Virology Basics: Introduction to Viruses
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Questions and Answers

What is the main function of the viral genome in directing the synthesis of viral components?

  • Replication of the viral genome
  • Formation of infectious progeny virions (correct)
  • Synthesis of cellular components
  • Cellular energy generation

What distinguishes viroids from viruses based on the provided text?

  • Viroids have a DNA genome
  • Viroids contain a biosynthetic system
  • Viroids lack a protein coat (correct)
  • Viroids infect bacteria

What is a prion?

  • DNA segment
  • Single-celled organism
  • Single protein molecule (correct)
  • RNA molecule

Which ancient text mentions evidence of several viral diseases?

<p>The Iliad by Homer (C)</p> Signup and view all the answers

What initiates the next infectious cycle in viruses?

<p>Progeny virion disassembly (D)</p> Signup and view all the answers

How long have viruses been known as distinct biological entities?

<p>Less than 100 years (A)</p> Signup and view all the answers

What did Beijerinck term the submicroscopic agent responsible for tobacco mosaic disease?

<p>Contagium vivum fluidum (D)</p> Signup and view all the answers

Who identified viruses that cause leukemias or solid tumors in chickens in 1908 and 1911, respectively?

<p>Vilhelm Ellerman and Olaf Bang (D)</p> Signup and view all the answers

Who first recognized that bacteria could be hosts to viruses?

<p>Friedrick Twort (B)</p> Signup and view all the answers

What is the function of capsid in a virus?

<p>Encloses the nucleic acid genome (B)</p> Signup and view all the answers

When was the term 'virus' eventually simplified from contagium vivum fluidum?

<p>1898 (C)</p> Signup and view all the answers

What did Loeffler and Frosch deduce about infectious filterable agents in 1898?

<p>Comprised small particles (B)</p> Signup and view all the answers

What was the practice called where healthy individuals were inoculated with material from smallpox pustules?

<p>Variolation (D)</p> Signup and view all the answers

What did variolation involve?

<p>Inoculating healthy individuals with smallpox material (B)</p> Signup and view all the answers

Who recognized the principle on which modern methods of viral immunization are based?

<p>Edward Jenner (B)</p> Signup and view all the answers

What observation led Edward Jenner to his great insight regarding smallpox protection?

<p>Milkmaids contracted cowpox (C)</p> Signup and view all the answers

What were the consequences of variolation according to the text?

<p>Serious skin lesions at the site of inoculation and rash (C)</p> Signup and view all the answers

What event occurred in the 11th century in China and India related to smallpox?

<p>Widespread practice of variolation (A)</p> Signup and view all the answers

What is a key difference between the nucleocapsids of viruses with helical symmetry and icosahedral structures?

<p>Regular, periodic interaction between capsid protein and nucleic acid (B)</p> Signup and view all the answers

Which type of genome is typically found in animal viruses with helical symmetry?

<p>RNA genomes (A)</p> Signup and view all the answers

What is a function of the structural proteins in viruses?

<p>Facilitate transfer of viral nucleic acid (A)</p> Signup and view all the answers

Which statement about the structure of paxoviruses is true?

<p>Brick-shaped with ridges on the external surface (C)</p> Signup and view all the answers

What determines the antigenic characteristics of a virus?

<p>Structural proteins (A)</p> Signup and view all the answers

Why is it not possible for 'empty' helical particles to form?

<p>Regular, periodic interaction between capsid protein and nucleic acid (A)</p> Signup and view all the answers

What is recommended if rubella is diagnosed in the first trimester of pregnancy?

<p>Immediate pregnancy termination (A)</p> Signup and view all the answers

Why is accurate laboratory identification of the infecting virus necessary for the use of antiviral agents?

<p>To ensure effectiveness of the antiviral agent (C)</p> Signup and view all the answers

In chronic diseases like HIV and hepatitis B virus, what is required to make decisions about therapy initiation?

<p>Full understanding of laboratory findings (D)</p> Signup and view all the answers

How are drug combinations for patients with viral infections typically selected?

<p>According to the drug resistance profile of the infecting virus strain (D)</p> Signup and view all the answers

What is the purpose of virus load testing in monitoring response to therapy?

<p>To monitor the response and adjust therapy as needed (B)</p> Signup and view all the answers

Why might blood banks screen for viruses like HIV and hepatitis B and C?

<p>To prevent spread through blood transfusions (C)</p> Signup and view all the answers

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