Viral Infections
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Questions and Answers

Which of the following viruses is a retrovirus?

  • Human Immunodeficiency Virus (HIV) (correct)
  • Cytomegalovirus (CMV)
  • Avian Influenza A (H5N1)
  • Respiratory Syncytial Virus (RSV)
  • Which of the following drugs interrupts viral DNA replication?

  • Acyclovir (Zovirax) (correct)
  • Ganciclovir (Cytovene)
  • Valganciclovir (Valcyte)
  • None of the above
  • Which of the following viruses causes fever blisters or cold sores on the lips, mouth, and face?

  • Cytomegalovirus (CMV)
  • Respiratory Syncytial Virus (RSV)
  • Herpes Simplex Virus (HSV) (correct)
  • Avian Influenza A (H5N1)
  • Which drug is used to prevent future viral outbreaks of genital herpes?

    <p>Acyclovir</p> Signup and view all the answers

    When administering ganciclovir for Cytomegalovirus retinitis, what is the most important consideration?

    <p>Assess client's vision after administration</p> Signup and view all the answers

    Which drug is used to treat Respiratory Syncytial Virus (RSV) in children?

    <p>Ribavirin</p> Signup and view all the answers

    What is the most likely cause of severe upper abdominal pain in a client taking lamivudine?

    <p>Pancreatitis</p> Signup and view all the answers

    Which symptom may indicate the client is developing lactic acidosis?

    <p>B. severe upper abdominal pain</p> Signup and view all the answers

    For which delayed hypersensitivity reaction should the nurse educate the client who has been taking efavirenz for about 1 week?

    <p>D. Stevens-Johnson syndrome</p> Signup and view all the answers

    Which drug is given subcutaneously for treatment of HIV?

    <p>C. enfuvirtide</p> Signup and view all the answers

    Match the following viruses with their associated conditions:

    <p>Herpes Simplex Virus (HSV) = Fever blisters or cold sores on lips, mouth, face Human Immunodeficiency Virus (HIV) = Incorporates viral DNA into host’s Respiratory Syncytial Virus (RSV) = Viral Hepatitis Cytomegalovirus (CMV) = CMV retinitis</p> Signup and view all the answers

    Match the following drugs with their corresponding viruses they treat:

    <p>Acyclovir (Zovirax) = Herpes simplex virus (HSV) Ganciclovir (Cytovene) = CMV Valganciclovir (Valcyte) = CMV Efavirenz = HIV</p> Signup and view all the answers

    Match the following drugs with their corresponding mechanisms of action:

    <p>Acyclovir (Zovirax) = Interrupts viral DNA replication Ganciclovir (Cytovene) = Inhibits viral DNA synthesis Valganciclovir (Valcyte) = Inhibits viral DNA synthesis Efavirenz = Incorporates viral DNA into host’s</p> Signup and view all the answers

    Match the following drugs with their correct prototypes:

    <p>Ribavirin = RSV in children Oseltamivir phosphate = Influenza in patients &gt; 1 year old Lamivudine = Chronic Hepatitis B, off-label for HIV Zidovudine = HIV, prevents HIV transmission from mother to fetus</p> Signup and view all the answers

    Match the following viruses with their correct transmission routes:

    <p>Hepatitis A = Fecal-oral route, close contact with infected person Hepatitis B = Contaminated blood, other body fluids Hepatitis C = Mostly same as Hepatitis B HIV = Sex, injection, mother to fetus</p> Signup and view all the answers

    Match the following symptoms with the correct conditions or side effects:

    <p>Severe upper abdominal pain with guarding = Pancreatitis Muscle aches, pains, fatigue, fever, nausea/vomiting, headache, diarrhea, shivering = Influenza Nasal flaring, signs of respiratory distress = RSV in children Lactic acidosis, hepatomegaly = Side effects of certain HIV drugs</p> Signup and view all the answers

    Match the following drugs with their correct mechanisms of action:

    <p>Ribavirin = Interferes with DNA and RNA replication Oseltamivir phosphate = Does not allow new viruses to escape cell Lamivudine = Incorporates into the viral DNA and terminates it Zidovudine = Incorporates into viral DNA and terminates</p> Signup and view all the answers

    Match the following HIV drugs with their mechanisms of action:

    <p>Saquinavir mesylate (Invirase) = Prevents viral maturation Raltegravir (Isentress) = Blocks enzyme HIV integrase, which would normally make more viruses Enfuvirtide (Fuzeon) = Prevents HIV from entering cell Maraviroc (Selzentry) = Prevents HIV from entering cell</p> Signup and view all the answers

    Match the following HIV drugs with their nursing considerations:

    <p>Saquinavir mesylate (Invirase) = Must monitor for QT prolongation, Take within 2 hours of a meal Raltegravir (Isentress) = Only for strains resistant to multiple antiretroviral drugs Enfuvirtide (Fuzeon) = Given as subcutaneous injection, Must have already received other antiretroviral agents Maraviroc (Selzentry) = Not for patients with low kidney function, May cause hepatotoxicity and/or allergy symptoms</p> Signup and view all the answers

    True or false: Viruses are extracellular parasites.

    <p>False</p> Signup and view all the answers

    True or false: Retroviruses have DNA which must be converted to RNA first.

    <p>False</p> Signup and view all the answers

    True or false: HIV is a retrovirus.

    <p>True</p> Signup and view all the answers

    True or false: Acyclovir is prescribed to boost the activity of other drugs.

    <p>False</p> Signup and view all the answers

    True or false: Ganciclovir should be administered on an empty stomach when treating Cytomegalovirus retinitis.

    <p>False</p> Signup and view all the answers

    True or false: Ribavirin is a drug used to treat Influenza.

    <p>False</p> Signup and view all the answers

    True or false: Lamivudine is used to treat Chronic Hepatitis C.

    <p>False</p> Signup and view all the answers

    Lactic acidosis is a potential symptom of low granulocyte count.

    <p>False</p> Signup and view all the answers

    Lactic acidosis is a potential symptom of severe upper abdominal pain.

    <p>False</p> Signup and view all the answers

    The nurse should educate the client taking efavirenz for about 1 week about anaphylaxis as a delayed hypersensitivity reaction.

    <p>False</p> Signup and view all the answers

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