Vitamin D3 Metabolism and Function
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Questions and Answers

What is the active form of vitamin D that increases calcium absorption in the intestine?

  • 25-hydroxycholecalciferol
  • Cholecalciferol
  • 1,25-dihydroxycholecalciferol (correct)
  • Calcitonin
  • What hormone is primarily responsible for increasing the concentration of calcium in the blood?

  • Calcitonin
  • Insulin
  • Thyroid stimulating hormone (TSH)
  • Parathyroid hormone (PTH) (correct)
  • Which organ converts vitamin D3 into 25-hydroxycholecalciferol?

  • Liver (correct)
  • Thyroid gland
  • Skin
  • Kidney
  • What triggers the secretion of calcitonin?

    <p>Increase in calcium levels</p> Signup and view all the answers

    How does calcitonin affect the actions of parathyroid hormone (PTH)?

    <p>It inhibits PTH's actions</p> Signup and view all the answers

    Study Notes

    Vitamin D3 Metabolism

    • Vitamin D3 (cholecalciferol) is obtained through diet or sun exposure.
    • The liver converts vitamin D3 to 25-hydroxycholecalciferol (25-OH-D3), an inactive form.
    • The kidney hydroxylates 25-OH-D3 to 1,25-dihydroxycholecalciferol (1,25-[OH]2-D3), the active form.

    Vitamin D3 Function

    • The active form of vitamin D increases calcium (Ca2+) absorption in the intestines.
    • It enhances the effects of parathyroid hormone (PTH) on bone resorption.

    Calcitonin

    • Calcitonin is secreted by medullary cells in the thyroid gland.
    • Its secretion is triggered by elevated blood calcium (Ca2+) levels.
    • Calcitonin lowers blood calcium by inhibiting PTH and vitamin D.
    • Calcitonin is not typically secreted during normal calcium regulation.

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    Description

    This quiz explores the metabolism and physiological functions of vitamin D3, including its conversion processes in the liver and kidneys. It also covers the role of calcitonin in calcium regulation and its interactions with parathyroid hormone. Test your knowledge on these essential topics for understanding calcium homeostasis!

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