10 Questions
What controls which cell type a virus can infect?
The presence of the appropriate receptor on the cell surface
How do viruses enter the body?
By inhalation, ingestion, sexual intercourse, or inoculation through the skin or mucous membranes
How does a disseminated infection occur?
The virus replicates initially at the site of entry and then spreads throughout the body
What does the term 'incubation period' define?
The time from exposure to an organism to the onset of clinical disease
How do viruses cause infection in the central nervous system?
They replicate locally initially, then enter nerve endings and travel up the axon to infect the central nervous system.
How do viruses gain entry into the body?
Inhalation, ingestion, sexual intercourse, or inoculation through the skin or mucous membranes
What is the major factor that controls which cell type a virus can infect?
Presence of the appropriate receptor on the cell surface
How does a disseminated infection occur?
Virus replicates initially at the site of entry, then enters the blood or lymphatics and spreads throughout the body
Which route of transmission may lead to vertical transmission of infection from a mother to her foetus?
Transplacental transmission
What defines the time from exposure to an organism to the onset of clinical disease?
Incubation period
Study Notes
Virus Infection and Transmission
- The major factor that controls which cell type a virus can infect is the presence of specific receptors on the surface of the host cell.
- Viruses enter the body through various routes, including respiratory, gastrointestinal, and skin/mucous membrane portals.
- A disseminated infection occurs when a virus spreads through the bloodstream or lymphatic system, allowing it to infect multiple cells and organs.
- The incubation period defines the time from exposure to an organism to the onset of clinical disease, during which the virus multiplies and causes infection.
- Viruses can cause infection in the central nervous system by crossing the blood-brain barrier or through direct neural transmission.
- Viruses gain entry into the body through various means, including respiratory droplets, contaminated food and water, and vector transmission (e.g., mosquito bites).
- The vertical transmission of infection from a mother to her fetus can occur through the placenta, particularly during pregnancy, if the mother is infected with a virus.
- The incubation period is the time between exposure to a virus and the onset of symptoms, during which the virus replicates and causes disease.
Explore the mechanisms of virus infection and cell tropism, including the factors influencing which cell types a virus can infect and the methods through which viruses enter the body. Learn about the role of receptors in virus entry and the various modes of viral transmission.
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