Virology Lecture 3: Orthomyxoviruses Introduction

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Questions and Answers

Which type of influenza viruses are responsible for seasonal flu epidemics?

  • Influenza C
  • Influenza B
  • Influenza D
  • Influenza A (correct)

What is the composition of the Orthomyxoviruses virion?

  • RNA (2%), protein (70%), lipid (15%), carbohydrate (13%)
  • RNA (5%), protein (80%), lipid (10%), carbohydrate (5%)
  • RNA (1%), protein (73%), lipid (20%), carbohydrate (6%) (correct)
  • RNA (10%), protein (60%), lipid (20%), carbohydrate (10%)

Which of the following types of Orthomyxoviruses infect humans?

  • Influenza A, B, C, and D
  • Influenza B, C, and D
  • Influenza A, C, and D
  • Influenza A, B, and C (correct)

What is the typical incubation period for human influenza?

<p>1 to 4 days (D)</p> Signup and view all the answers

What type of specimens are more sensitive than pharyngeal swabs for the laboratory diagnosis of human influenza?

<p>Nasal washes and nasopharyngeal aspirates (D)</p> Signup and view all the answers

Which of the following symptoms are commonly associated with uncomplicated infections of human influenza?

<p>Fever and chills (D)</p> Signup and view all the answers

Where does the replication of the genome in influenza viruses take place?

<p>Nucleus (A)</p> Signup and view all the answers

Which influenza virus protein has the ability to inhibit interferon mRNA?

<p>NS1 (B)</p> Signup and view all the answers

What does 'antigenic shift' in influenza virus refer to?

<p>Major change in genome (D)</p> Signup and view all the answers

All of the following are functions of Neuraminidase (NA) except:

<p>It assists in viral genome replication. (C)</p> Signup and view all the answers

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