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Questions and Answers
What role do some viruses play in agriculture?
What role do some viruses play in agriculture?
Which of the following is a reason for studying viruses that do not involve disease?
Which of the following is a reason for studying viruses that do not involve disease?
How have some modified strains of viruses contributed to cancer treatment?
How have some modified strains of viruses contributed to cancer treatment?
Why has interest in bacteriophages revived recently?
Why has interest in bacteriophages revived recently?
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What is a key characteristic of retroviruses that makes them useful in gene therapy?
What is a key characteristic of retroviruses that makes them useful in gene therapy?
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What is a key feature that differentiates viruses from other microorganisms?
What is a key feature that differentiates viruses from other microorganisms?
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How are viruses classified in terms of their structural components?
How are viruses classified in terms of their structural components?
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What aspect of virus infection demonstrates their specific targeting ability?
What aspect of virus infection demonstrates their specific targeting ability?
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What is true regarding the observation of viruses under a microscope?
What is true regarding the observation of viruses under a microscope?
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What is a limitation of studying viruses compared to other microorganisms?
What is a limitation of studying viruses compared to other microorganisms?
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Study Notes
Reasons for Studying Viruses
- Viruses are significant agents of human diseases, ranging from common colds to lethal infections like rabies.
- Understanding virus nature, replication, and disease causation is essential for effective treatment and prevention.
- Viruses also contribute to the development of various cancers, highlighting the need for in-depth study in virology.
- Veterinary virology is crucial due to the economic impact of viruses affecting domestic animals.
- Plant virology is important for the agricultural economy, as many crop diseases are caused by viruses.
Useful Applications of Viruses
- Certain viruses are studied for their beneficial applications in various fields.
- Enzymes from viruses, such as reverse transcriptases from retroviruses and RNA polymerases from bacteriophages, are valuable in molecular biology.
- Baculoviruses are used as biological pesticides to control insect pests effectively.
- Myxoma virus has been employed to manage rabbit populations, demonstrating a practical application of viruses in ecology.
- Bacteriophages were historically used to treat bacterial infections before the rise of antibiotics; interest in them has resurged due to antibiotic resistance.
- Genetically modified viruses, like herpes simplex and vaccinia viruses, are being explored as targeted anti-cancer agents that selectively destroy tumor cells while sparing normal cells.
- Retroviruses are being used as gene therapy vectors to correct genetic disorders, such as severe combined immunodeficiency, by delivering functional genes into patient stem cells.
Overview of Virology
- Virology is a subfield of microbiology focusing on the study of viruses.
Characteristics of Viruses
- Viruses are small, measuring between 10 to 400 nanometers; invisible under light microscopes but detectable with electron microscopes.
- Structure is simple, primarily composed of a nucleic acid genome encased in a protective protein shell; may include a lipoprotein envelope.
- Classified as obligate intracellular pathogens, meaning they can only reproduce within living host cells.
Virus Replication
- After invading a host cell, viruses hijack the cell's machinery to produce new virus particles, showcasing their ability to self-replicate.
- Highly host and cell-specific; viruses exhibit strict specificity, such that a plant virus cannot infect animals, and viruses targeting specific organs (e.g., lungs) do not infect others (e.g., liver).
Cultivation of Viruses
- Viruses cannot be grown on artificial media (in vitro) and must replicate within a living organism (in vivo) to propagate.
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Description
This quiz explores the critical reasons for studying viruses, including their role in human diseases and their economic impact in veterinary and plant virology. Understanding viruses is essential for addressing both health concerns and agricultural productivity. Test your knowledge on the diversity and significance of viruses.