Introduction to Clinical pathology
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Questions and Answers

Which type of pathology involves the care of patients who are still alive?

  • Necropsy
  • Histopathology
  • Anatomic pathology
  • Clinical pathology (correct)

    • Which subspecialty in pathology focuses on laboratory technology for the diagnosis and prevention of disease?

  • Histopathology
  • Necropsy
  • Anatomic pathology
  • Clinical pathology (correct)

    • Which anticoagulant is commonly used for haematology and clinical chemistry tests?

  • Citrate
  • Fluoride-oxalate
  • Heparin
  • EDTA (correct)

    • Which anticoagulant is used to measure the ability of blood to clot and is reversible?

    <p>Citrate</p> Signup and view all the answers

    Which component of blood is removed in serum, allowing for the measurement of fibrinogen?

    <p>Fibrin</p> Signup and view all the answers

    Which anticoagulant is commonly used for exotics and can result in a high erroneous potassium level?

    <p>EDTA</p> Signup and view all the answers

    Which anticoagulant prevents glucose from being metabolized away in glucose tests?

    <p>Fluoride-oxalate</p> Signup and view all the answers

    Which anticoagulant is irreversible and works by holding onto calcium?

    <p>EDTA</p> Signup and view all the answers

    Which component of blood is used as a marker of inflammation in some species?

    <p>Fibrinogen</p> Signup and view all the answers

    Which type of pathology involves the examination of deceased animals?

    <p>Necropsy</p> Signup and view all the answers

    What can cause a haemolysed sample?

    <p>All of the above</p> Signup and view all the answers

    What effect does lipaemia have on plasma/serum values?

    <p>Increases values of some compounds</p> Signup and view all the answers

    What is the main purpose of quality control in laboratory analysis?

    <p>To ensure the validity of the result</p> Signup and view all the answers

    What is the assumption made in internal quality control?

    <p>The results are within 2 standard deviations from the historic mean</p> Signup and view all the answers

    What are the three main factors considered in the validation of an analytical technique?

    <p>Precision, accuracy, and specificity</p> Signup and view all the answers

    What is the effect of haemolysis on colorimetric tests?

    <p>It interferes with colorimetric tests</p> Signup and view all the answers

    What is the main source of variation and errors in laboratory results?

    <p>All of the above</p> Signup and view all the answers

    What are the possible causes of coloration in plasma samples?

    <p>Haemolysis, bilirubin (icteric), lipid</p> Signup and view all the answers

    How does haemolysis affect plasma/serum values?

    <p>It increases the values of compounds/enzymes due to their higher concentration in the RBC</p> Signup and view all the answers

    What are the main changes observed in plasma/serum values in the presence of lipaemia?

    <p>Increase in total lipid, triglycerides, and cholesterol</p> Signup and view all the answers

    What are the three main types of errors in lab results?

    <p>Pre-analytical, analytical, and post-analytical</p> Signup and view all the answers

    What is the difference between clinical pathology and anatomic pathology?

    <p>Clinical pathology focuses on laboratory procedures for establishing a diagnosis and/or prognosis, monitoring treatment in sick animals, and monitoring animal health. Anatomic pathology involves the examination of deceased animals through surgical pathology (biopsy) and histopathology.</p> Signup and view all the answers

    What anticoagulant is commonly used for haematology and clinical chemistry tests?

    <p>EDTA (exotics - lithium heparin full blood)</p> Signup and view all the answers

    What is the effect of lipaemia on plasma/serum values?

    <p>Lipaemia can cause erroneous high results for some analytes, such as glucose and cholesterol.</p> Signup and view all the answers

    What are the main purposes of anticoagulants in laboratory analysis?

    <p>Anticoagulants work by preventing blood clotting, allowing for the measurement of specific analytes and preventing the activation of fibrinogen. They also help to separate plasma or serum from solid components of the blood.</p> Signup and view all the answers

    How does EDTA affect calcium levels in blood samples?

    <p>EDTA removes calcium from blood samples, leading to a negative low calcium result.</p> Signup and view all the answers

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