Week One: Pain Management and Pharmacology
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Questions and Answers

What is the main concern for a nurse when administering medications to a client with both liver disease and chronic pain?

  • The need for increased dosages to ensure pain relief
  • The possibility of drug accumulation leading to toxicity (correct)
  • The likelihood of experiencing increased liver function tests
  • The effectiveness of opioids as a first-line treatment
  • Which medication is most appropriate for managing neuropathic pain associated with nerve damage?

  • Cyclobenzaprine for muscle relaxation
  • Hydromorphone for its opioid properties
  • Ibuprofen for its anti-inflammatory effects
  • Gabapentin as an adjuvant analgesic (correct)
  • What nursing action should be prioritized for a client experiencing sedation after receiving an opioid?

  • Immediately administer naloxone to reverse sedation
  • Instruct the client to engage in stimulating activities
  • Monitor the client's vital signs, particularly the respiratory rate (correct)
  • Document the level of sedation in the client's chart
  • What should the nurse be most vigilant about when administering acetaminophen to a client who is on warfarin?

    <p>Monitoring international normalized ratio (INR) closely</p> Signup and view all the answers

    What is the most critical nursing intervention for a client on carbamazepine who reports tremors?

    <p>Notifying the healthcare provider immediately</p> Signup and view all the answers

    What is the primary rationale for administering vitamin K in cases of salicylate poisoning?

    <p>To reverse anticoagulation effects and decrease bleeding.</p> Signup and view all the answers

    Which of the following is NOT a consequence of protein underconsumption?

    <p>Severe dehydration.</p> Signup and view all the answers

    What is the primary function of dietary fiber in human nutrition?

    <p>To aid in digestion but is largely indigestible.</p> Signup and view all the answers

    What is the role of essential fatty acids in the human body?

    <p>They support various metabolic processes crucial for overall health.</p> Signup and view all the answers

    Which type of carbohydrate is classified as a complex carbohydrate?

    <p>Starch.</p> Signup and view all the answers

    What is the most appropriate method for administering IV morphine to prioritize patient safety?

    <p>Administer over 4 to 5 minutes</p> Signup and view all the answers

    Which of the following is the minimum hourly urinary output that is expected for patients receiving opioid analgesics?

    <p>30ml/hr</p> Signup and view all the answers

    Why is buprenorphine considered inappropriate for managing breakthrough pain?

    <p>It is an agonist-antagonist that may interfere with other opioids</p> Signup and view all the answers

    What action should a nurse take when a patient's respiratory rate is below 12/min prior to opioid administration?

    <p>Withhold the medication and notify the doctor</p> Signup and view all the answers

    What is the primary objective when administering flumazenil in instances of benzodiazepine toxicity?

    <p>To reverse the effects of benzodiazepines</p> Signup and view all the answers

    What is the primary role of the sinoatrial (SA) node in the heart?

    <p>To initiate and regulate heartbeats.</p> Signup and view all the answers

    Which chamber of the heart is primarily responsible for pumping oxygenated blood into the systemic circulation?

    <p>Left ventricle</p> Signup and view all the answers

    Which coronary artery supplies the left atrium and the lateral surfaces of the left ventricle?

    <p>Circumflex artery</p> Signup and view all the answers

    What characterizes the third heart sound (S3) in a patient?

    <p>Is normal in individuals younger than 30 years</p> Signup and view all the answers

    What is the effect of sympathetic stimulation on the heart rate?

    <p>Increases heart rate and conduction speed</p> Signup and view all the answers

    What occurs during the relaxation phase of the heart in relation to the semilunar valves?

    <p>The semilunar valves prevent blood from flowing back into the ventricles.</p> Signup and view all the answers

    What causes the fourth heart sound (S4) to be heard during atrial systole?

    <p>Ventricular hypertrophy or wall injury</p> Signup and view all the answers

    What is the normal range for total cholesterol according to cardiovascular diagnostic procedures?

    <p>Less than 200 mg/dL</p> Signup and view all the answers

    Which cardiac enzyme is primarily used to diagnose myocardial infarction and is released into the bloodstream upon heart injury?

    <p>Troponin I</p> Signup and view all the answers

    Which parameter does mixed venous oxygen saturation (SvO2) measure?

    <p>Oxygen supply versus demand balance</p> Signup and view all the answers

    What is the position recommended for a patient during the insertion of a pulmonary artery catheter?

    <p>Supine or Trendelenburg position</p> Signup and view all the answers

    Which condition typically results in high-output heart failure?

    <p>Septicemia</p> Signup and view all the answers

    Which action is crucial immediately following an exercise stress test for a patient?

    <p>Monitoring vital signs and blood pressure closely</p> Signup and view all the answers

    What dietary consideration is critical for patients at risk of heart failure?

    <p>Fluid restrictions</p> Signup and view all the answers

    Which example is NOT a common manifestation of left-sided heart failure?

    <p>Jugular vein distention</p> Signup and view all the answers

    Which medication is classified as a high-ceiling loop diuretic effective even in renal impairment?

    <p>Furosemide</p> Signup and view all the answers

    What is the primary mechanism by which Class III antidysrhythmic medications exert their effects?

    <p>Prolonging the action potential and refractory period</p> Signup and view all the answers

    What effect do beta-adrenergic blockers have on cardiac function?

    <p>They prevent cardiac stimulation by sympathetic signals.</p> Signup and view all the answers

    What is a primary concern when using antidysrhythmic medications?

    <p>Medication toxicity resulting in cardiac dysrhythmias</p> Signup and view all the answers

    Which symptom should a nurse instruct a client to report while taking furosemide?

    <p>Tinnitus</p> Signup and view all the answers

    What is a potential serious adverse reaction to ACE inhibitors that requires immediate medical attention?

    <p>Angioedema</p> Signup and view all the answers

    What contraindication is associated with using diltiazem?

    <p>Hypotension</p> Signup and view all the answers

    Which finding indicates digoxin toxicity?

    <p>Cardiac arrhythmias</p> Signup and view all the answers

    What is the primary effect of thiazide diuretics like HCTZ when treating diabetes insipidus?

    <p>Reduce urine production by 30 to 50%</p> Signup and view all the answers

    What distinguishes the point of origin from the point of insertion in skeletal muscles?

    <p>The origin does not move, while the insertion does during contraction.</p> Signup and view all the answers

    What potential complication should be monitored closely for patients on long-term ibuprofen therapy?

    <p>Cardiovascular irregularities</p> Signup and view all the answers

    What is the primary reason why buprenorphine is not suitable for managing breakthrough pain?

    <p>It has limited efficacy due to its agonist-antagonist properties</p> Signup and view all the answers

    What action should a nurse take for a patient with a respiratory rate below 12/min prior to the administration of opioids?

    <p>Withhold the opioid and communicate with the doctor</p> Signup and view all the answers

    In a vaso-occlusive crisis with flexed knees and hips, what main outcome should a nurse be cautious about?

    <p>Diminished perfusion leading to increased pain</p> Signup and view all the answers

    After administering hydromorphone, when is the most critical period for assessing a patient's pain level for effective management?

    <p>30 minutes to 1 hour post-administration</p> Signup and view all the answers

    Which pharmacological approach is critical for managing anxiety symptoms during alcohol detoxification?

    <p>Prescribing diazepam to alleviate withdrawal effects</p> Signup and view all the answers

    What key nursing action should be taken for a client on carbamazepine who is experiencing tremors?

    <p>Reporting the tremors to the prescribing provider immediately</p> Signup and view all the answers

    Which type of pain management strategy should the nurse use for a client with chronic arthritis pain?

    <p>Recommending celecoxib while also monitoring for cardiovascular risks</p> Signup and view all the answers

    What primary consideration should a nurse remember when administering acetaminophen to a patient on warfarin?

    <p>Monitoring the patient's INR closely is essential</p> Signup and view all the answers

    Which nursing consideration is essential for a patient prescribed dexamethasone?

    <p>Reducing the dosage gradually over time before stopping</p> Signup and view all the answers

    Study Notes

    Acute and Cancer Pain Management

    • Administer IV morphine over 4 to 5 minutes to ensure patient safety.
    • Minimum expected urinary output for patients on opioid analgesics is 30 ml/hr.
    • Buprenorphine is unsuitable for breakthrough pain as it may interfere with other opioids.
    • Withhold opioids when respiratory rate is below 12/min and notify the doctor.
    • Flumazenil is primarily used to reverse benzodiazepine toxicity.
    • Assess pain level 30 minutes to 1 hour after administering hydromorphone for effective management.

    Complications and Monitoring

    • Caution for diminished perfusion in patients with severe pain during vaso-occlusive crises.
    • Monitor patients on long-term ibuprofen therapy for gastrointestinal bleeding and tinnitus.
    • Notify the doctor for dosage adjustment if breakthrough pain occurs despite opioid administration.
    • Diazepam is prescribed during alcohol detoxification mainly to alleviate anxiety and minimize withdrawal effects.

    Medication Management

    • Hold naproxen for patients with chronic kidney disease and consult with prescriber.
    • Warn patients on celecoxib of the increased risk for heart attack and stroke.
    • Monitor respiratory rate closely for clients who develop sedation after opioid administration.
    • Rapid notification of a provider is crucial for patients on carbamazepine exhibiting tremors.

    Pediatric and Special Populations Considerations

    • Naloxone is the recommended treatment for acute narcotic toxicity in newborns.
    • Monitor INR closely when administering acetaminophen to patients on warfarin.
    • Fentanyl users require careful observation of respiratory rate.
    • Encourage monitoring for opioid withdrawal signs in patients prescribed butorphanol.

    Nutrition Essentials

    • Carbohydrates primarily supply energy for the body, with a minimum daily intake of 130 g for brain function.
    • Dietary fiber aids digestion but is indigestible, and its intake is crucial for metabolic health.
    • Complementary proteins, when combined, provide a complete protein profile necessary for health.
    • Essential fatty acids are vital for metabolic processes and blood clotting.

    Child Nutrition Guidelines

    • Toddlers aged 1 to 3 should limit 100% juice intake to 4 to 6 oz and milk consumption to 24 oz daily.
    • Foods that pose choking risks, like nuts, should be avoided for toddlers.
    • School-age children may develop unhealthy eating behaviors, such as snacking out of boredom.

    Adolescent Dietary Needs

    • Females typically experience a growth spurt starting at age 10 with increased dietary iron requirements.
    • Maximum calcium intake for adolescents is recommended at 1,300 mg/day.

    Cardiovascular Physiology

    • The AV node can maintain a heart rate of 40 to 60 bpm if the SA node fails.
    • Sympathetic stimulation increases both heart rate and conduction speed.
    • The circumflex artery supplies blood to the left atrium and lateral surfaces of the left ventricle.

    Cardiac Structure and Function

    • Sinus heart rate is typically between 60 to 100 bpm.
    • The myocardium is responsible for heart contraction while the endocardium lines the heart chambers.
    • The tricuspid valve prevents backflow into the right atrium.
    • The SA node regulates heartbeats by initiating impulses, essential for coordinating heart function.

    Pericardium and Heart Valves

    • The visceral pericardium protects and lubricates the heart, whereas the parietal pericardium anchors the heart.
    • During heart relaxation, semilunar valves prevent backflow into the ventricles, ensuring unidirectional blood flow.
    • The left ventricle pumps oxygenated blood into systemic circulation, crucial for delivering oxygen throughout the body.### Cardiac Diagnostic Tests and Procedures
    • Normal pericardial fluid: Typically found volume is 5 to 20 mL.
    • Lipid profile fasting duration: Recommended to fast for 12 to 14 hours before sampling.
    • Myocardial infarction enzyme: Troponin I is the primary enzyme released into the bloodstream during heart muscle injury.
    • Lipid profile purpose: Provides information about cholesterol levels, crucial for cardiovascular health assessments.
    • Transthoracic echocardiogram: Used to diagnose valve disorders and evaluate heart structure.
    • Normal cholesterol range: Considered less than 200 mg/dL according to cardiovascular diagnostic guidelines.
    • Transesophageal echocardiography: Client should be instructed to be NPO (nothing by mouth) for 4 to 6 hours before the procedure.
    • Hemodynamic monitoring indications: Not indicated for mild atrial fibrillation; relevant in heart failure, post-CABG, and critical illnesses.

    Patient Management and Observations

    • Pulmonary artery catheter positioning: Patient should be placed in the supine or Trendelenburg position during insertion.
    • Mixed venous oxygen saturation (SvO2): Measures the balance between oxygen supply and demand in the body.
    • Immediate post-exercise stress test care: Vital signs and blood pressure should be monitored closely after the procedure.
    • Diastolic heart failure: Primarily results in inadequate left ventricle output and inadequate tissue perfusion.
    • ACC/AHA Stage B: Refers to patients with cardiac structural abnormalities without heart failure manifestations.
    • NYHA Class IV: Indicates a patient experiencing manifestations of heart failure at rest.
    • Pulmonary edema: Associated with left-sided heart failure, leading to accumulation in lung tissue.

    Heart Failure and Medications

    • Common consequence of right-sided heart failure: Peripheral edema is a notable symptom.
    • High-output heart failure is typically seen in conditions like septicemia.
    • Left-sided heart failure symptoms: Include fatigue, frothy sputum, and nocturnal dyspnea, while jugular vein distention is not common.
    • Heart failure severity test: B-type natriuretic peptides (BNP) provide direct evidence of heart failure intensity.
    • Diuretic therapy: High-ceiling loop diuretics like furosemide are effective even in renal impairment.
    • Monitor for hypotension: A common complication from using loop diuretics when changing positions.

    Electrolytes, Nutritional Considerations, and Monitoring

    • Electrolyte monitoring: Essential for detecting efficacy and avoiding complications when clients are on loop diuretics.
    • Dietary considerations for heart failure: Fluid restriction is critical, while a high-sodium diet should be avoided.
    • Common hypokalemia symptoms: Include nausea, fatigue, and leg cramps, but muscle twitching is not typically associated.

    Antidysrhythmic Medications

    • Class III antidysrhythmics effect: Prolong the action potential and refractory period of cardiac tissue.
    • Beta-adrenergic blockers function: Prevent sympathetic stimulation of the heart, lowering heart rate and reducing cardiac workload.
    • Calcium channel blockers: Reduce myocardial excitability and depress conduction to manage dysrhythmias.

    Anesthesia and Surgical Considerations

    • General anesthesia: Involves complete muscle relaxation; risks include the potential for malignant hyperthermia, especially in those with a genetic predisposition.
    • Moderate sedation: Allows patients to remain arousable to verbal stimuli, with continuous monitoring being crucial.
    • Post-operative monitoring: Maintaining airway patency is the top priority while managing anesthesia during surgery.
    • Malignant hyperthermia: Requires immediate intervention with cooled intravenous saline and is indicated by symptoms such as muscle rigidity and elevated body temperature.

    Musculoskeletal System Insights

    • Spongy bone functionality: Better at withstand multi-directional forces, primarily found at bone ends.
    • Skeletal muscle origin and insertion: The origin remains fixed while the insertion moves during contraction.
    • Bone healing stages: Include hematoma formation, callus formation, and bone remodeling; necrotic tissue clearance is not a recognized stage.

    Imaging and Diagnostic Procedures

    • MRI preparation: Check for metal implants due to magnetic properties.
    • Synovial fluid role: Lubricates joints, absorbs shock, and transports nutrients to bone structures.
    • Bone scan purpose: Identifies and stages bone cancer; not invasive.

    Fractures and Management Strategies

    • RICE method: Common management for sprains involves Rest, Ice, Compression, and Elevation.
    • Skin traction: Involves non-invasive methods like elastic bandages for stabilization.
    • Essential post-fracture reduction goal: Restoring proper alignment of the bone.

    Complications and Patient Education

    • Opioids during anesthesia: Adverse effects include respiratory depression and nausea; clients should be educated to report any significant side effects.
    • Signs of systemic toxicity from local anesthesia: Increased heart rate is common and should be closely monitored.### Beta-Adrenergic Agonists
    • Beta2 Agonist Usage: Albuterol is categorized as a Short-Acting Beta2 Agonist (SABA), primarily indicated for quick relief in asthma management.
    • Common Side Effects: Tachycardia is a notable side effect from oral beta2 adrenergic agonists, necessitating monitoring of heart rate.
    • Long-Term Control: Formoterol is utilized for long-term asthma control, highlighting its importance in chronic management.
    • Nursing Actions: Check for significant pulse increases in patients taking beta2 adrenergic agonists and report any anomalies.

    Theophylline and Its Monitoring

    • Therapeutic Action: Theophylline acts as a bronchodilator by relaxing bronchial smooth muscles.
    • Toxicity Signs: Moderate to severe toxicity from theophylline can cause dysrhythmias and seizures, indicating need for careful monitoring.
    • Complications from Beclomethasone: Beclomethasone can lead to hoarseness, a complication requiring patient education.

    Glucocorticoids Administration

    • Monitoring: For clients on oral glucocorticoids for an extended period (10 days or longer), monitor for signs of adrenal suppression.
    • Patient Education: Advise patients on prednisone to be aware of nystatin for candidiasis treatment.

    Tuberculosis (TB) Management

    • Active Symptoms: A persistent cough is a key symptom of active tuberculosis.
    • Screening Priority: Family members of infected individuals should be prioritized for tuberculosis screening to contain potential outbreaks.
    • Testing Techniques: Sputum samples for TB must be collected in a negative airflow room.

    Respiratory System Functions

    • Surfactant Role: Surfactant in the alveoli reduces surface tension, preventing alveolar collapse during respiration.
    • Inspiration Mechanism: The phrenic nerve is responsible for diaphragm contraction, allowing breathing to occur.
    • Alveoli Purpose: Alveoli serve as the basic units for gas exchange within the respiratory system.

    Anticoagulants and Their Monitoring

    • Warfarin Management: Warfarin requires routine monitoring of PT and INR to adjust dosing, with a therapeutic INR range of 2 to 3.
    • Direct Thrombin Inhibitors: Dabigatran etexilate is classified as a direct thrombin inhibitor used for anticoagulation.
    • Monitoring Precautions: Monitoring vital signs is crucial during thrombolytic therapy to identify potential bleeding complications.

    Cardiac Medications

    • Inotropic Medication Monitoring: Continuous monitoring of blood pressure and heart rate is essential when administering positive inotropic medications.
    • Digoxin Side Effects: Visual disturbances, such as yellow vision, are closely associated with digoxin therapy, indicating potential toxicity.
    • Antiplatelet Contradictions: History of gastrointestinal bleeding is a contraindication for antiplatelet medication use, cautioning prescribers in these situations.

    Acute and Cancer Pain Management

    • Administer IV morphine over 4 to 5 minutes to ensure patient safety.
    • Minimum expected urinary output for patients on opioid analgesics is 30 ml/hr.
    • Buprenorphine is unsuitable for breakthrough pain as it may interfere with other opioids.
    • Withhold opioids when respiratory rate is below 12/min and notify the doctor.
    • Flumazenil is primarily used to reverse benzodiazepine toxicity.
    • Assess pain level 30 minutes to 1 hour after administering hydromorphone for effective management.

    Complications and Monitoring

    • Caution for diminished perfusion in patients with severe pain during vaso-occlusive crises.
    • Monitor patients on long-term ibuprofen therapy for gastrointestinal bleeding and tinnitus.
    • Notify the doctor for dosage adjustment if breakthrough pain occurs despite opioid administration.
    • Diazepam is prescribed during alcohol detoxification mainly to alleviate anxiety and minimize withdrawal effects.

    Medication Management

    • Hold naproxen for patients with chronic kidney disease and consult with prescriber.
    • Warn patients on celecoxib of the increased risk for heart attack and stroke.
    • Monitor respiratory rate closely for clients who develop sedation after opioid administration.
    • Rapid notification of a provider is crucial for patients on carbamazepine exhibiting tremors.

    Pediatric and Special Populations Considerations

    • Naloxone is the recommended treatment for acute narcotic toxicity in newborns.
    • Monitor INR closely when administering acetaminophen to patients on warfarin.
    • Fentanyl users require careful observation of respiratory rate.
    • Encourage monitoring for opioid withdrawal signs in patients prescribed butorphanol.

    Nutrition Essentials

    • Carbohydrates primarily supply energy for the body, with a minimum daily intake of 130 g for brain function.
    • Dietary fiber aids digestion but is indigestible, and its intake is crucial for metabolic health.
    • Complementary proteins, when combined, provide a complete protein profile necessary for health.
    • Essential fatty acids are vital for metabolic processes and blood clotting.

    Child Nutrition Guidelines

    • Toddlers aged 1 to 3 should limit 100% juice intake to 4 to 6 oz and milk consumption to 24 oz daily.
    • Foods that pose choking risks, like nuts, should be avoided for toddlers.
    • School-age children may develop unhealthy eating behaviors, such as snacking out of boredom.

    Adolescent Dietary Needs

    • Females typically experience a growth spurt starting at age 10 with increased dietary iron requirements.
    • Maximum calcium intake for adolescents is recommended at 1,300 mg/day.

    Cardiovascular Physiology

    • The AV node can maintain a heart rate of 40 to 60 bpm if the SA node fails.
    • Sympathetic stimulation increases both heart rate and conduction speed.
    • The circumflex artery supplies blood to the left atrium and lateral surfaces of the left ventricle.

    Cardiac Structure and Function

    • Sinus heart rate is typically between 60 to 100 bpm.
    • The myocardium is responsible for heart contraction while the endocardium lines the heart chambers.
    • The tricuspid valve prevents backflow into the right atrium.
    • The SA node regulates heartbeats by initiating impulses, essential for coordinating heart function.

    Pericardium and Heart Valves

    • The visceral pericardium protects and lubricates the heart, whereas the parietal pericardium anchors the heart.
    • During heart relaxation, semilunar valves prevent backflow into the ventricles, ensuring unidirectional blood flow.
    • The left ventricle pumps oxygenated blood into systemic circulation, crucial for delivering oxygen throughout the body.### Cardiac Health and Diagnostics
    • Typical pericardial fluid volume ranges from 5 to 20 mL.
    • Recommended fasting duration for a lipid profile is 12 to 14 hours.
    • Troponin I is the primary cardiac enzyme used for diagnosing myocardial infarctions.
    • A lipid profile primarily assesses cholesterol levels.
    • A transthoracic echocardiogram is used to diagnose valve disorders and evaluate heart structure.
    • Normal total cholesterol levels are considered to be less than 200 mg/dL.
    • Patients should be NPO (nothing by mouth) for 4 to 6 hours prior to transesophageal echocardiography.

    Heart Failure and Monitoring

    • Mild atrial fibrillation is not an indication for hemodynamic monitoring.
    • Patients during pulmonary artery catheter insertion should be positioned supine or in Trendelenburg position.
    • Mixed venous oxygen saturation (SvO2) measures the balance between oxygen supply and demand.
    • Post-exercise stress test, monitoring the patient's vital signs closely is crucial.
    • Diastolic heart failure leads to inadequate left ventricle output and tissue perfusion.

    Classification and Symptoms

    • American College of Cardiology and American Heart Association Stage B indicates structural abnormalities without heart failure manifestations.
    • In the New York Heart Association classification, Class IV indicates manifestations at rest.
    • Left-sided heart failure may lead to pulmonary edema.

    Diuretics and Electrolyte Management

    • Right-sided heart failure commonly results in peripheral edema.
    • High-output heart failure is often caused by septicemia.
    • Jugular vein distention is not commonly associated with left-sided heart failure.
    • B-type natriuretic peptides (BNP) serve as direct indicators of heart failure severity.
    • Increased central venous pressure (CVP) is expected in heart failure cases.

    Medication Management

    • Diuretics may require dietary fluid restrictions for patients at risk of heart failure.
    • Furosemide is classified as a high-ceiling loop diuretic, effective even in renal impairment.
    • Hypotension can result from using high-ceiling loop diuretics.
    • High-ceiling loop diuretics are not typically used for treating hypocalcemia.
    • Monitoring daily weight is crucial for patients receiving high-ceiling loop diuretics to prevent dehydration.

    Symptoms and Toxicity

    • Symptoms of hypokalemia do not typically include muscle twitching.
    • Digoxin toxicity can occur in patients with hypokalemia.
    • Thiazide diuretics are contraindicated in renal impairment.
    • Electrolyte levels must be monitored in patients on loop diuretics for efficacy and to avoid complications.

    Antidysrhythmic Medications

    • Class III antidysrhythmic medications like Amiodarone prolong the action potential and refractory period.
    • Class IA sodium channel blockers are correctly represented by Quinidine.
    • Beta-adrenergic blockers prevent sympathetic signals' stimulation on cardiac function.
    • Medication toxicity resulting in dysrhythmias is a primary concern when using antidysrhythmic medications.
    • Calcium channel blockers reduce conduction and depress depolarization in the heart.

    Surgical and Anesthesia Considerations

    • General anesthesia is suitable for major surgeries requiring complete muscle relaxation, with a risk factor of malignant hyperthermia.
    • Moderate sedation allows clients to be arousable to verbal stimuli.
    • The main priority during anesthesia management is maintaining airway patency.
    • Propofol is contraindicated in patients allergic to eggs and soybean oil.
    • Stage IV general anesthesia is characterized by fixed pupils and a risk of respiratory failure.

    Bone Health and Musculoskeletal Considerations

    • Spongy bone is found primarily at the ends of long bones and can withstand multi-directional forces.
    • The point of origin in skeletal muscles is stationary during contraction, while the insertion is movable.
    • Ossification in epiphyseal cartilage continues until around age 25, affecting bone growth.
    • A simple fracture maintains intact skin over the fractured area, with no soft tissue injury.

    Imaging and Rehabilitation

    • A bone scan is used to identify bone cancer and detect fractures.
    • Post-bone scan, encouraging oral fluid intake is vital for renal filtering.
    • The RICE method (Rest, Ice, Compression, Elevation) is commonly used for managing sprains.

    Pain and Recovery Management

    • Monitoring vital signs is essential for managing anesthesia in surgical situations.
    • Systemic toxicity from local anesthesia can lead to increased heart rate.
    • Malignant hyperthermia may manifest late with an extremely elevated temperature.
    • Essential nursing action during malignant hyperthermia is to infuse iced IV 0.9% sodium chloride.### Pharmacology of Respiratory Medications
    • Beta2 agonists like Albuterol are categorized as Short-Acting Beta2 Agonists (SABA) used for immediate relief in asthma.
    • Common side effect of oral beta2 adrenergic agonists is tachycardia; monitoring is essential.
    • Formoterol is primarily indicated for long-term asthma control.
    • Nursing actions include checking pulse to observe significant increases when using beta2 adrenergic agonists.
    • Theophylline acts by inducing bronchodilation through bronchial smooth muscle relaxation.

    Medication Contraindications and Side Effects

    • Long-acting beta2 agonists are contraindicated for clients with tachydysrhythmia.
    • Theophylline toxicity can lead to dysrhythmias and seizures.
    • Side effects of inhaled anticholinergics can be managed by sucking on sugar-free hard candies to alleviate dry mouth.
    • Beclomethasone use can cause hoarseness as a potential complication.

    Glucocorticoid Therapy and Considerations

    • Prolonged use of oral glucocorticoids requires monitoring for adrenal suppression.
    • Prednisone should not be administered on an as-needed basis; education on this medication is crucial.
    • Increase glucocorticoid dosage during periods of respiratory infection for effective management.
    • Prednisone is contraindicated in individuals with systemic fungal infections.

    Management of Asthma and Allergies

    • Montelukast is a leukotriene modifier indicated for children starting from 12 months.
    • Risks associated with montelukast usage include depression and suicidal ideation.
    • For zileuton, baseline liver function tests are crucial before administration.

    Tuberculosis (TB) Infection and Screening

    • Latent TB means Mycobacterium tuberculosis is present asymptomatically.
    • A persistent cough is a common symptom of active tuberculosis infection.
    • Screening should prioritize family members of infected individuals for transmission risk.
    • The QuantiFERON-TB Gold test is the most rapid and accurate laboratory test to confirm TB presence.

    Respiratory System Functionality

    • Surfactant in alveoli reduces surface tension, preventing collapse.
    • The phrenic nerve is fundamentally responsible for the inspiration process.
    • During inspiration, the diaphragm contracts and descends into the abdominal cavity.

    Sputum Testing and Patient Management

    • Sputum samples for TB must be collected in a negative airflow room.
    • Mantoux test evaluates immune response to TB exposure rather than confirming active disease.
    • The primary function of the respiratory system includes the removal of carbon dioxide from the body.

    Anticoagulants and Thrombolytic Medications

    • Warfarin sodium requires routine monitoring of PT and INR for dosing adjustments.
    • Therapeutic INR range for warfarin is 2 to 3 for effective anticoagulation.
    • Dabigatran etexilate is recognized as a direct thrombin inhibitor.
    • Monitoring vital signs during thrombolytic therapy is critical to detect bleeding complications.

    Patient Safety and Medication Interventions

    • For patients on anticoagulants, advising on bleeding precautions is paramount.
    • Conditions like active bleeding contraindicate anticoagulant therapy.
    • Subcutaneous heparin should be given at a 90-degree angle in the abdomen.

    Cardiac Medications and Care

    • Antiplatelet medications prevent platelet aggregation, prolonging bleeding time.
    • Close monitoring of blood pressure and heart rate is necessary when administering positive inotropic medications.
    • Visual disturbances, like yellow vision, are closely associated with digoxin therapy.
    • Cardiac glycosides require caution in patients with renal disease or electrolyte imbalances.

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    This quiz focuses on acute pain management, cancer pain, and the pharmacological principles relevant to these conditions. Participants will test their knowledge on safe administration practices and expected outcomes for patients receiving opioid analgesics. Prepare to enhance your understanding of pain management and pharmacology.

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