Podcast
Questions and Answers
What is the primary function of the inactivation gate peptide in sodium channels?
What is the primary function of the inactivation gate peptide in sodium channels?
- To restore inactivation and block open sodium channels (correct)
- To increase the refractory period of the neuron
- To decrease the voltage-sensor movement
- To activate the sodium channel
What is the result of the movement of the voltage-sensor in Domain IV of sodium channels?
What is the result of the movement of the voltage-sensor in Domain IV of sodium channels?
- Slow inactivation of the sodium channel
- Decreased refractory period of the neuron
- Activation of the sodium channel
- Fast inactivation of the sodium channel (correct)
What is the role of hydrophobic amino acid residues in sodium channels?
What is the role of hydrophobic amino acid residues in sodium channels?
- To increase the voltage-sensor movement
- To form a cluster required for fast Na+ channel inactivation (correct)
- To activate the sodium channel
- To decrease the refractory period of the neuron
What is the consequence of the refractory period on the neural code?
What is the consequence of the refractory period on the neural code?
What is the clinical significance of measuring the refractory period in peripheral nerve?
What is the clinical significance of measuring the refractory period in peripheral nerve?
What is the result of axonal myelination on the action potential refractory period?
What is the result of axonal myelination on the action potential refractory period?
What happens to the sodium ions during the repolarization of the membrane?
What happens to the sodium ions during the repolarization of the membrane?
What is the effect of the potassium ions leaving the cell during repolarization?
What is the effect of the potassium ions leaving the cell during repolarization?
What happens to the sodium channel's activation gate during repolarization?
What happens to the sodium channel's activation gate during repolarization?
What triggers the closure of the sodium channel's activation gate during repolarization?
What triggers the closure of the sodium channel's activation gate during repolarization?
What is the state of the sodium channel when its activation gate is closed and its inactivation gate is open?
What is the state of the sodium channel when its activation gate is closed and its inactivation gate is open?
Why do not all sodium channels inactivate during the action potential?
Why do not all sodium channels inactivate during the action potential?
What is the primary mechanism underlying the transmission of information in neurons?
What is the primary mechanism underlying the transmission of information in neurons?
What is the function of the activation gate in voltage-gated Na+ channels?
What is the function of the activation gate in voltage-gated Na+ channels?
What is the role of the inactivation gate in voltage-gated Na+ channels?
What is the role of the inactivation gate in voltage-gated Na+ channels?
What is the structural feature of voltage-gated K+ channels that differs from Na+ channels?
What is the structural feature of voltage-gated K+ channels that differs from Na+ channels?
What is the final state of a voltage-gated Na+ channel after activation?
What is the final state of a voltage-gated Na+ channel after activation?
What is the significance of the region between domains III and IV in voltage-gated Na+ channels?
What is the significance of the region between domains III and IV in voltage-gated Na+ channels?
