Week 11: Musculoskeletal Pathophysiology - Arthritis and Osteoarthritis
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Questions and Answers

What is the primary cause of malignant hyperthermia?

  • A side effect of chronic fatigue
  • Genetic mutation, often hereditary (correct)
  • An allergic reaction to anesthetics
  • Muscle breakdown due to fever

    • What is the result of rhabdomyolysis on the kidneys?

  • Muscle weakness
  • Electrolyte imbalance
  • Acute renal failure (correct)
  • Chronic kidney disease

    • What is the diagnostic marker for rhabdomyolysis?

  • Blood urea nitrogen level above 20
  • Creatine kinase level above 500 units/L
  • White blood cell count above 10,000
  • Enzyme level reaching about 1000 units/L (correct)

    • What is the primary goal of treating rhabdomyolysis?

    <p>Preventing kidney failure and maintaining adequate urinary output</p> Signup and view all the answers

    What is the characteristic triad of manifestations of rhabdomyolysis?

    <p>Muscle pain, weakness, and dark urine</p> Signup and view all the answers

    What is the significance of the MHS gene in relation to malignant hyperthermia?

    <p>It is a gene that can be tested for to predict malignant hyperthermia</p> Signup and view all the answers

    Which type of arthritis is characterized by wear and tear, causing cartilage damage and bone restructuring?

    <p>Osteoarthritis</p> Signup and view all the answers

    What is the primary risk factor for Osteomalacia?

    <p>Vitamin D deficiency</p> Signup and view all the answers

    Which of the following is a clinical manifestation of Rheumatoid Arthritis?

    <p>All of the above</p> Signup and view all the answers

    What is the term for the loss of ability of tissues to perform/function as intended?

    <p>Contractures</p> Signup and view all the answers

    Which of the following is a risk factor for Osteoporosis?

    <p>Hormonal imbalance</p> Signup and view all the answers

    What is the term for the muscle shrinkage that results in decreased muscle mass/density?

    <p>Muscle atrophy</p> Signup and view all the answers

    What is the term for the increased pressure within a muscle compartment?

    <p>Compartment Syndrome</p> Signup and view all the answers

    What is the severe allergic reaction to anesthetics?

    <p>Malignant Hyperthermia</p> Signup and view all the answers

    What are the clinical manifestations of Compartment Syndrome?

    <p>6 P's</p> Signup and view all the answers

    Which of the following is NOT a risk factor for Osteoporosis?

    <p>Vitamin C deficiency</p> Signup and view all the answers

    What is the primary characteristic of fibromyalgia?

    <p>Increased sensitivity to touch and unexplained pain</p> Signup and view all the answers

    What is the name of the disease that results from the breakdown of purines, often associated with red meats and alcohol?

    <p>Gout</p> Signup and view all the answers

    What is the term for the presence of tophi in the body?

    <p>Tophaceous gout</p> Signup and view all the answers

    What is the name of the disease that affects the spine or sacroiliac joints, resulting in stiffening and fusion of those joints?

    <p>Ankylosing Spondylitis</p> Signup and view all the answers

    What is the term for the reduction in the normal size of muscle fibers as a result of prolonged inactivity?

    <p>Disuse atrophy</p> Signup and view all the answers

    What is the name of the disease that results from the chronic accelerated, disordered bone remodeling?

    <p>Paget Disease of Bone</p> Signup and view all the answers

    What is the term for the process of bone healing that occurs when surgical fixation is used to repair a broken bone?

    <p>Direct (primary) healing</p> Signup and view all the answers

    What is the name of the disease that is characterized by a seemingly depressive state, profound fatigue, pain, and impaired sleep?

    <p>Chronic Fatigue Syndrome</p> Signup and view all the answers

    What is the term for the inflammatory response that occurs in the joints, characterized by warmth, redness, and pain?

    <p>Acute inflammation</p> Signup and view all the answers

    What is the term for the fracture that is not only broken but also splintered?

    <p>Comminuted fracture</p> Signup and view all the answers

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