Viral Multiplication and Antiviral Agents

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18 Questions

What is the target of Nucleoside analogs in viral multiplication?

Viral DNA and RNA polymerase

What is the primary disadvantage of chemoprophylaxis in preventing viral infections?

It can also affect normal host cells

What type of vaccine is prepared by heat or chemical inactivation of whole virions?

Killed virus vaccine

What is the function of interferon in preventing viral infections?

It activates immune cells to fight viral infections

What is the target of Indinavir and Siquinavir in viral multiplication?

Cleavage of precursor polypeptide

What is the advantage of using Virion subunit vaccine over killed virus vaccine?

It has fewer risks of adverse reactions

What is the outcome when there is no antigen that binds to the antibody in a hemagglutination reaction?

Hemolysis occurs

Which of the following is NOT a method for diagnosing viral diseases?

X-ray imaging

What is the purpose of adding enzyme-linked anti-HISG in the ELISA test?

To bind to the bound antibody

What is a challenge in treating viral diseases?

The virus is spread throughout the body by the time symptoms appear

What is the result of adding enzyme substrate in the ELISA test?

A color change is produced

Which of the following is a reason for the emergence of drug-resistant mutants in viral diseases?

Mutants of herpes virus resistant to Acyclovir have been recovered from patients

What is the primary consideration when selecting a specimen type for viral diagnosis?

The clinical and epidemiological considerations

When is it best to collect a specimen for viral diagnosis?

As early as possible, within the first 4 days of symptom onset

What type of material should be avoided when collecting a viral specimen?

Cotton swab with calcium alginate

Why is it recommended to use viral transport medium for most specimens?

It contains a protein stabilizer and antibiotics

What should be done if there is a delay in processing the specimen?

Hold the specimen at 4°C

What is the primary purpose of including antibiotics in viral transport medium?

To prevent contamination during transport

This quiz covers the site of action of antiviral agents in viral multiplication, including early events, nucleic acid synthesis, protein synthesis, and more. It also touches on prevention of viral infections through chemoprophylaxis.

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