Virus Infection Quiz
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Questions and Answers

What characteristic of viruses contributes to their classification as non-living pathogens?

  • They are acellular (correct)
  • Their unique type of cells
  • Their ability to synthesize only some of their own components
  • Their extremely small size

How do viruses compare to both prokaryotic and eukaryotic cells?

  • They have similar metabolic processes
  • They lack genetic material
  • They lack proteins
  • They are generally smaller (correct)

In the scenario described, what type of infectious agent is indicated by the presence of RNA and protein but no carbohydrates or lipids?

  • Bacteria
  • Fungi
  • Viroids
  • Prions (correct)

What happens when a virus has an envelope?

<p>It likely escapes its host cell by budding. (D)</p> Signup and view all the answers

In the given pictures, which one shows an icosahedral enveloped virus with spikes?

<p>C (A)</p> Signup and view all the answers

What must all viruses do with their genome to produce ____, used by the host cell to produce ____?

<p>mRNA; proteins (B)</p> Signup and view all the answers

What do retroviruses use reverse transcriptase for?

<p>Direct the production of double-stranded DNA from a single-stranded RNA genome (C)</p> Signup and view all the answers

If a newly-discovered double-stranded RNA virus has a unique enzyme synthesizing double-stranded RNA using an RNA template, what is likely true?

<p>The virus must bring this enzyme into the host cell as animal cells do not have this capability. (C)</p> Signup and view all the answers

What contributes to viral genome evolution?

<p>All of the above (D)</p> Signup and view all the answers

Which property is currently not used to classify viruses?

<p>Host range of the virus (E)</p> Signup and view all the answers

Which event occurs during lysogenic replication of bacteriophage but not during lytic replication?

<p>Integration of the phage DNA into the host cell DNA (B)</p> Signup and view all the answers

Which process during lytic replication of bacteriophage uses factors from the host cell?

<p>Enzymes which transcribe and translate viral genes (E)</p> Signup and view all the answers

What is a characteristic of viruses that infect many different tissue types?

<p>Broad tropism (D)</p> Signup and view all the answers

Which suffix denotes the 'family' level of classification for viruses?

<p>-viridae (E)</p> Signup and view all the answers

In influenza virus, antigenic drift is characterized by what type of change in HA or NA spikes?

<p>Spontaneous mutation leading to a minor change (C)</p> Signup and view all the answers

Which description does not match antigenic shift in the influenza virus?

<p>Often results from spontaneous mutations (C)</p> Signup and view all the answers

Which viral family and its associated disease contains single-stranded+ RNA and reverse transcriptase?

<p>Retroviridae (AIDS) (E)</p> Signup and view all the answers

All these are DNA viruses except which one?

<p>Picornaviridae (D)</p> Signup and view all the answers

Which prion disease can be acquired by eating beef contaminated with a cattle prion?

<p>Gerstmann-Straussler-Schienker syndrome (A)</p> Signup and view all the answers

How would the SARS-CoV2 virion structure be best described?

<p>Naked icosahedral (B)</p> Signup and view all the answers

Which viral family contains single-stranded, positive-sense, nonsegmented RNA?

<p>Filoviridae (Ebola) (B)</p> Signup and view all the answers

What is the human receptor protein for the SARS-CoV2 virus?

<p>ACE-1 (D)</p> Signup and view all the answers

What type of viral infection is indicated by a patient presenting with fever, sore throat, and lesions that resolve but recur two months later?

<p>Chronic persistent infection (A)</p> Signup and view all the answers

How do convalescent antibodies help treat patients with serious COVID-19 cases?

<p>Have a placebo effect. (B)</p> Signup and view all the answers

Both viruses and prokaryotes reproduce by:

<p>Budding (D)</p> Signup and view all the answers

Which term refers to the number of species that a specific virus can infect?

<p>Host range (B)</p> Signup and view all the answers

In viral infections, what is the role of tropism?

<p>Attachment to host cells (A)</p> Signup and view all the answers

How do naked viruses typically exit animal host cells?

<p>By budding (A)</p> Signup and view all the answers

What occurs in persistent viral infections?

<p>Viral integration into host cell DNA (B)</p> Signup and view all the answers

What is the primary difference between lytic and lysogenic bacteriophage replication?

<p>Viral genome replication method (B)</p> Signup and view all the answers

Which procedure is used to detect both viral antigens and patient antibodies to a virus?

<p>ELISA (A)</p> Signup and view all the answers

What do antiviral drugs primarily target in viral replication?

<p>Viral nucleic acid production (B)</p> Signup and view all the answers

Why do new influenza vaccines need to be formulated annually?

<p>To prevent antigenic drift (A)</p> Signup and view all the answers

What term describes major genetic reassortment in influenza viruses?

<p>Provirus formation (D)</p> Signup and view all the answers

Which stage in viral infection involves the entrance of only the genome into a host cell?

<p>Penetration (B)</p> Signup and view all the answers

What is the probable explanation when a plate is completely clear after incubation with a liquid suspension of bacteriophage and host bacteria?

<p>The phage concentration was so high that all the host bacterial cells were killed. (A)</p> Signup and view all the answers

What does the plaque assay primarily determine?

<p>Number of bacteriophage in a sample (C)</p> Signup and view all the answers

Which test works by detecting viral nucleic acid?

<p>PCR (D)</p> Signup and view all the answers

What should be considered about using an agglutination test for HIV antibodies one week after a high-risk behavior?

<p>One week may not be enough time for HIV antibodies to be detected. (B)</p> Signup and view all the answers

What is a major challenge in developing effective antiviral drugs with minimal side effects?

<p>Viruses use the cell's own machinery and metabolism for replication. (A)</p> Signup and view all the answers

Prions are:

<p>Misfolded proteins which can cause normal versions to also misfold. (B)</p> Signup and view all the answers

What is likely when a plate remains clear after incubation with a bacteriophage and host bacteria?

<p>The bacteria are resistant to the bacteriophage. (D)</p> Signup and view all the answers

What is a key challenge in developing antiviral drugs?

<p>Viruses mutate rapidly and can develop resistance to drugs. (C)</p> Signup and view all the answers

What is a limitation of using agglutination tests for viral infections?

<p>They cannot differentiate between different strains of the same virus. (D)</p> Signup and view all the answers

What characterizes prions?

<p>They misfold normal cellular proteins, leading to disease. (A)</p> Signup and view all the answers

What stage of animal virus replication may be blocked by a drug that binds with the viral spike?

<p>Attachment (A)</p> Signup and view all the answers

Which part of viral replication is being blocked by the lack of a receptor in individuals with a genetic mutation?

<p>HIV cannot attach to the host cell without the proper membrane receptor. (D)</p> Signup and view all the answers

What type of viral infection is demonstrated by a graph showing periods of active replication alternating with periods of dormancy?

<p>Chronic persistent (B)</p> Signup and view all the answers

Which statement is not true about chronic persistent viral infections?

<p>May involve integration of the virus into host cell DNA. (B)</p> Signup and view all the answers

What stage of viral replication involves penetration via endocytosis?

<p>Penetration via membrane fusion (A)</p> Signup and view all the answers

In which stage of animal virus replication will not be different between naked and enveloped viruses?

<p>Replication (B)</p> Signup and view all the answers

Which is not true about oncogenic viruses?

<p>They are never RNA viruses. (B)</p> Signup and view all the answers

Which cancer type is not linked to a specific virus?

<p>Skin cancer (C)</p> Signup and view all the answers

During a lysogenic infection, what happens to the phage DNA?

<p>It remains as a prophage and is copied whenever the host cell replicates its genome (A)</p> Signup and view all the answers

What enzyme breaks down the host cell wall to release the bacteriophage?

<p>Lysozyme (D)</p> Signup and view all the answers

How can an antiviral drug target the uncoating step of viral replication?

<p>By preventing access to the virus nucleic acid (A)</p> Signup and view all the answers

Which drug family targets replication by preventing viral nucleic acids from being replicated or transcribed?

<p>Nucleoside reverse transcriptase inhibitors (AZT) (D)</p> Signup and view all the answers

What is one characteristic shared by prions and misfolded proteins in neurodegenerative disorders?

<p>They are infectious (A)</p> Signup and view all the answers

How does a prophage pass down to bacterium's daughter cells?

<p>Through binary fission (C)</p> Signup and view all the answers

Which step of viral replication involves preventing mature virions from being put together?

<p>Assembly (D)</p> Signup and view all the answers

Why are Alzheimer's, Parkinson's, and ALS considered 'prion-like' diseases according to recent medical research?

<p>Because misfolded proteins can transmit dysfunction similar to prions (B)</p> Signup and view all the answers

What is the role of enfuviritide in combating viral replication?

<p>Preventing attachment of the virus to the host cell receptor (A)</p> Signup and view all the answers

What is a mechanism shared between nucleoside reverse transcriptase inhibitors and ribavirin in targeting viral replication?

<p>Preventing access to virus nucleic acid for replication (C)</p> Signup and view all the answers

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