Vomiting Zones and Mechanism Quiz
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Questions and Answers

What does the CTZ respond directly to?

  • Auditory stimuli
  • Tactile stimuli
  • Visual stimuli
  • Chemical stimuli in the blood or cerebrospinal fluid (correct)
  • What does the vomiting center coordinate?

  • Taste perception
  • Auditory perception
  • Visual perception
  • Motor mechanism of vomiting (correct)
  • Which factors are trigger factors for vomiting?

  • Hormonal imbalance, Allergic reactions
  • Genetic factors, Nutritional imbalance
  • Physical disease, Environmental factors
  • Metabolic disease, Psychological disease (correct)
  • What percentage of patients experience nausea and vomiting in anticipation of chemotherapy?

    <p>10 - 40%</p> Signup and view all the answers

    Which group is more susceptible to anticipation of chemotherapy-induced nausea and vomiting?

    <p>Women, Young patients</p> Signup and view all the answers

    Chemotherapy-induced nausea and vomiting (CINV) not only affect quality of life but can also lead to rejection of potentially curative chemotherapy.

    <p>True</p> Signup and view all the answers

    Uncontrolled vomiting can produce what?

    <p>Dehydration, Nutritional depletion</p> Signup and view all the answers

    What is the emetic potential of anticancer agents effective against?

    <p>Low or moderately emetogenic chemotherapeutic agents</p> Signup and view all the answers

    What are the side effects of Prochlorperazine?

    <p>Sedation, Liver dysfunction, Dystonias</p> Signup and view all the answers

    What does the vomiting center inhibit?

    <p>Salivation center</p> Signup and view all the answers

    Which class of drugs is important in treating emesis linked with chemotherapy due to their longer duration of action and superior efficacy?

    <p>Corticosteroids</p> Signup and view all the answers

    Which drug is indicated only for the treatment of chemotherapy-induced nausea and vomiting (CINV)?

    <p>Aprepitant</p> Signup and view all the answers

    Which drug undergoes extensive metabolism and may affect the metabolism of other drugs that are metabolized by CYP3A4?

    <p>Nabilone</p> Signup and view all the answers

    Which drug is appropriate for the treatment of simple nausea and vomiting, especially motion sickness?

    <p>Scopolamine</p> Signup and view all the answers

    Which drug class is useful in treating anticipatory vomiting due to their sedative, anxiolytic, and amnesic properties?

    <p>Benzodiazepines</p> Signup and view all the answers

    Which drug is indicated for severe chemotherapy-induced nausea and vomiting when other agents have failed in therapy?

    <p>Dronabinol</p> Signup and view all the answers

    Which drug is an antagonist of the Substance P/neurokinin-1 receptor?

    <p>Aprepitant</p> Signup and view all the answers

    Which drug class is effective against mildly to moderately emetogenic chemotherapy and involves blockade of prostaglandins?

    <p>Corticosteroids</p> Signup and view all the answers

    Which drug is used orally with dexamethasone and a 5-HT3 antagonist for severe chemotherapy-induced nausea?

    <p>Dronabinol</p> Signup and view all the answers

    Which drug class is indicated for highly or moderately emetogenic chemotherapy regimens?

    <p>Cannabinoids</p> Signup and view all the answers

    Which drug may cause hyperglycemia and is indicated for mild symptoms of nausea and vomiting?

    <p>Dronabinol</p> Signup and view all the answers

    Which drug class possesses anterograde amnesic properties and is useful in treating anticipatory vomiting?

    <p>Benzodiazepines</p> Signup and view all the answers

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