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Questions and Answers
Which coenzyme is required for the conversion of pyruvate to oxaloacetate?
Where does substrate level phosphorylation take place in glycolysis?
Where is ATP synthase located in the mitochondrion?
What drives ATP synthesis by ATP synthase?
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Which coenzyme is NOT involved in the reaction catalyzed by pyruvate dehydrogenase?
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Study Notes
Coenzymes and Pyruvate Conversion
- Conversion of pyruvate to oxaloacetate requires biotin as a coenzyme, which serves as a carrier of activated carbon dioxide.
Substrate Level Phosphorylation in Glycolysis
- Substrate-level phosphorylation occurs during glycolysis primarily during the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate and the conversion of phosphoenolpyruvate to pyruvate, generating ATP directly.
Location of ATP Synthase
- ATP synthase is located in the inner mitochondrial membrane, where it facilitates ATP production through oxidative phosphorylation.
Driving Force for ATP Synthesis
- ATP synthesis by ATP synthase is driven by a proton gradient established across the inner mitochondrial membrane, promoting the flow of protons back into the mitochondrial matrix.
Coenzyme NOT Involved in Pyruvate Dehydrogenase Reaction
- Coenzyme A is actively involved in the reaction catalyzed by pyruvate dehydrogenase, while NAD+ and FAD are also involved; however, coenzyme B is not involved in this specific reaction.
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Description
Test your knowledge of vitamin coenzymes and their involvement in enzyme actions with this quiz. Questions cover topics such as the specific coenzymes required for various metabolic conversions and the effects of inhibitors on enzyme activity.
