Week 11: Musculoskeletal Pathophysiology - Arthritis and Osteoarthritis
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Questions and Answers

What is the primary cause of malignant hyperthermia?

  • A side effect of chronic fatigue
  • Genetic mutation, often hereditary (correct)
  • An allergic reaction to anesthetics
  • Muscle breakdown due to fever

What is the result of rhabdomyolysis on the kidneys?

  • Muscle weakness
  • Electrolyte imbalance
  • Acute renal failure (correct)
  • Chronic kidney disease

What is the diagnostic marker for rhabdomyolysis?

  • Blood urea nitrogen level above 20
  • Creatine kinase level above 500 units/L
  • White blood cell count above 10,000
  • Enzyme level reaching about 1000 units/L (correct)

What is the primary goal of treating rhabdomyolysis?

<p>Preventing kidney failure and maintaining adequate urinary output (A)</p> Signup and view all the answers

What is the characteristic triad of manifestations of rhabdomyolysis?

<p>Muscle pain, weakness, and dark urine (C)</p> Signup and view all the answers

What is the significance of the MHS gene in relation to malignant hyperthermia?

<p>It is a gene that can be tested for to predict malignant hyperthermia (B)</p> Signup and view all the answers

Which type of arthritis is characterized by wear and tear, causing cartilage damage and bone restructuring?

<p>Osteoarthritis (A)</p> Signup and view all the answers

What is the primary risk factor for Osteomalacia?

<p>Vitamin D deficiency (D)</p> Signup and view all the answers

Which of the following is a clinical manifestation of Rheumatoid Arthritis?

<p>All of the above (D)</p> Signup and view all the answers

What is the term for the loss of ability of tissues to perform/function as intended?

<p>Contractures (B)</p> Signup and view all the answers

Which of the following is a risk factor for Osteoporosis?

<p>Hormonal imbalance (B)</p> Signup and view all the answers

What is the term for the muscle shrinkage that results in decreased muscle mass/density?

<p>Muscle atrophy (B)</p> Signup and view all the answers

What is the term for the increased pressure within a muscle compartment?

<p>Compartment Syndrome (A)</p> Signup and view all the answers

What is the severe allergic reaction to anesthetics?

<p>Malignant Hyperthermia (C)</p> Signup and view all the answers

What are the clinical manifestations of Compartment Syndrome?

<p>6 P's (A)</p> Signup and view all the answers

Which of the following is NOT a risk factor for Osteoporosis?

<p>Vitamin C deficiency (A)</p> Signup and view all the answers

What is the primary characteristic of fibromyalgia?

<p>Increased sensitivity to touch and unexplained pain (C)</p> Signup and view all the answers

What is the name of the disease that results from the breakdown of purines, often associated with red meats and alcohol?

<p>Gout (B)</p> Signup and view all the answers

What is the term for the presence of tophi in the body?

<p>Tophaceous gout (A)</p> Signup and view all the answers

What is the name of the disease that affects the spine or sacroiliac joints, resulting in stiffening and fusion of those joints?

<p>Ankylosing Spondylitis (A)</p> Signup and view all the answers

What is the term for the reduction in the normal size of muscle fibers as a result of prolonged inactivity?

<p>Disuse atrophy (B)</p> Signup and view all the answers

What is the name of the disease that results from the chronic accelerated, disordered bone remodeling?

<p>Paget Disease of Bone (A)</p> Signup and view all the answers

What is the term for the process of bone healing that occurs when surgical fixation is used to repair a broken bone?

<p>Direct (primary) healing (D)</p> Signup and view all the answers

What is the name of the disease that is characterized by a seemingly depressive state, profound fatigue, pain, and impaired sleep?

<p>Chronic Fatigue Syndrome (C)</p> Signup and view all the answers

What is the term for the inflammatory response that occurs in the joints, characterized by warmth, redness, and pain?

<p>Acute inflammation (B)</p> Signup and view all the answers

What is the term for the fracture that is not only broken but also splintered?

<p>Comminuted fracture (D)</p> Signup and view all the answers

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