Virus Classification and Genome Composition Quiz

Prions can cross species boundaries

Transmission & spread requires exposure to the infective agent by

Prion diseases are difficult to diagnose

Prevention & treatment of prion diseases

Prions lack a nucleic acid genome

Prions arise by mutation then hijack protein-folding control

Virus classification is based on the mechanism of mRNA production, known as the _____________ classification.

During viral replication, the viral genome is copied through a process called _____________.

Viral particles are released from the host cell through cell lysis or _____________.

Viruses can be transmitted through respiratory droplets, aerosols, or by the _____________ route.

Vaccination is the best medical method to prevent infection and disease caused by _____________.

Hepatitis B and C viruses are known to cause _____________ cancer.

PCR stands for Polymerase Chain ______

Real-time PCR is used to ______ the recent H7N9 viruses from other H7 viruses

Prions are infectious agents composed entirely of ______ material

Prions are associated with degenerative changes in the ______, with large vacuoles in the CNS

Prions are resistant to heat, disinfectants, and ______

Variant CJD (vCJD) can produce symptoms much more ______ than other prion diseases

Viruses and prions are classified as ______

A virus is a small, infectious, obligate intracellular ______

The genome of a virus is composed of either ______ or ______, enclosed in a protein coat

The smallest 'virus' known to infect animals is the ______.

The largest RNA viral genome belongs to the ______.

The genome of SARS-CoV-2 encodes for more than ______ proteins.

A typical virus has a ______, ______, and ______.

Viruses are parasites; they depend on cells for molecular building blocks, machinery and _______.

Most viruses have dimensions that range from approximately 20 – 200 _______.

The genome size of a virus is measured in _______ base pairs.

Prions are resistant to heat, disinfectants, and _______.

The classification of viruses is based on the mechanism of _______ production.

Variant CJD (vCJD) can produce symptoms much more _______ than other prion diseases.

Coronaviruses belong to Group IV ((+)ssRNA) and the family _____________

The genome of Hepatitis B virus is approximately ______ kb in size

The smallest 'virus' known to infect animals is the ______ virus

A typical virus has a ______, ______, and ______.

Enveloped viruses take a lipid layer from the infected cell and usually ______ from it.

The genome of SARS-CoV-2 encodes for more than ______ proteins.

Viruses are classified based on their ________ production mechanism.

A typical virus has a ______, ______, and ______.

Enveloped viruses take a lipid layer from the infected cell and usually ______ from it.

Virus particles are released from the host cell through cell lysis or _________

The type of receptor a virus can attach to will define its host and tissue ________

During viral replication, the viral genome is copied through a process called _________

Viruses are parasites; they depend on cells for molecular building blocks, machinery and _______.

Coronaviruses belong to Group IV ((+)ssRNA) and the family _____________.

The genome of SARS-CoV-2 encodes for more than ______ proteins.

Prions are resistant to heat, disinfectants, and _______

Prions are associated with degenerative changes in the ______, with large vacuoles in the CNS

Prions can cross species boundaries and spread of scrapie agents between species have been transmitted to laboratory rodents and ______

Prions are infectious agents composed entirely of ______ material

Prions are host-derived molecules q PrPSc (prion protein scrapie) n a 30–35 kDa glycoprotein derived from PrPc n associated with intracellular fibrils in diseased tissue n can be found in the lymphoreticular system (tonsils, spleen & neurological tissues) n q may be carried in the blood by lymphocytes PrPc n a naturally occurring cellular prion protein n expressed predominantly on surface of nerve cells n coded by a single copy gene (on chromosome 20 in humans), with unknown function Prions are host-derived molecules q PrPSc & PrPc highly similar sequence differ in structure & protease resistance q PrPc Soluble, linear enzyme susceptible q PrPSc Insoluble globular enzyme resistant Soluble linear α-helices proteins (PrPc) à modified (misfolded) & accumulate as insoluble ß-sheet rich amyloid fibrils (PrPSc)

Prions lack a ______ acid genome

Viruses are parasites; they depend on cells for molecular building blocks, machinery and _______.

Enveloped viruses take a lipid layer from the infected cell and usually ______ from it.

The genome size of a virus is measured in _______ base pairs.

Prions are infectious agents composed entirely of ______ material

The genome of SARS-CoV-2 encodes for more than ______ proteins

Viruses are classified based on their ________ production mechanism

During viral replication, the viral genome is copied through a process called _________

A typical virus has a ______, ______, and ______.

Enveloped viruses take a lipid layer from the infected cell and usually ______ from it.

Prion diseases are caused by misfolded ______ proteins.

Variant CJD (vCJD) can produce symptoms much more ______ than other prion diseases.

Viral particles are released from the host cell through cell lysis or _________.

Prions are infectious agents composed entirely of ______ material

The genome size of a virus is measured in _______ base pairs

The type of receptor a virus can attach to will define its host and tissue ________