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Clinical Pathology and Laboratory Medicine: Leucocytosis Types

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Clinical Pathology and Laboratory Medicine: Leucocytosis Types

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Questions and Answers

Which of the following is NOT one of the major types of leucocytosis mentioned in the text?

Inflammatory

Eosinophilic (correct)

Catecholamine-associated

Glucocorticoid-associated

What is the reason for poor prognosis indicated by the finding of 'Degenerative left shift' in leucogram?

Overwhelming tissue demands (exceeds bone marrow production) (correct)

Accelerated production of toxic neutrophils

Excessive numbers of eosinophils due to marked inflammatory stimulus

Excessive numbers of neutrophils due to marked inflammatory stimulus

Which newer assays are being used to differentiate the different forms of leucocyte neoplasia and to distinguish between hyperplastic and neoplastic proliferations?

Northern blotting and FISH

Western blotting and immunohistochemistry

Flow cytometry and PARR (correct)

ELISA and PCR

What is the reason for poor prognosis indicated by the presence of 'Leukemoid reaction' in leucogram findings?

Excessive numbers of neutrophils due to marked inflammatory stimulus Signup and view all the answers

What distinguishes the major types of leucocytosis mentioned in the text?

Leucocyte concentrations and associations with other laboratory data Signup and view all the answers

What is a characteristic of degenerative left shift?

Bone marrow is unable to maintain an adequate response Signup and view all the answers

What is a characteristic of toxic change in neutrophils?

Dysmature neutrophils released due to overwhelming demand Signup and view all the answers

What does a regenerative left shift indicate?

An adequate response Signup and view all the answers

What is a key characteristic of leukemoid reaction?

Marked leucocytosis that mimics neoplasia Signup and view all the answers

What differentiates segmented neutrophils from band neutrophils?

Presence of focal narrowing (indentation) of the nucleus with loss of parallel sides Signup and view all the answers