Viral Genetics: Mutation and Recombination

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What role does the nature of the viral genome play in viral genetics?

It influences the likelihood of mutations occurring

What is the main reason why DNA viruses tend to be more genetically stable than RNA viruses?

DNA repair mechanisms exist in the host cell

Why are some RNA viruses remarkably invariant in nature despite having a high mutation rate?

They are not precisely adapted for transmission and replication

What are the rare forms of the bases that can exist in solution and lead to mispairing?

<p>Imino forms and enol forms</p> Signup and view all the answers

Which type of mutations are induced by agents acting directly on bases, such as nitrous acid?

<p>Induced mutations</p> Signup and view all the answers

How does the rapid growth of viruses contribute to the occurrence of mutations?

<p>More chance of mutations occurring over a short time period</p> Signup and view all the answers

What role does the nature of the viral genome play in the genetics of the virus?

<p>Plays an important role in the genetics of the virus</p> Signup and view all the answers

Why are DNA viruses generally more genetically stable than RNA viruses?

<p>There are error correction mechanisms in the host cell for DNA repair</p> Signup and view all the answers

What are the rare forms of the bases that can exist in solution and lead to mispairing?

<p>The rare imino forms for A and C, and the rare enol forms for G and T</p> Signup and view all the answers

Why are some RNA viruses remarkably invariant in nature despite having a high mutation rate?

<p>Precisely adapted for transmission and replication</p> Signup and view all the answers

What is the main reason for DNA viruses to be more genetically stable than RNA viruses?

<p>DNA viruses have error correction mechanisms in the host cell for DNA repair</p> Signup and view all the answers

Why are some RNA viruses remarkably invariant in nature despite having a high mutation rate?

<p>They have a precisely adapted mechanism for replication and transmission</p> Signup and view all the answers

What forms of the bases can exist in solution and lead to mispairing?

<p>Rare imino forms and rare enol forms</p> Signup and view all the answers

Which type of mutations are induced by agents acting directly on bases, such as nitrous acid?

<p>Induced mutations</p> Signup and view all the answers

What can lead to mutations during viral replication?

<p>Incorporation of tautomeric forms of the bases</p> Signup and view all the answers

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