Virology Lecture 5: DNA Viruses and Asfarviridae Family
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Questions and Answers

What is the capsid symmetry of the Asfarviridae family?

  • Helical
  • Icosahedral (correct)
  • Cubic
  • Pleomorphic

Which of the following is a characteristic of the Poxviridae family?

  • Replicate in the nucleus
  • Have a helical capsid symmetry
  • Are sensitive to drying
  • Have a small genome size (correct)

What type of genome does the Asfarviridae family have?

  • dsDNA (correct)
  • ssDNA
  • dsRNA
  • ssRNA

What is the only known DNA arbovirus (arthropod-borne virus)?

<p>African swine fever virus (D)</p> Signup and view all the answers

What is the difference between localized and systemic infection in the Poxviridae family?

<p>Localized infection leads to localized skin lesions, while systemic infection leads to generalized skin lesions. (C)</p> Signup and view all the answers

How long can ASFV remain stable in chilled meat?

<p>15 weeks (D)</p> Signup and view all the answers

How many genera are there in the Poxviridae family?

<p>8 (A)</p> Signup and view all the answers

What type of nucleic acid does the Orf virus contain?

<p>dsDNA (B)</p> Signup and view all the answers

Which of the following is NOT a property of the Herpesviridae virus family?

<p>Helical capsid symmetry (A)</p> Signup and view all the answers

Which of the following subfamilies does the Orf virus belong to?

<p>Alphaherpesvirinae (A)</p> Signup and view all the answers

Which virus causes infectious bovine rhinotracheitis in cattle?

<p>Bovine herpesvirus 1 (D)</p> Signup and view all the answers

During a latent herpesvirus infection, where is the viral genome typically found?

<p>In neurons (sensory or sympathetic) (C)</p> Signup and view all the answers

What type of nucleic acid does the Papillomaviridae family of viruses contain?

<p>dsDNA (B)</p> Signup and view all the answers

Which of the following is NOT a property of the Papillomaviridae virus family?

<p>Enveloped virions (B)</p> Signup and view all the answers

What type of lesions can the Papillomaviridae family of viruses cause?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following can trigger reactivation of a latent herpesvirus infection?

<p>All of the above (D)</p> Signup and view all the answers

Which family of viruses is known for infecting basal keratinocytes and causing cells to continue dividing?

<p>Papillomaviridae (A)</p> Signup and view all the answers

What are the proteins encoded by the E6 and E7 genes in Papillomaviridae viruses?

<p>T antigens (A)</p> Signup and view all the answers

Which property is shared by members of the Parvoviridae family?

<p>Non-enveloped viruses (C)</p> Signup and view all the answers

What is a common characteristic of Parvoviridae viruses?

<p>They can only infect actively dividing cells (D)</p> Signup and view all the answers

Which statement about Papillomaviridae viruses is true?

<p>They induce oncogenesis through their E6 and E7 proteins (A)</p> Signup and view all the answers

Which genus of the Parvoviridae family includes the Canine parvovirus 2 (CPV-2) and Feline panleukopenia virus (FPV)?

<p>Protoparvovirus (D)</p> Signup and view all the answers

Which cells are typically infected by Canine parvovirus 2 (CPV-2) and Feline panleukopenia virus (FPV)?

<p>Hemopoetic/stem cells in bone marrow and lymph organs (A)</p> Signup and view all the answers

What is a characteristic of Parvoviridae viruses that makes them difficult to eliminate from contaminated premises?

<p>Their stability and resistance to disinfection (B)</p> Signup and view all the answers

Which statement about the Papillomaviridae virus life cycle is true?

<p>They cause infected cells to lose their nucleus and detach from the basement membrane (B)</p> Signup and view all the answers

What is the capsid symmetry of the Poxviridae family?

<p>Icosahedral (B)</p> Signup and view all the answers

What distinguishes the Asfarviridae family from the Poxviridae family in terms of virion size?

<p>Asfarviridae virions are larger (A)</p> Signup and view all the answers

What makes African swine fever virus (ASFV) resistant to protease enzymes?

<p>dsDNA genome (A)</p> Signup and view all the answers

What distinguishes Asfarviridae viruses from Papillomaviridae viruses in terms of transmission?

<p>Asfarviridae are transmitted by arthropods (A)</p> Signup and view all the answers

What is the primary target of Papillomaviridae viruses in the human body?

<p>Basal keratinocytes (D)</p> Signup and view all the answers

Which phase of the cell cycle do most DNA viruses, including Papillomaviridae, need cells to be in for replication?

<p>S phase (A)</p> Signup and view all the answers

What is the role of T antigens, encoded by E6 and E7 genes, in the life cycle of Papillomaviridae viruses?

<p>Promote host cell S phase entry (B)</p> Signup and view all the answers

Which type of cells are primarily targeted by Canine parvovirus 2 (CPV-2) and Feline panleukopenia virus (FPV) for infection?

<p>Actively dividing cells in bone marrow (C)</p> Signup and view all the answers

Which family of viruses is known for causing cell transformation and the development of papillomas?

<p><strong>Papillomaviridae</strong> (C)</p> Signup and view all the answers

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