genetic material. (C)</p> Signup and view all the answers

Which of the following correctly pairs a nitrogenous base with its classification as either a purine or a pyrimidine?

<p>Thymine - Pyrimidine (A)</p> Signup and view all the answers

Given that DNA contains the blueprint for an organism's traits, in what way does the sequence of bases directly influence these traits?

<p>The specific order of bases codes for genes, which determine the traits or characteristics in living things. (C)</p> Signup and view all the answers

What is the role of hydrogen bonds in the structure of DNA?

<p>To connect complementary nitrogenous bases, stabilizing the double helix structure. (B)</p> Signup and view all the answers

How did the work of Friedrich Miescher contribute to our current understanding of DNA?

<p>Miescher discovered the existence of DNA. (C)</p> Signup and view all the answers

Which of the following best describes how Watson and Crick determined the structure of DNA?

<p>They compiled existing research, most notably that of Rosalind Franklin, to deduce DNA's double helix structure. (A)</p> Signup and view all the answers

Why is the process of DNA replication described as 'unzipping' in its initial phase?

<p>Because the two DNA strands are separated by breaking the hydrogen bonds between base pairs. (C)</p> Signup and view all the answers

How did Erwin Chargaff's work contribute to the understanding of DNA structure?

<p>He established the base pairing rules, showing that adenine pairs with thymine and guanine pairs with cytosine. (A)</p> Signup and view all the answers

If a DNA molecule is found to have 22% of its bases as guanine, what percentage of its bases are adenine?

<p>28% (A)</p> Signup and view all the answers

What is the role of the enzyme helicase during DNA replication?

<p>To unwind the DNA double helix by breaking hydrogen bonds. (A)</p> Signup and view all the answers

During which phase of the cell cycle does DNA replication primarily occur, ensuring each daughter cell receives a complete set of genetic information?

<p>The S phase (Synthesis) (B)</p> Signup and view all the answers

Which component of a nucleotide is directly responsible for the diversity of genetic information in DNA?

<p>The nitrogenous base (A)</p> Signup and view all the answers

Why are hydrogen bonds, rather than covalent bonds, used to link complementary base pairs in DNA?

<p>Hydrogen bonds allow for easy separation of DNA strands during replication and transcription. (A)</p> Signup and view all the answers

Which of the following distinguishes a purine from a pyrimidine?

<p>A purine has a double-ring structure, while a pyrimidine has a single-ring structure. (C)</p> Signup and view all the answers

DNA is considered the 'blueprint' for an organism. What aspect of DNA is most directly responsible for determining an organism's traits?

<p>The sequence of nitrogenous bases (C)</p> Signup and view all the answers

Flashcards

What does DNA stand for?

Deoxyribonucleic Acid, the molecule containing the genetic instructions for all known living organisms.

Who is Friedrich Miescher?

He discovered the existence of DNA in 1869.

Who is Oswald Avery?

He discovered DNA as the “transformative factor” responsible for passing on information in 1944.

Who are James Watson and Francis Crick?

They discovered the structure of DNA in 1953.

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What is the structure of DNA?

DNA's structure is a double helix (twisted staircase).

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What is DNA?

A large molecule (polymer) that falls under the category of nucleic acid.

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What are nucleotides?

The monomers that make up nucleic acids (like DNA).

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What are the nitrogenous bases in DNA?

Adenine (A), Guanine (G), Cytosine (C), and Thymine (T).

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What is Chargaff’s Rule?

Adenine always binds with Thymine, and Guanine always binds with Cytosine.

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What is Helicase?

The enzyme that separates the hydrogen bonds between base pairs during DNA replication.

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What is a chromosome?

Tightly wound chromatin forming a visible structure.

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What is DNA's function?

The blueprint for designing an organism, unique to each individual (except identical twins).

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What is a polymer?

A large molecule made up of monomers.

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What is nucleic acid?

A category of large molecules, DNA falls under this category.

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What are purines?

Adenine (A) and Guanine (G).

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What are pyrimidines?

Cytosine (C) and Thymine (T).

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Who is Erwin Chargaff?

He discovered that Adenine always binds with Thymine and Guanine always binds with Cytosine.

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What are hydrogen bonds?

The type of bond between nitrogenous bases in DNA.

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What are bases?

The sequence of these determine traits in living things.

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What is interphase?

DNA replication happens during this phase.

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Study Notes

  • Chromatin is genetic material composing DNA, RNA, and proteins, forming chromosomes in eukaryotic organism nuclei.

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Related Documents

DNA Notes PDF

Description

DNA encodes an organism's genetic blueprint and is unique to each individual. It is a large polymer categorized as a nucleic acid, which consists of linked nucleotides. A nucleotide comprises phosphate, deoxyribose, and a nitrogenous base.

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