Introduction to Clinical pathology

Which type of pathology involves the care of patients who are still alive?

Clinical pathology

Which subspecialty in pathology focuses on laboratory technology for the diagnosis and prevention of disease?

Clinical pathology

Which anticoagulant is commonly used for haematology and clinical chemistry tests?

EDTA

Which anticoagulant is used to measure the ability of blood to clot and is reversible?

Citrate Signup and view all the answers

Which component of blood is removed in serum, allowing for the measurement of fibrinogen?

Fibrin Signup and view all the answers

Which anticoagulant is commonly used for exotics and can result in a high erroneous potassium level?

EDTA Signup and view all the answers

Which anticoagulant prevents glucose from being metabolized away in glucose tests?

Fluoride-oxalate Signup and view all the answers

Which anticoagulant is irreversible and works by holding onto calcium?

EDTA Signup and view all the answers

Which component of blood is used as a marker of inflammation in some species?

Fibrinogen Signup and view all the answers

Which type of pathology involves the examination of deceased animals?

Necropsy Signup and view all the answers

What can cause a haemolysed sample?

All of the above Signup and view all the answers

What effect does lipaemia have on plasma/serum values?

Increases values of some compounds Signup and view all the answers

What is the main purpose of quality control in laboratory analysis?

To ensure the validity of the result Signup and view all the answers

What is the assumption made in internal quality control?

The results are within 2 standard deviations from the historic mean Signup and view all the answers

What are the three main factors considered in the validation of an analytical technique?

Precision, accuracy, and specificity Signup and view all the answers

What is the effect of haemolysis on colorimetric tests?

It interferes with colorimetric tests Signup and view all the answers

What is the main source of variation and errors in laboratory results?

All of the above Signup and view all the answers

What are the possible causes of coloration in plasma samples?

Haemolysis, bilirubin (icteric), lipid Signup and view all the answers

How does haemolysis affect plasma/serum values?

It increases the values of compounds/enzymes due to their higher concentration in the RBC Signup and view all the answers

What are the main changes observed in plasma/serum values in the presence of lipaemia?

Increase in total lipid, triglycerides, and cholesterol Signup and view all the answers

What are the three main types of errors in lab results?

Pre-analytical, analytical, and post-analytical Signup and view all the answers

What is the difference between clinical pathology and anatomic pathology?

Clinical pathology focuses on laboratory procedures for establishing a diagnosis and/or prognosis, monitoring treatment in sick animals, and monitoring animal health. Anatomic pathology involves the examination of deceased animals through surgical pathology (biopsy) and histopathology. Signup and view all the answers

What anticoagulant is commonly used for haematology and clinical chemistry tests?

EDTA (exotics - lithium heparin full blood) Signup and view all the answers

What is the effect of lipaemia on plasma/serum values?

Lipaemia can cause erroneous high results for some analytes, such as glucose and cholesterol. Signup and view all the answers

What are the main purposes of anticoagulants in laboratory analysis?

Anticoagulants work by preventing blood clotting, allowing for the measurement of specific analytes and preventing the activation of fibrinogen. They also help to separate plasma or serum from solid components of the blood. Signup and view all the answers

How does EDTA affect calcium levels in blood samples?

EDTA removes calcium from blood samples, leading to a negative low calcium result. Signup and view all the answers