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Questions and Answers
What occurs during the protein synthesis of a virus?
What occurs during the protein synthesis of a virus?
- Capsid proteins are decomposed
- Endoplasmic reticulum generates new cells
- Viral RNA genomes are assembled into viral RNA (correct)
- Viral RNA genomes are destroyed
How are mature nucleocapsids formed in viruses?
How are mature nucleocapsids formed in viruses?
- Through the plasma membrane
- Via nuclear fusion
- By the breakdown of host DNA
- Through the endoplasmic reticulum membrane (correct)
Which of the following best describes the transmission of Dengue virus?
Which of the following best describes the transmission of Dengue virus?
- Contact with contaminated surfaces
- Direct contact with infected blood
- Transmission through infected mosquitoes (correct)
- Inhalation of airborne particles
What happens during the viremia phase of Dengue virus infection?
What happens during the viremia phase of Dengue virus infection?
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What type of genetic material do adenoviruses have?
What type of genetic material do adenoviruses have?
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What is the function of hexon proteins in adenoviruses?
What is the function of hexon proteins in adenoviruses?
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Study Notes
Protein Synthesis
- Newly synthesized viral RNA genomes are assembled into viral RNA, including structural proteins.
Assembly
- Viral genomes and capsid proteins assemble together into mature nucleocapsids through the endoplasmic reticulum (ER) membrane.
- Host cell acquires envelope by exocytosis.
Pathogenesis of Dengue Virus
- Dengue virus is primarily transmitted to humans through the bite of infected mosquitoes.
- Virus enters the body and targets immature cells.
- Viremia occurs, where the virus circulates in the bloodstream, usually within 4-10 days after infection.
- Dengue symptoms include widespread infection, high fever, severe headache, eye pain, joint muscle pain, rash, and mild bleeding.
Adenovirus
- Adenoviruses are medium-sized (90-100 nm), non-enveloped viruses with double-stranded DNA.
- There are more than 50 types of distinct adenoviruses that can cause infections in humans.
- The capsid is composed of protein subunits called capsomeres.
- Hexon proteins are the most distinct adenovirus proteins.
Adenovirus Replication
- Attachment: Adenovirus attaches to specific receptors on a host cell.
- Entry: The virus gets engulfed by the host cell into an endosome.
- Genome: The genome is likely encoded by more than 50 distinct adenoviruses.
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Description
Explore the process of viral replication, including protein synthesis and assembly, and the pathogenesis of Dengue virus.
