Antiviral Drugs Quiz

What is a characteristic of viruses?

When do clinical symptoms typically appear in viral diseases?

What is the nature of antiviral drugs?

Which virus infects only people?

What are the surface proteins of Influenza A virus used for?

What is the preferred approach for dealing with viral respiratory tract infections according to the text?

What is the mechanism of action of neuraminidase inhibitors?

How are Oseltamivir and Zanamivir mainly excreted from the body?

What is the preferred route of administration for Zanamivir?

What are the adverse effects of Oseltamivir?

What adverse effect is associated with Zanamivir?

What leads to resistance to neuraminidase inhibitors?

Nausea and vomiting associated with Oseltamivir can be minimized by taking it on an empty stomach.

Zanamivir may cause respiratory discomfort, especially in patients with airway diseases.

Mutations in the neuraminidase enzyme can lead to resistance to both Oseltamivir and Zanamivir.

What is the mechanism of action of adamantane antivirals?

When is the administration of adamantane antivirals most effective against Influenza A viruses?

How is Amantadine excreted from the body?

What is the primary use of Ribavirin?

Which type of viruses is Ribavirin active against?

In addition to RSV infections, what other virus can Ribavirin be effective against when combined with other medications?

Ribavirin is active against both RNA and DNA viruses.

Ribavirin can be used for the treatment of severe RSV bronchiolitis or pneumonia in children and infants.

What is the primary route of excretion for ribavirin and its metabolites?

How does ribavirin inhibit the replication of RNA and DNA viruses?

What is the preferred route of administration for ribavirin in the treatment of RSV infection?

What is a contraindication for the use of ribavirin?

What adverse effect may aerosolized ribavirin cause?

What adverse effect is dose dependent and transient when using ribavirin?

Which hepatitis virus is an RNA virus?

Which is the following correct goal of chronic HBV therapy expect?

What is the primary use of interferon alpha as mentioned in the text?

What is the result of interferon alpha's binding to specific cell membrane receptors?

Why is the use of interferon alpha uncommon, according to the text?

How is Lamivudine activated within the host cell?

What limits the chronic therapy of Lamivudine?

Ribavirin is primarily used for the treatment of HIV infections.

Chronic therapy with Lamivudine is limited due to the emergence of Lamivudine resistant HBV.

What is the primary use of adefovir?

Adefovir dipivoxil is a prodrug of Adefovir.

Ribavirin is primarily used for the treatment of HCV infections.

Zanamivir may cause respiratory discomfort, especially in patients with airway diseases.

Adefovir is primarily excreted in the urine. True or False?

Ribavirin is effective against both RNA and DNA viruses. True or False?

Lamivudine is limited in chronic therapy due to the emergence of Lamivudine resistant HBV. True or False?

What is the primary reason for the limited chronic therapy of Lamivudine?

What effect does Entecavir have on HIV?

Entecavir is activated by host cell kinases into triphosphate form. True or False?

Adefovir is primarily excreted in the urine. True or False?

Ribavirin is effective against both RNA and DNA viruses. True or False?

Entecavir is excreted primarily in the urine. True or False?

Adverse effects of Entecavir include headache, fatigue, and dizziness. True or False?

Ribavirin is effective against both RNA and DNA viruses. True or False?

Which adverse effect is commonly associated with Tenofovir?

What is the primary route of excretion for Tenofovir and its metabolites?

What is the mechanism of action of Tenofovir against HBV?

Tenofovir is activated by host cell kinases to diphosphate form. True or False?

Entecavir is primarily excreted in the urine. True or False?

Ribavirin is effective against both RNA and DNA viruses. True or False?

What is the primary route of administration for Telbivudine in the treatment of HBV?

What is the mechanism of action of Telbivudine against HBV?

What is the primary route of administration for Telbivudine in the treatment of HBV?

What is the primary adverse effect associated with Telbivudine?

What is the primary target of drugs used to treat Hepatitis C?

What is the mechanism of action of antiviral drugs targeting HCV RNA polymerase?

How is Sofosbuvir activated within the host cell?

Which medication is often combined with Sofosbuvir in the treatment of Hepatitis C?

What is the route of elimination for Sofosbuvir from the body?

What is the mechanism of action of Dasa buvir?

What is the primary route of excretion for Entecavir and its metabolites?

What is the characteristic of Adefovir's excretion from the body?

How are NS34A serine protease inhibitors administered in the treatment of Hepatitis C?

NS34A serine protease inhibitors prevent HCV RNA replication. True or False?

Ribavirin is administered with NS34A protease inhibitors. True or False?

NS5A replication complex inhibitors are metabolized by CYP 450 isoenzymes. True or False?

Ribavirin is primarily used for the treatment of HIV infections. True or False?

Which phase of viral infections are HSV and VZV antiviral drugs effective against?

What diseases are caused by HSV and VZV infections?

Which condition is NOT treated using antiviral drugs according to the text?

Which virus infections are Acyclovir active against?

What is the primary route of excretion for Entecavir and its metabolites?

What is the mechanism of action of NS34A serine protease inhibitors used in the treatment of Hepatitis C?

Which viruses are Acyclovir active against?

How does Acyclovir act in infected cells?

What is the primary route of administration for Acyclovir?

Acyclovir is active against HSV 1, HSV 2, and VZV?

Acyclovir is primarily excreted in the urine?

Ribavirin is primarily used for the treatment of HIV infections?

What is the primary route of administration for topical Acyclovir in the treatment of cold sores?

Which type of infections is Acyclovir most effective against?

What is the primary route of excretion for Acyclovir and its metabolites?

What adverse effects are associated with the intravenous route of Acyclovir administration?

What is the primary cause of resistance to Acyclovir in HSV or VZV infections?

Which of the following is True adverse effect is commonly associated with the oral administration of Acyclovir ecxept?

How is Valacyclovir primarily converted in the body after oral administration?

What type of infections are Ganciclovir/Valganciclovir primarily used for?

What is the primary route of administration for Ganciclovir and Valganciclovir?

Valacyclovir is rapidly converted into acyclovir after oral administration.

Ganciclovir/Valganciclovir have a similar mechanism of action as acyclovir/valacyclovir.

Ribavirin is primarily used for the treatment of HIV infections.

What is the primary target of antiretroviral agents in the treatment of HIV infection?

What is the main cause of immunosuppression in patients with HIV infection?

Which of the following is a nucleoside reverse transcriptase inhibitor (NRTI) used in the initial therapy for HIV infection?

How are NRTIs activated within the host cell?

Tenofovir is activated to the triphosphate form by host cell kinases. True or False?

NRTIs have low affinity to host cell DNA polymerase. True or False?

NRTIs are primarily excreted renally, except for abacavir which is hepatically eliminated. True or False?

Abacavir hypersensitivity can present with fever, fatigue, rash, GI disturbances, and respiratory distress. True or False?

Toxicities due to inhibition of mitochondrial DNA polymerase gamma include lactic acidosis with hepatic steatosis and lipodystrophy. True or False?

What is the primary route of administration for Abacavir?

Which adverse effect is associated with NRTIs due to inhibition of mitochondrial DNA polymerase gamma?

What is the primary route of excretion for zidovudine and most NRTIs?

Which of the following is a common adverse effect associated with Abacavir?

What is the primary route of administration for Tenofovir in its treatment of HIV infection?

NRTIs can cause lactic acidosis with hepatic steatosis and lipodystrophy. True or False?

Which of the following is NOT a recommended NNRTI in initial antiretroviral regimens?

What is the 2nd generation NNRTI active against HIV strains resistant to 1st generation NNRTIs?

Which NNRTI is specifically recommended for patients with swallowing difficulty due to its small tablet form?

What is the primary mechanism of action of NNRTIs and PIs in the treatment of HIV infection?

What is the main requirement for boosting the bioavailability of PIs in combination therapy?

Which antiretroviral drug blocks the CCR5 coreceptor to prevent HIV entry?

What adverse effect is associated with the SC injection of Enfuvirtide?

Which antiretroviral drug binds to the viral gp41 and is required for entry into CD4 cells?

Which class of antiretroviral drugs inhibits the insertion of proviral DNA into the host cell genome?

Which adverse effects are commonly associated with the use of Integrase inhibitors?

How is Tenofovir primarily excreted from the body?