Virus Properties
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Virus Properties

Created by
@PerfectParadox

Questions and Answers

Which of the following agents is NOT typically used to inactivate viruses?

Ethanol

What is the primary reason why enveloped viruses are sensitive to ether?

The ether disrupts the viral lipid envelope

At what temperature can most viruses be stored for long-term preservation?

–40°C

What is the mechanism by which UV rays inactivate viruses?

<p>UV rays cause mutations in the viral genome</p> Signup and view all the answers

Which of the following statements about viruses is TRUE?

<p>Viruses are stable at low temperatures</p> Signup and view all the answers

What is a key advantage of using viral vectors for therapy?

<p>They can be readily amplified by replication in appropriate cells</p> Signup and view all the answers

Which of the following viruses is being developed as a vector for gene therapy?

<p>Vaccinia virus</p> Signup and view all the answers

What is the primary function of a viral vector in vaccine development?

<p>To carry and express genes as vaccines</p> Signup and view all the answers

What is an example of a gene that has been used in a viral vector-based vaccine?

<p>A gene coding the spike protein of SARS-CoV2</p> Signup and view all the answers

What is a benefit of using viral vectors to target specific tissues?

<p>They can deliver genes to specific tissues, reducing systemic side effects</p> Signup and view all the answers

Study Notes

Viral Sensitivity

  • Viruses are sensitive to UV rays
  • Viruses are sensitive to oxidizing agents, including:
    • Formaldehyde
    • Chlorine
    • Iodine
    • Hydrogen peroxide
  • Enveloped viruses are sensitive to ether

Viral Stability

  • Viruses are stable at low temperatures
  • Most viruses can be stored at -40°C
  • Viruses are preferably stored at -70°C

Viral Vectors for Therapy

  • Viral vectors can be easily amplified by replication in suitable cells
  • They allow for targeted delivery of DNA or RNA into specific tissues and cells

Viral Vectors in Development

  • Adenoviruses are being developed as vectors
  • Vaccinia virus is being developed as a vector
  • Vesicular stomatitis virus is being developed as a vector

Viral Vectors as Vaccines

  • Some viruses are being used to carry and express genes as vaccines
  • Adenovirus carrying the spike protein gene of SARS-CoV2 is being used as a vaccine

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Description

Learn about the sensitivity and stability of viruses, including their reactions to UV rays, oxidizing agents, and temperature.

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