PRE-TEST_Clinical Chemistry

Factor to convert IMMUNOGLOBULIN value from mg/dL to g/L:

Heparin is added ___ per mL of blood in each test tube.

A blood sample is left on a phlebotomy tray for 4.5 hours before it is delivered to the laboratory. Which group of tests could be performed?

What is used to zero the spectrophotometer BEFORE reading the test sample?

This is used to zero an instrument DURING a test procedure:

Type 3c diabetes, EXCEPT:

Creatine is synthesized in the liver from all of the following amino acids, EXCEPT:

It transports protein for thyroxine and triiodothyronine (thyroid hormones); it also binds with retinol-binding protein to form a complex that transports retinol (vitamin A):

A low ___ level is a sensitive marker of poor nutritional status.

Which of the following would be most adversely affected by a nonfasting sample?

Which of the following lipid tests is least affected by the fasting status of the patient?

Major roles of ___ is to maintain the equilibrium of cholesterol in peripheral cells by the REVERSE CHOLESTEROL TRANSPORT pathway:

Rare autosomal recessive disorder characterized by complete absence of HDL:

Abetalipoproteinemia is also known as:

If left unprotected from light, bilirubin values may reduce by ___ per hour.

The "gold standard" in the diagnosis of acute coronary syndrome (ACS):

If elevated, which laboratory test would support a diagnosis of CONGESTIVE HEART FAILURE?

ALP isoenzyme that will resist heat denaturation at 65°C for 30 minutes:

Which of the following buffers is used in the IFCC recommended method for ALP?

Assay methods for AST are generally based on the principle of the Karmen method, which incorporates a coupled enzymatic reaction using:

Given the following results:

• ALP: marked increased
• AST: slight increased
• ALT: slight increased
• GGT: marked increased This is most consistent with:

A physician orders several laboratory tests on a 55-year-old male patient who is complaining of pain, stiffness, fatigue and headaches. Based on the following serum test results, what is the most likely diagnosis?

• ALP: significantly increased
• GGT: normal

42-year-old male presents with anorexia, nausea, fever, and icterus of the skin and mucous membranes. He noticed that his urine had appeared dark for the past several days. The physician orders a series of biochemical tests. Based on the following test results, what is the most likely diagnosis?

• ALP: slightly elevated
• ALT: markedly elevated
• AST: markedly elevated
• GGT: slightly elevated
• Serum total bilirubin: moderately elevated
• Urine bilirubin: positive
• Fecal urobilinogen: decreased

Given the following results:

• ALP: slight increased
• AST: slight increased
• ALT: slight increased
• GGT: slight increased This is most consistent with:

Which of the following is both hormone and enzyme?

LOW LEVELS of maternal AFP indicate an increased risk for:

Which set of results is consistent with uncompensated metabolic acidosis?

Decreased T3 and T4, increased TSH:

Hirsutism, which can be quantified using a measurement technique known as the:

Which of the following is the most potent androgen?

PLUMBISM, a deleterious effect of gradual accumulation of ___ in body tissues, as a result of repeated exposure.

The half-life of the circulating cocaine is:

How should a laboratory verify the reference range it uses for a particular test?

A new reference interval is ESTABLISHED when there is no existing analyte or methodology in the clinical or reference laboratory with which to conduct comparative studies. It is a costly and labor-intensive study that will involve laboratory resources at all levels and may require from ___ to as many as 700 study individuals.

VERIFYING A REFERENCE INTERVAL (TRANSFERENCE): This is done to confirm the validity of an existing reference interval for an analyte using the same (identical) type of analytic system (method and/or instrument). These are the most common reference interval studies performed in the clinical laboratory and can require as few as ___ study individuals.