Vinca Alkaloids and Vinorelbine
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Vinca Alkaloids and Vinorelbine

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Questions and Answers

What is a characteristic of the Vinca alkaloids?

  • They are alkylating agents
  • They are cytotoxins with identical therapeutic indications
  • They are microtubule inhibitors (correct)
  • They are synthetic anticancer drugs

    • Which of the following statements is true about the Vinca alkaloids?

  • They are structurally similar but have different therapeutic indications (correct)
  • They are not used as anticancer drugs
  • They have identical therapeutic indications
  • They are only toxic to cancer cells

    • What class of anticancer drugs do the Vinca alkaloids belong to?

  • Plant-derived anticancer drugs (correct)
  • Cytotoxins
  • Hormone antagonists
  • Alkylating agents

    • Which of the following is NOT a characteristic of the Vinca alkaloids?

    <p>They are alkylating agents</p> Signup and view all the answers

    What is the mechanism of action of the Vinca alkaloids?

    <p>They inhibit the formation of microtubules</p> Signup and view all the answers

    What is the common name for the class of compounds that vinorelbine belongs to?

    <p>Vinca alkaloids</p> Signup and view all the answers

    Which of the following properties is characteristic of vinorelbine compared to other Vinca alkaloids?

    <p>It is a less neurotoxic agent</p> Signup and view all the answers

    What is the primary mechanism of action of vinorelbine and other Vinca alkaloids?

    <p>Inhibiting microtubule formation</p> Signup and view all the answers

    Which of the following classes of anticancer drugs does vinorelbine belong to?

    <p>Microtubule inhibitors</p> Signup and view all the answers

    What is the origin of vinorelbine and other Vinca alkaloids?

    <p>Plant-derived compounds</p> Signup and view all the answers

    What is the phase of the cell cycle where the drugs are active?

    <p>G2/M phase</p> Signup and view all the answers

    What is the effect of the drugs on microtubules?

    <p>Stabilization and polymerization of microtubules</p> Signup and view all the answers

    What is the difference between the drugs and Vinca alkaloids in terms of their action on microtubules?

    <p>The drugs promote polymerization and stabilization, whereas Vinca alkaloids promote disassembly</p> Signup and view all the answers

    What class of anticancer drugs do the drugs belong to?

    <p>Microtubule inhibitors</p> Signup and view all the answers

    What is the outcome of the drugs' action on microtubules?

    <p>Accumulation of microtubules</p> Signup and view all the answers

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