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Questions and Answers
What does the Therapeutic Index (TI) measure?
What does the Therapeutic Index (TI) measure?
- The maximum effect obtainable by a drug
- The absorption rate of a drug in the body
- The range of blood concentrations of a medicine
- The difference between the desired effect and the undesired effect of a drug (correct)
How is the Therapeutic Window defined?
How is the Therapeutic Window defined?
- A range of blood concentrations above the toxic level of a medicine
- A range of blood concentrations between therapeutic and toxic levels of a medicine (correct)
- The maximum effect obtainable by a drug
- The minimum effective dose of a drug
What would a low Therapeutic Index suggest about a drug?
What would a low Therapeutic Index suggest about a drug?
- It is highly effective
- It has low safety margin (correct)
- It is not potent
- It is safe
How do potency and effectiveness differ?
How do potency and effectiveness differ?
What is the primary difference between potency and effectiveness?
What is the primary difference between potency and effectiveness?
Which drug has the highest Therapeutic Index based on the provided information?
Which drug has the highest Therapeutic Index based on the provided information?
True or False: The greater the Therapeutic Index (TI), the less safe the drug.
True or False: The greater the Therapeutic Index (TI), the less safe the drug.
What defines a drug according to the text?
What defines a drug according to the text?
True or False: A low Therapeutic Index suggests that a drug has high safety.
True or False: A low Therapeutic Index suggests that a drug has high safety.
What characterizes psychoactive drugs according to the text?
What characterizes psychoactive drugs according to the text?
What is the purpose of drug names according to the text?
What is the purpose of drug names according to the text?
What is the importance of generic drugs as mentioned in the text?
What is the importance of generic drugs as mentioned in the text?
What are excipients in drug names as explained in the text?
What are excipients in drug names as explained in the text?
Why do policymakers suggest different sentences based on LSD presentation according to the text?
Why do policymakers suggest different sentences based on LSD presentation according to the text?
Who criticized policymakers for their ignorance about drugs according to the text?
Who criticized policymakers for their ignorance about drugs according to the text?
"Why do pharmaceutical companies patent trade names for drugs as per the text?"
"Why do pharmaceutical companies patent trade names for drugs as per the text?"
What is the term used to describe when one drug diminishes the effect of another drug?
What is the term used to describe when one drug diminishes the effect of another drug?
Which term refers to the phenomenon where combining drugs increases the overall effect beyond what would be expected?
Which term refers to the phenomenon where combining drugs increases the overall effect beyond what would be expected?
Which two drugs did Heath Ledger combine that led to his death?
Which two drugs did Heath Ledger combine that led to his death?
What class of drugs is mentioned in the FDA announcement as having serious risks when combined with certain opioids?
What class of drugs is mentioned in the FDA announcement as having serious risks when combined with certain opioids?
Which term describes the phenomenon where one drug shifts the DRC to the left of another drug?
Which term describes the phenomenon where one drug shifts the DRC to the left of another drug?
What is another term for Superadditive Effect?
What is another term for Superadditive Effect?
Which of the mentioned drugs is a CNS depressant according to the FDA announcement?
Which of the mentioned drugs is a CNS depressant according to the FDA announcement?
Which organ is responsible for filtering everything from the blood and reabsorbing what is needed?
Which organ is responsible for filtering everything from the blood and reabsorbing what is needed?
What happens to lipid-soluble substances in the kidneys' filtration process?
What happens to lipid-soluble substances in the kidneys' filtration process?
How are ionized or non-lipid-soluble substances handled in the kidneys?
How are ionized or non-lipid-soluble substances handled in the kidneys?
What effect does urine acidity have on drug excretion in relation to blood pH?
What effect does urine acidity have on drug excretion in relation to blood pH?
What is responsible for the development of metabolic tolerance due to enzyme induction?
What is responsible for the development of metabolic tolerance due to enzyme induction?
Which substance is used to prevent drinking by depressing enzyme systems involved in alcohol metabolism?
Which substance is used to prevent drinking by depressing enzyme systems involved in alcohol metabolism?
How does age influence drug metabolism in young individuals?
How does age influence drug metabolism in young individuals?
Why are elderly individuals considered to have less efficient liver and kidneys regarding drug metabolism?
Why are elderly individuals considered to have less efficient liver and kidneys regarding drug metabolism?
In terms of species comparison, which species has a lower percentage of alcohol dehydrogenase activity compared to humans?
In terms of species comparison, which species has a lower percentage of alcohol dehydrogenase activity compared to humans?
What is a theoretical assumption made about the absorption curve in pharmacokinetics when no excretion is considered?
What is a theoretical assumption made about the absorption curve in pharmacokinetics when no excretion is considered?
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