Veterinary Pharmacology Quiz

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Questions and Answers

Why was erythropoietin prescribed for the dog in terminal renal failure?

  • For its fibrinolytic activity
  • For its ability to reduce hypertension
  • For its immunosuppressive activity
  • For its ability to stimulate red blood cell production and release (correct)

Which of the following drugs is considered a response modifier?

  • EDTA
  • Interferon (correct)
  • Streptokinase
  • Cephalosporin

Why is chloramphenicol used with extreme caution in cats and neonates?

  • It can bind with dietary calcium and become deactivated
  • It can alter developing bone, enamel, and cartilage (correct)
  • The liver is unable to metabolize chloramphenicol effectively in these animals
  • It may drastically alter gut bacterial flora, resulting in fatal diarrhea

What fatal reaction to chloramphenicol has been reported in cats and people?

<p>Aplastic anemia (A)</p> Signup and view all the answers

When are drugs such as sulfadimethoxine, sulfadiazine, and other sulfa drugs most likely to cause kidney problems?

<p>When an animal is dehydrated (B)</p> Signup and view all the answers

What are trimethoprim and ormetoprim?

<p>Agents that enhance bactericidal activity of sulfonamides (A)</p> Signup and view all the answers

What reaction should clients and veterinary professionals watch for in dogs having adverse reactions to sulfadiazine?

<p>Sudden liver failure (B)</p> Signup and view all the answers

Which antibacterial drug is also effective against protozoa such as Giardia?

<p>Metronidazole (B)</p> Signup and view all the answers

What drug is used intravenously to treat status epilepticus?

<p>Diazepam (D)</p> Signup and view all the answers

What anticonvulsant drug is converted by the liver primarily to phenobarbital, which accounts for most of its anticonvulsant activity?

<p>Primidone (C)</p> Signup and view all the answers

What traditional anticonvulsant is now being used simultaneously with phenobarbital in dogs that are nonresponsive to phenobarbital alone?

<p>Potassium bromide (A)</p> Signup and view all the answers

What drug is a respiratory stimulant?

<p>Doxapram (A)</p> Signup and view all the answers

8

<p>Expectorants (A)</p> Signup and view all the answers

Drugs used to increase airflow, through respiratory passageways narrowed by the relaxation of smooth muscle around them, are called:

<p>Bronchodilators (B)</p> Signup and view all the answers

Butorphanol and hydrocodone are examples of:

<p>Decongestants (D)</p> Signup and view all the answers

What effect do beta-receptor agonists have on the respiratory tree?

<p>Cause bronchodilatation (D)</p> Signup and view all the answers

Terbutaline, albuterol, and metaproterenol are used in veterinary medicine to:

<p>Treat feline asthma or other bronchoconstrictive diseases (D)</p> Signup and view all the answers

Flashcards

Erythropoietin Use

Prescribed for dogs in renal failure to stimulate red blood cell production.

Response Modifier

A drug that enhances the immune system's response to diseases.

Chloramphenicol Caution

Use with caution in cats and neonates due to risk of bone marrow suppression.

Fatal Reaction to Chloramphenicol

Aplastic anemia (inhibited blood cell production).

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Sulfa Drugs and Kidneys

Can lead to kidney problems, especially in dehydrated animals.

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Trimethoprim and Ormetoprim

Antibiotics combined with sulfonamides to enhance their antimicrobial efficacy.

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Adverse Reactions to Sulfadiazine

Monitor for skin reactions or fever.

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Metronidazole

Effective against protozoa like Giardia.

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Status Epilepticus

Prolonged seizure condition.

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Diazepam Use

Commonly used intravenously to treat status epilepticus.

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Primidone Action

Converted by the liver into phenobarbital, contributing to anticonvulsant properties.

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Zonisamide Use

May be used alongside phenobarbital in dogs that don't respond adequately to phenobarbital alone.

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Doxapram

Enhancing respiratory drive.

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Bronchodilators

Increase airflow through narrowed respiratory passageways by relaxing smooth muscle.

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Butorphanol and Hydrocodone

Used for pain management and cough suppression.

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Beta-Receptor Agonists

Generally induce bronchodilation.

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Terbutaline, Albuterol, Metaproterenol

Used to relieve bronchospasm in conditions like asthma or chronic bronchitis.

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Study Notes

Erythropoietin and Renal Failure in Dogs

  • Erythropoietin is prescribed for dogs in terminal renal failure to stimulate red blood cell production, counteracting anemia caused by insufficient erythropoietin production by the kidneys.

Response Modifiers

  • A response modifier is a drug that enhances the immune system's response to diseases; specific examples can vary based on treatment contexts.

Caution with Chloramphenicol

  • Chloramphenicol is used cautiously in cats and neonates due to the risk of severe adverse effects, particularly bone marrow suppression.

Fatal Reactions to Chloramphenicol

  • A fatal reaction associated with chloramphenicol has been reported in cats and humans characterized by aplastic anemia, a severe condition inhibiting the production of blood cells.

Sulfa Drugs and Kidney Issues

  • Sulfadimethoxine, sulfadiazine, and similar sulfa drugs can lead to kidney problems, particularly when used in dehydrated animals or in cases of prior kidney dysfunction.

Trimethoprim and Ormetoprim

  • Trimethoprim and ormetoprim are antibiotics often combined with sulfonamides to enhance their antimicrobial efficacy.

Adverse Reactions to Sulfadiazine

  • Clients and veterinary professionals should monitor dogs for signs of skin reactions or fever as potential adverse reactions to sulfadiazine.

Antibacterial Drug Effective Against Protozoa

  • Metronidazole is an antibacterial drug that is also effective against protozoa like Giardia.

Treatment for Status Epilepticus

  • Diazepam is commonly used intravenously to treat status epilepticus, which is a prolonged seizure condition.

Anticonvulsant Converted to Phenobarbital

  • Primidone is an anticonvulsant drug converted by the liver into phenobarbital, contributing significantly to its anticonvulsant properties.

Combined Anticonvulsant Therapy

  • Zonisamide is a traditional anticonvulsant that may be used alongside phenobarbital in dogs that do not respond adequately to phenobarbital alone.

Respiratory Stimulants

  • Doxapram is a drug classified as a respiratory stimulant, enhancing respiratory drive.

Bronchodilators

  • Drugs that increase airflow through narrowed respiratory passageways by relaxing smooth muscle are termed bronchodilators.

Opioid Examples

  • Butorphanol and hydrocodone are examples of opiate analgesics used for pain management and cough suppression in veterinary medicine.

Effect of Beta-Receptor Agonists

  • Beta-receptor agonists generally induce bronchodilation, improving airflow in animals with respiratory distress.

Veterinary Medicine Applications

  • Terbutaline, albuterol, and metaproterenol are used in veterinary medicine to relieve bronchospasm in conditions like asthma or chronic bronchitis.

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