Viroids, Virusoids, and Prions

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Questions and Answers

Which of the following requires a helper virus for infection?

  • Virusoid (correct)
  • Bacteriophage
  • Prion
  • Viroid

What type of molecule primarily makes up a prion?

  • RNA
  • Lipid
  • Protein (correct)
  • DNA

What is a key characteristic of prions that distinguishes them from viruses?

  • They are easily destroyed by autoclaving.
  • They contain nucleic acid.
  • They consist of only protein. (correct)
  • They only infect plants.

Which human disease is associated with a virusoid?

<p>Hepatitis D (C)</p> Signup and view all the answers

Which of the following pathogens primarily infects plants?

<p>Virusoids (A)</p> Signup and view all the answers

What is a common name for the diseases caused by prions?

<p>Transmissible spongiform encephalopathies (D)</p> Signup and view all the answers

Which pathogen does not need a helper virus to infect a host?

<p>Viroid (C)</p> Signup and view all the answers

What process is ineffective in eliminating prions?

<p>Autoclaving (B)</p> Signup and view all the answers

Which of the following is an example of a prion disease?

<p>Mad cow disease (D)</p> Signup and view all the answers

Which of the following requires simultaneous infection with hepatitis B?

<p>Hepatitis D virus (A)</p> Signup and view all the answers

What are prions?

<p>Infectious proteins (D)</p> Signup and view all the answers

What is the main type of disease caused by prions?

<p>Brain disease (B)</p> Signup and view all the answers

Which of the following is a characteristic of viroids?

<p>They cause plant diseases (B)</p> Signup and view all the answers

What term describes normal animal proteins that become infectious after misfolding?

<p>Prions (A)</p> Signup and view all the answers

Which of these is NOT a characteristic of prions?

<p>They are easily destroyed by autoclaving (D)</p> Signup and view all the answers

A patient with Hepatitis D must also be infected with which other disease?

<p>Hepatitis B (B)</p> Signup and view all the answers

Which of the following is a plant virus?

<p>Hepatitis D (A)</p> Signup and view all the answers

What do viroids and virusoids infect?

<p>Plants (C)</p> Signup and view all the answers

When do normal animal proteins become infectious?

<p>When abnormally folded (A)</p> Signup and view all the answers

What is another name for mad cow disease?

<p>Transmissible spongiform encephalopathy (A)</p> Signup and view all the answers

What causes transmissible spongiform encephalopathies?

<p>Prions (D)</p> Signup and view all the answers

Which of the following does not have nucleic acid?

<p>Prions (A)</p> Signup and view all the answers

What part of the body do transmissible spongiform encephalopathies affect?

<p>Brain (D)</p> Signup and view all the answers

What is the role of a helper virus?

<p>To assist in virusoid infection (D)</p> Signup and view all the answers

Which disease is transmitted by prions?

<p>Mad cow disease (D)</p> Signup and view all the answers

What is the Delta agent?

<p>A virusoid (C)</p> Signup and view all the answers

Which term describes infectious particles made of protein?

<p>Prions (C)</p> Signup and view all the answers

What type of diseases are kuru and mad cow disease?

<p>Prion diseases (C)</p> Signup and view all the answers

Which factor is irrelevant when determining if a disease is caused by a prion?

<p>DNA presence (B)</p> Signup and view all the answers

What must a patient be simultaneously infected with to contract Hepatitis D?

<p>Hepatitis B (C)</p> Signup and view all the answers

What is the primary effect of transmissible spongiform encephalopathies on the brain?

<p>Sponge-like degeneration (D)</p> Signup and view all the answers

Which molecule is affected in prion diseases?

<p>Protein (C)</p> Signup and view all the answers

What must virusoids rely on for infections?

<p>Helper viruses (A)</p> Signup and view all the answers

Which particle is composed solely of abnormally folded proteins?

<p>Prion (C)</p> Signup and view all the answers

What makes prions resistant to autoclaving?

<p>Unique protein structure (A)</p> Signup and view all the answers

Which characteristic is unique to viroids?

<p>Cause plant diseases (B)</p> Signup and view all the answers

What is required for a Prion to be infectious?

<p>Abnormal folding (A)</p> Signup and view all the answers

What term describes an infectious agent that requires simultaneous co-infection of Hepatitis B?

<p>Virusoid (C)</p> Signup and view all the answers

Flashcards

Viroids

Infectious agents that cause plant diseases and do not require a helper virus.

Virusoids

RNA sequences that require a helper virus to infect a host cell.

Hepatitis D virus

The Delta agent (virus) which is actually one of the plant viruses (viroids) that can infect humans; patient has to be simultaneously infected with hepatitis B.

Prions

Infectious particles composed of abnormally folded proteins.

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Do prions lack nucleic acid?

Prions lack this.

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Transmissible Spongiform Encephalopathies

A group of fatal neurodegenerative diseases caused by prions that cause spongy lesions in the brain.

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Study Notes

  • Viroids do not need a helper virus
  • Viroids cause plant diseases
  • Virusoids need a helper virus
  • Virusoids are generally associated with plant infection
  • Hepatitis D virus, also called Delta agent, is a virus that is actually one of the plant viruses (viroids) which can infect humans
  • To be infected with Hepatitis D, the patient has to be simultaneously infected with hepatitis B
  • Prions are normal animal proteins that become infectious particles when abnormally folded
  • Prions lack nucleic acid
  • Prions are not affected by autoclaving
  • Diseases caused by prions are called transmissible spongiform encephalopathies, examples are mad cow disease and kuru

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