Biochem L1C | Lipid Soluble Vitamins
40 Questions
2 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the general cause of deficiency for lipid-soluble vitamins?

  • Inadequate intake/malnutrition (correct)
  • Complication of GI surgery
  • Poor absorption from the intestinal tract
  • Increased demand such as pregnancy
  • Which of the following vitamins act as hormones?

  • Vitamin D and E
  • Vitamin A and D (correct)
  • Vitamin E and K
  • Vitamin A and K
  • Which lipid-soluble vitamin is not readily absorbed from the diet?

  • Vitamin A
  • Vitamin K
  • Vitamin E
  • Vitamin D (correct)
  • What are the shared characteristics of lipid-soluble vitamins?

    <p>Stored in tissues and circulating concentrations kept constant</p> Signup and view all the answers

    Which vitamin can be toxic in excess, according to recent evidence?

    <p>Vitamin A</p> Signup and view all the answers

    When may deficiency of lipid-soluble vitamins develop?

    <p>All of the above</p> Signup and view all the answers

    Which of the following is a risk factor for developing hemorrhagic disease of the newborn due to vitamin K deficiency?

    <p>Premature birth</p> Signup and view all the answers

    Which vitamin is required for the post-translational modification of coagulation factors II, VII, IX, and X?

    <p>Vitamin K</p> Signup and view all the answers

    What can cause deficiency of vitamin K in humans?

    <p>Liver disease</p> Signup and view all the answers

    Which condition may result from vitamin E deficiency in premature infants?

    <p>Hemolytic anemia</p> Signup and view all the answers

    Which factor contains carboxylated residues requiring vitamin K for their activation?

    <p>Factor II (Prothrombin)</p> Signup and view all the answers

    What is the primary function of vitamin E?

    <p>Protects cell membranes</p> Signup and view all the answers

    What condition is associated with deficiency of vitamin K in newborn infants?

    <p>Hemorrhagic disease of the newborn</p> Signup and view all the answers

    What group of drugs inhibits the action of vitamin K?

    <p>(WARFARIN) Dicoumarin group</p> Signup and view all the answers

    What is the main source of vitamin K for newborn infants?

    <p>Intestinal microflora</p> Signup and view all the answers

    What condition may develop in premature infants due to vitamin E deficiency?

    <p>Hemolytic anemia</p> Signup and view all the answers

    Which vitamin is required for the carboxylation of specific glutamic acid residues in coagulation factors?

    <p>Vitamin K</p> Signup and view all the answers

    What may cause hemorrhagic disease of the newborn due to vitamin K deficiency?

    <p>Inefficient placental transfer of vitamin K</p> Signup and view all the answers

    Which of the following is true about the transport of calcitriol in plasma?

    <p>It is transported in plasma bound to vitamin D binding protein (DBP)</p> Signup and view all the answers

    What is the primary stimulus for the synthesis of 1,25(OH)2D3 from 25(OH)D3?

    <p>Parathyroid hormone (PTH)</p> Signup and view all the answers

    What is the function of calcitriol in the intestinal epithelium?

    <p>It induces gene expression in the nucleus</p> Signup and view all the answers

    What is a common outcome of vitamin D deficiency during pregnancy and infancy?

    <p>Development of rickets in children and osteomalacia in adults</p> Signup and view all the answers

    What are the adverse health outcomes linked to low vitamin D levels during pregnancy and infancy?

    <p>Increased incidence of autoimmune diseases</p> Signup and view all the answers

    What is the most likely cause of the 28-year-old woman's symptoms based on the given information?

    <p>Malabsorption syndrome</p> Signup and view all the answers

    What is the primary source of α-tocopherol?

    <p>Green leafy vegetables</p> Signup and view all the answers

    Which lipid-containing structures are associated with α-tocopherol due to its lipid solubility?

    <p>Membranes, lipoproteins, and fat deposits</p> Signup and view all the answers

    What is the main function of α-Tocopherol?

    <p>Inhibit the activity of protein kinase C</p> Signup and view all the answers

    Which statement about vitamin D toxicity is correct based on the given information?

    <p>Deposition of Ca2+ in soft tissue is a common outcome</p> Signup and view all the answers

    Which of the following is the most likely cause of night blindness and dry, scaly skin in a 32-year-old woman with decreased serum levels of retinol?

    <p>Impaired absorption of fat-soluble vitamins</p> Signup and view all the answers

    What is the storage form of vitamin D found in the liver and in the circulation?

    <p>Calcidiol</p> Signup and view all the answers

    Which form of vitamin D is synthesized in the skin by UV irradiation of 7-dehydrocholesterol?

    <p>Cholecalciferol</p> Signup and view all the answers

    What can cause vitamin D deficiency by disturbing enterohepatic circulation?

    <p>Impaired hepatic hydroxylation of vitamin D</p> Signup and view all the answers

    Which vitamin is a plant pigment that serves as a pro-vitamin for vitamin A?

    <p>Beta-carotene</p> Signup and view all the answers

    In which organ is retinol esterified and stored in the form of retinyl esters, bound to the cytosolic retinol-binding proteins?

    <p>Liver</p> Signup and view all the answers

    Which hydroxylase forms calcitriol (1α,25dihydroxycholecalciferol; 1,25[OH]2D3) from calcidiol (25hydroxycholecalciferol; 25[OH]D3) in the renal tubules?

    <p>CYP27B1</p> Signup and view all the answers

    What is the most common symptom of retinoid deficiency in children and pregnant women?

    <p>Night blindness</p> Signup and view all the answers

    Which receptor interacts with all-trans and 9-cis-retinoic acid?

    <p>RAR (retinoid acid receptors)</p> Signup and view all the answers

    What does retinoic acid interact with to regulate growth, differentiation, and proliferation of cells during embryonic development and organogenesis?

    <p>RAR (retinoid acid receptors)</p> Signup and view all the answers

    What health condition may result from excessive intake of retinoid?

    <p>Increased intracranial pressure</p> Signup and view all the answers

    What is the precursor and storage form of retinol found in animals?

    <p>Retinyl palmitate</p> Signup and view all the answers

    More Like This

    Vitamins 1
    38 questions

    Vitamins 1

    EntertainingLapSteelGuitar avatar
    EntertainingLapSteelGuitar
    Use Quizgecko on...
    Browser
    Browser