Vinca Alkaloids and Vinorelbine
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Questions and Answers

What is a characteristic of the Vinca alkaloids?

  • They are alkylating agents
  • They are cytotoxins with identical therapeutic indications
  • They are microtubule inhibitors (correct)
  • They are synthetic anticancer drugs

Which of the following statements is true about the Vinca alkaloids?

  • They are structurally similar but have different therapeutic indications (correct)
  • They are not used as anticancer drugs
  • They have identical therapeutic indications
  • They are only toxic to cancer cells

What class of anticancer drugs do the Vinca alkaloids belong to?

  • Plant-derived anticancer drugs (correct)
  • Cytotoxins
  • Hormone antagonists
  • Alkylating agents

Which of the following is NOT a characteristic of the Vinca alkaloids?

<p>They are alkylating agents (D)</p> Signup and view all the answers

What is the mechanism of action of the Vinca alkaloids?

<p>They inhibit the formation of microtubules (D)</p> Signup and view all the answers

What is the common name for the class of compounds that vinorelbine belongs to?

<p>Vinca alkaloids (C)</p> Signup and view all the answers

Which of the following properties is characteristic of vinorelbine compared to other Vinca alkaloids?

<p>It is a less neurotoxic agent (C)</p> Signup and view all the answers

What is the primary mechanism of action of vinorelbine and other Vinca alkaloids?

<p>Inhibiting microtubule formation (B)</p> Signup and view all the answers

Which of the following classes of anticancer drugs does vinorelbine belong to?

<p>Microtubule inhibitors (A)</p> Signup and view all the answers

What is the origin of vinorelbine and other Vinca alkaloids?

<p>Plant-derived compounds (B)</p> Signup and view all the answers

What is the phase of the cell cycle where the drugs are active?

<p>G2/M phase (C)</p> Signup and view all the answers

What is the effect of the drugs on microtubules?

<p>Stabilization and polymerization of microtubules (B)</p> Signup and view all the answers

What is the difference between the drugs and Vinca alkaloids in terms of their action on microtubules?

<p>The drugs promote polymerization and stabilization, whereas Vinca alkaloids promote disassembly (A)</p> Signup and view all the answers

What class of anticancer drugs do the drugs belong to?

<p>Microtubule inhibitors (B)</p> Signup and view all the answers

What is the outcome of the drugs' action on microtubules?

<p>Accumulation of microtubules (A)</p> Signup and view all the answers

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