Podcast
Questions and Answers
Which of the following agents is NOT typically used to inactivate viruses?
Which of the following agents is NOT typically used to inactivate viruses?
What is the primary reason why enveloped viruses are sensitive to ether?
What is the primary reason why enveloped viruses are sensitive to ether?
At what temperature can most viruses be stored for long-term preservation?
At what temperature can most viruses be stored for long-term preservation?
What is the mechanism by which UV rays inactivate viruses?
What is the mechanism by which UV rays inactivate viruses?
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Which of the following statements about viruses is TRUE?
Which of the following statements about viruses is TRUE?
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What is a key advantage of using viral vectors for therapy?
What is a key advantage of using viral vectors for therapy?
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Which of the following viruses is being developed as a vector for gene therapy?
Which of the following viruses is being developed as a vector for gene therapy?
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What is the primary function of a viral vector in vaccine development?
What is the primary function of a viral vector in vaccine development?
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What is an example of a gene that has been used in a viral vector-based vaccine?
What is an example of a gene that has been used in a viral vector-based vaccine?
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What is a benefit of using viral vectors to target specific tissues?
What is a benefit of using viral vectors to target specific tissues?
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Study Notes
Viral Sensitivity
- Viruses are sensitive to UV rays
- Viruses are sensitive to oxidizing agents, including:
- Formaldehyde
- Chlorine
- Iodine
- Hydrogen peroxide
- Enveloped viruses are sensitive to ether
Viral Stability
- Viruses are stable at low temperatures
- Most viruses can be stored at -40°C
- Viruses are preferably stored at -70°C
Viral Vectors for Therapy
- Viral vectors can be easily amplified by replication in suitable cells
- They allow for targeted delivery of DNA or RNA into specific tissues and cells
Viral Vectors in Development
- Adenoviruses are being developed as vectors
- Vaccinia virus is being developed as a vector
- Vesicular stomatitis virus is being developed as a vector
Viral Vectors as Vaccines
- Some viruses are being used to carry and express genes as vaccines
- Adenovirus carrying the spike protein gene of SARS-CoV2 is being used as a vaccine
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Description
Learn about the sensitivity and stability of viruses, including their reactions to UV rays, oxidizing agents, and temperature.
