34 Questions
What is the capsid symmetry of the Asfarviridae family?
Icosahedral
Which of the following is a characteristic of the Poxviridae family?
Have a small genome size
What type of genome does the Asfarviridae family have?
dsDNA
What is the only known DNA arbovirus (arthropod-borne virus)?
African swine fever virus
What is the difference between localized and systemic infection in the Poxviridae family?
Localized infection leads to localized skin lesions, while systemic infection leads to generalized skin lesions.
How long can ASFV remain stable in chilled meat?
15 weeks
How many genera are there in the Poxviridae family?
8
What type of nucleic acid does the Orf virus contain?
dsDNA
Which of the following is NOT a property of the Herpesviridae virus family?
Helical capsid symmetry
Which of the following subfamilies does the Orf virus belong to?
Alphaherpesvirinae
Which virus causes infectious bovine rhinotracheitis in cattle?
Bovine herpesvirus 1
During a latent herpesvirus infection, where is the viral genome typically found?
In neurons (sensory or sympathetic)
What type of nucleic acid does the Papillomaviridae family of viruses contain?
dsDNA
Which of the following is NOT a property of the Papillomaviridae virus family?
Enveloped virions
What type of lesions can the Papillomaviridae family of viruses cause?
All of the above
Which of the following can trigger reactivation of a latent herpesvirus infection?
All of the above
Which family of viruses is known for infecting basal keratinocytes and causing cells to continue dividing?
Papillomaviridae
What are the proteins encoded by the E6 and E7 genes in Papillomaviridae viruses?
T antigens
Which property is shared by members of the Parvoviridae family?
Non-enveloped viruses
What is a common characteristic of Parvoviridae viruses?
They can only infect actively dividing cells
Which statement about Papillomaviridae viruses is true?
They induce oncogenesis through their E6 and E7 proteins
Which genus of the Parvoviridae family includes the Canine parvovirus 2 (CPV-2) and Feline panleukopenia virus (FPV)?
Protoparvovirus
Which cells are typically infected by Canine parvovirus 2 (CPV-2) and Feline panleukopenia virus (FPV)?
Hemopoetic/stem cells in bone marrow and lymph organs
What is a characteristic of Parvoviridae viruses that makes them difficult to eliminate from contaminated premises?
Their stability and resistance to disinfection
Which statement about the Papillomaviridae virus life cycle is true?
They cause infected cells to lose their nucleus and detach from the basement membrane
What is the capsid symmetry of the Poxviridae family?
Icosahedral
What distinguishes the Asfarviridae family from the Poxviridae family in terms of virion size?
Asfarviridae virions are larger
What makes African swine fever virus (ASFV) resistant to protease enzymes?
dsDNA genome
What distinguishes Asfarviridae viruses from Papillomaviridae viruses in terms of transmission?
Asfarviridae are transmitted by arthropods
What is the primary target of Papillomaviridae viruses in the human body?
Basal keratinocytes
Which phase of the cell cycle do most DNA viruses, including Papillomaviridae, need cells to be in for replication?
S phase
What is the role of T antigens, encoded by E6 and E7 genes, in the life cycle of Papillomaviridae viruses?
Promote host cell S phase entry
Which type of cells are primarily targeted by Canine parvovirus 2 (CPV-2) and Feline panleukopenia virus (FPV) for infection?
Actively dividing cells in bone marrow
Which family of viruses is known for causing cell transformation and the development of papillomas?
Papillomaviridae
Learn about DNA viruses, specifically focusing on the Asfarviridae family properties such as African swine fever virus. Explore topics like dsDNA structure, icosahedral capsid symmetry, and viral stability. Taught by Darryn Knobel BVSc MSc PhD.
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