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Vinca Alkaloids and Vinorelbine

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Questions and Answers

What is a characteristic of the Vinca alkaloids?

They are alkylating agents

They are cytotoxins with identical therapeutic indications

They are microtubule inhibitors (correct)

They are synthetic anticancer drugs

Which of the following statements is true about the Vinca alkaloids?

They are structurally similar but have different therapeutic indications (correct)

They are not used as anticancer drugs

They have identical therapeutic indications

They are only toxic to cancer cells

What class of anticancer drugs do the Vinca alkaloids belong to?

Plant-derived anticancer drugs (correct)

Cytotoxins

Hormone antagonists

Alkylating agents

Which of the following is NOT a characteristic of the Vinca alkaloids?

They are alkylating agents Signup and view all the answers

What is the mechanism of action of the Vinca alkaloids?

They inhibit the formation of microtubules Signup and view all the answers

What is the common name for the class of compounds that vinorelbine belongs to?

Vinca alkaloids Signup and view all the answers

Which of the following properties is characteristic of vinorelbine compared to other Vinca alkaloids?

It is a less neurotoxic agent Signup and view all the answers

What is the primary mechanism of action of vinorelbine and other Vinca alkaloids?

Inhibiting microtubule formation Signup and view all the answers

Which of the following classes of anticancer drugs does vinorelbine belong to?

Microtubule inhibitors Signup and view all the answers

What is the origin of vinorelbine and other Vinca alkaloids?

Plant-derived compounds Signup and view all the answers

What is the phase of the cell cycle where the drugs are active?

G2/M phase Signup and view all the answers

What is the effect of the drugs on microtubules?

Stabilization and polymerization of microtubules Signup and view all the answers

What is the difference between the drugs and Vinca alkaloids in terms of their action on microtubules?

The drugs promote polymerization and stabilization, whereas Vinca alkaloids promote disassembly Signup and view all the answers

What class of anticancer drugs do the drugs belong to?