26 Questions
What is the primary cause of malignant hyperthermia?
Genetic mutation, often hereditary
What is the result of rhabdomyolysis on the kidneys?
Acute renal failure
What is the diagnostic marker for rhabdomyolysis?
Enzyme level reaching about 1000 units/L
What is the primary goal of treating rhabdomyolysis?
Preventing kidney failure and maintaining adequate urinary output
What is the characteristic triad of manifestations of rhabdomyolysis?
Muscle pain, weakness, and dark urine
What is the significance of the MHS gene in relation to malignant hyperthermia?
It is a gene that can be tested for to predict malignant hyperthermia
Which type of arthritis is characterized by wear and tear, causing cartilage damage and bone restructuring?
Osteoarthritis
What is the primary risk factor for Osteomalacia?
Vitamin D deficiency
Which of the following is a clinical manifestation of Rheumatoid Arthritis?
All of the above
What is the term for the loss of ability of tissues to perform/function as intended?
Contractures
Which of the following is a risk factor for Osteoporosis?
Hormonal imbalance
What is the term for the muscle shrinkage that results in decreased muscle mass/density?
Muscle atrophy
What is the term for the increased pressure within a muscle compartment?
Compartment Syndrome
What is the severe allergic reaction to anesthetics?
Malignant Hyperthermia
What are the clinical manifestations of Compartment Syndrome?
6 P's
Which of the following is NOT a risk factor for Osteoporosis?
Vitamin C deficiency
What is the primary characteristic of fibromyalgia?
Increased sensitivity to touch and unexplained pain
What is the name of the disease that results from the breakdown of purines, often associated with red meats and alcohol?
Gout
What is the term for the presence of tophi in the body?
Tophaceous gout
What is the name of the disease that affects the spine or sacroiliac joints, resulting in stiffening and fusion of those joints?
Ankylosing Spondylitis
What is the term for the reduction in the normal size of muscle fibers as a result of prolonged inactivity?
Disuse atrophy
What is the name of the disease that results from the chronic accelerated, disordered bone remodeling?
Paget Disease of Bone
What is the term for the process of bone healing that occurs when surgical fixation is used to repair a broken bone?
Direct (primary) healing
What is the name of the disease that is characterized by a seemingly depressive state, profound fatigue, pain, and impaired sleep?
Chronic Fatigue Syndrome
What is the term for the inflammatory response that occurs in the joints, characterized by warmth, redness, and pain?
Acute inflammation
What is the term for the fracture that is not only broken but also splintered?
Comminuted fracture
Review the basics of musculoskeletal pathophysiology, including types of arthritis, osteoarthritis, and its causes and effects on joints. This quiz covers the fundamentals of joint damage and restructuring, including Heberden and Bouchard nodes.
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