Virology Lecture 5: DNA Viruses and Asfarviridae Family

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What is the capsid symmetry of the Asfarviridae family?

Helical

Icosahedral (correct)

Cubic

Pleomorphic

Which of the following is a characteristic of the Poxviridae family?

Replicate in the nucleus

Have a helical capsid symmetry

Are sensitive to drying

Have a small genome size (correct)

What type of genome does the Asfarviridae family have?

dsDNA (correct)

ssDNA

dsRNA

ssRNA

What is the only known DNA arbovirus (arthropod-borne virus)?

African swine fever virus Signup and view all the answers

What is the difference between localized and systemic infection in the Poxviridae family?

Localized infection leads to localized skin lesions, while systemic infection leads to generalized skin lesions. Signup and view all the answers

How long can ASFV remain stable in chilled meat?

15 weeks Signup and view all the answers

How many genera are there in the Poxviridae family?

8 Signup and view all the answers

What type of nucleic acid does the Orf virus contain?

dsDNA Signup and view all the answers

Which of the following is NOT a property of the Herpesviridae virus family?

Helical capsid symmetry Signup and view all the answers

Which of the following subfamilies does the Orf virus belong to?

Alphaherpesvirinae Signup and view all the answers

Which virus causes infectious bovine rhinotracheitis in cattle?

Bovine herpesvirus 1 Signup and view all the answers

During a latent herpesvirus infection, where is the viral genome typically found?

In neurons (sensory or sympathetic) Signup and view all the answers

What type of nucleic acid does the Papillomaviridae family of viruses contain?

dsDNA Signup and view all the answers

Which of the following is NOT a property of the Papillomaviridae virus family?

Enveloped virions Signup and view all the answers

What type of lesions can the Papillomaviridae family of viruses cause?

All of the above Signup and view all the answers

Which of the following can trigger reactivation of a latent herpesvirus infection?

All of the above Signup and view all the answers

Which family of viruses is known for infecting basal keratinocytes and causing cells to continue dividing?

Papillomaviridae Signup and view all the answers

What are the proteins encoded by the E6 and E7 genes in Papillomaviridae viruses?

T antigens Signup and view all the answers

Which property is shared by members of the Parvoviridae family?

Non-enveloped viruses Signup and view all the answers

What is a common characteristic of Parvoviridae viruses?

They can only infect actively dividing cells Signup and view all the answers

Which statement about Papillomaviridae viruses is true?

They induce oncogenesis through their E6 and E7 proteins Signup and view all the answers

Which genus of the Parvoviridae family includes the Canine parvovirus 2 (CPV-2) and Feline panleukopenia virus (FPV)?

Protoparvovirus Signup and view all the answers

Which cells are typically infected by Canine parvovirus 2 (CPV-2) and Feline panleukopenia virus (FPV)?

Hemopoetic/stem cells in bone marrow and lymph organs Signup and view all the answers

What is a characteristic of Parvoviridae viruses that makes them difficult to eliminate from contaminated premises?

Their stability and resistance to disinfection Signup and view all the answers

Which statement about the Papillomaviridae virus life cycle is true?

They cause infected cells to lose their nucleus and detach from the basement membrane Signup and view all the answers

What is the capsid symmetry of the Poxviridae family?

Icosahedral Signup and view all the answers

What distinguishes the Asfarviridae family from the Poxviridae family in terms of virion size?

Asfarviridae virions are larger Signup and view all the answers

What makes African swine fever virus (ASFV) resistant to protease enzymes?

dsDNA genome Signup and view all the answers

What distinguishes Asfarviridae viruses from Papillomaviridae viruses in terms of transmission?

Asfarviridae are transmitted by arthropods Signup and view all the answers

What is the primary target of Papillomaviridae viruses in the human body?

Basal keratinocytes Signup and view all the answers

Which phase of the cell cycle do most DNA viruses, including Papillomaviridae, need cells to be in for replication?

S phase Signup and view all the answers

What is the role of T antigens, encoded by E6 and E7 genes, in the life cycle of Papillomaviridae viruses?

Promote host cell S phase entry Signup and view all the answers

Which type of cells are primarily targeted by Canine parvovirus 2 (CPV-2) and Feline panleukopenia virus (FPV) for infection?

Actively dividing cells in bone marrow Signup and view all the answers

Which family of viruses is known for causing cell transformation and the development of papillomas?