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Questions and Answers
What is the primary mechanism leading to adverse reactions to food in dogs?
What is the primary mechanism leading to adverse reactions to food in dogs?
Which clinical sign is NOT commonly associated with food allergies in dogs?
Which clinical sign is NOT commonly associated with food allergies in dogs?
Which breed is associated with primary idiopathic seborrhea?
Which breed is associated with primary idiopathic seborrhea?
What is a KEY feature of Cytopoint's effectiveness in dogs?
What is a KEY feature of Cytopoint's effectiveness in dogs?
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Which method is used for diagnosing a food allergy in dogs?
Which method is used for diagnosing a food allergy in dogs?
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What is the primary mechanism involved in the pathogenesis of the pemphigus complex?
What is the primary mechanism involved in the pathogenesis of the pemphigus complex?
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Which of the following areas is least commonly affected by pemphigus foliaceus in cats?
Which of the following areas is least commonly affected by pemphigus foliaceus in cats?
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Which treatment option is exclusively used for cats suffering from autoimmune skin disorders?
Which treatment option is exclusively used for cats suffering from autoimmune skin disorders?
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What clinical sign may pemphigus foliaceus in cats frequently mimic due to its pustular nature?
What clinical sign may pemphigus foliaceus in cats frequently mimic due to its pustular nature?
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In the diagnosis of autoimmune skin disorders, which method is considered the most definitive?
In the diagnosis of autoimmune skin disorders, which method is considered the most definitive?
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What is a common area affected by autoimmune skin disorders?
What is a common area affected by autoimmune skin disorders?
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Which treatment is recommended for pemphigus complex in dogs?
Which treatment is recommended for pemphigus complex in dogs?
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Which of the following is indicative of hepatocutaneous syndrome?
Which of the following is indicative of hepatocutaneous syndrome?
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What is a common treatment for cases of autoimmune skin disorders?
What is a common treatment for cases of autoimmune skin disorders?
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What is one potential consequence of hepatocutaneous syndrome?
What is one potential consequence of hepatocutaneous syndrome?
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What type of lesions are often seen in autoimmune skin disorders?
What type of lesions are often seen in autoimmune skin disorders?
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Which diagnostic method is primarily used for autoimmune skin disorders?
Which diagnostic method is primarily used for autoimmune skin disorders?
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Which of these options describes a key characteristic of pemphigus foliaceus?
Which of these options describes a key characteristic of pemphigus foliaceus?
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Which of the following is a primary cause of external otitis that is least likely to affect dogs?
Which of the following is a primary cause of external otitis that is least likely to affect dogs?
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What factor may contribute to external otitis in breeds with high numbers of ceruminous glands?
What factor may contribute to external otitis in breeds with high numbers of ceruminous glands?
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Which disorder is NOT listed as a primary cause of external otitis?
Which disorder is NOT listed as a primary cause of external otitis?
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What predisposing factor is associated with pendulous pinnae in certain breeds?
What predisposing factor is associated with pendulous pinnae in certain breeds?
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Which of the following is a reason why excessive cerumen complicates the treatment of otitis?
Which of the following is a reason why excessive cerumen complicates the treatment of otitis?
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What is a common characteristic of sebaceous adenitis?
What is a common characteristic of sebaceous adenitis?
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Which breed is NOT predisposed to sebaceous adenitis?
Which breed is NOT predisposed to sebaceous adenitis?
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What is the primary treatment for plasma cell pododermatitis?
What is the primary treatment for plasma cell pododermatitis?
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What is the diagnostic procedure for nodular skin disorders?
What is the diagnostic procedure for nodular skin disorders?
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What potential cause is associated with erythema multiforme and toxic epidermal necrolysis?
What potential cause is associated with erythema multiforme and toxic epidermal necrolysis?
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What is the primary function of Glycotech as described in the document?
What is the primary function of Glycotech as described in the document?
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Which components are notably involved in the operation of Glycotech?
Which components are notably involved in the operation of Glycotech?
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In the treatment of small animals, what does the document specify about treatment approaches?
In the treatment of small animals, what does the document specify about treatment approaches?
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Which condition is NOT mentioned as a primary area of concern related to small animals?
Which condition is NOT mentioned as a primary area of concern related to small animals?
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Which of the following options closely relates to the complications expected with otitis media in cats as per the document notes?
Which of the following options closely relates to the complications expected with otitis media in cats as per the document notes?
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What is the primary diagnostic method for confirming uveitis in dogs?
What is the primary diagnostic method for confirming uveitis in dogs?
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Which treatment is most commonly used for dermatomyositis in dogs?
Which treatment is most commonly used for dermatomyositis in dogs?
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What typically characterizes the skin lesions associated with uveitis?
What typically characterizes the skin lesions associated with uveitis?
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Juvenile cellulitis in young dogs is primarily characterized by which of the following symptoms?
Juvenile cellulitis in young dogs is primarily characterized by which of the following symptoms?
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Which of the following complications is specifically associated with CN7 in dogs?
Which of the following complications is specifically associated with CN7 in dogs?
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What is the recommended action regarding breeding for dogs diagnosed with dermatomyositis?
What is the recommended action regarding breeding for dogs diagnosed with dermatomyositis?
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What is the implication of otitis media in animal health?
What is the implication of otitis media in animal health?
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What does the term 'bulla divided ventromedial & dorsolateral' signify?
What does the term 'bulla divided ventromedial & dorsolateral' signify?
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Which condition is commonly referred to as 'puppy strangles'?
Which condition is commonly referred to as 'puppy strangles'?
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What specific symptom is NOT typically associated with juvenile cellulitis?
What specific symptom is NOT typically associated with juvenile cellulitis?
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Which symptom may indicate chronic pathological changes in the ear?
Which symptom may indicate chronic pathological changes in the ear?
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Which of the following is NOT a diagnostic method for uveitis?
Which of the following is NOT a diagnostic method for uveitis?
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What is a potential result of poor healing in veterinary medicine related to ear conditions?
What is a potential result of poor healing in veterinary medicine related to ear conditions?
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What anatomical features are primarily associated with a predisposition to ear canal issues in certain dog breeds?
What anatomical features are primarily associated with a predisposition to ear canal issues in certain dog breeds?
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Which bacterial species is NOT commonly associated with bacterial otitis in animals?
Which bacterial species is NOT commonly associated with bacterial otitis in animals?
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Under which condition should a ceruminolytic cleaner not be used in ear treatment?
Under which condition should a ceruminolytic cleaner not be used in ear treatment?
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Which of the following best describes the nature of ear canal issues in animals?
Which of the following best describes the nature of ear canal issues in animals?
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What is the recommended frequency for applying ear medication in the treatment of ear canal issues?
What is the recommended frequency for applying ear medication in the treatment of ear canal issues?
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What characteristic is commonly used to identify ear mites in animals?
What characteristic is commonly used to identify ear mites in animals?
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Which future complication might arise due to media-related issues affecting the ear?
Which future complication might arise due to media-related issues affecting the ear?
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What is typically the timeframe for observing maximal improvement in clinical signs following treatment with certain medications?
What is typically the timeframe for observing maximal improvement in clinical signs following treatment with certain medications?
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Study Notes
Cytopoint
- Monoclonal antibody targeting IL-31
- Provides 4-8 weeks of relief
- Suitable for dogs of all ages
- Noticeable effect within 24 hours
- Minimal side effects
Adverse Reaction to Food (Food Allergy)
- Mechanism of the disease is not understood
- Typically caused by protein sources in the diet
- Rarely occurs following a change in diet
- Clinical signs:
- Non-seasonal pruritus
- Variable response to corticosteroids
- Lesions secondary to self-trauma
- Secondary yeast and bacterial skin and ear infections are common
- Gastrointestinal signs in some animals
- Can occur in animals of any age including older dogs
Diagnosis of Food Allergy
- Elimination diet trial
- Pruritus reduction of 50% or more
Treatment of Food Allergy
- Remove the irritating substance by bathing or avoiding the irritating substance
Primary Idiopathic Seborrhea
- Hereditary or genetic tendency
- Most common form
- Cocker spaniels, springer spaniels, and West Highland white terriers are predisposed
- Clinical signs:
- Excessive dry or greasy scales
Hepatocutaneous Syndrome
- Cutaneous manifestation of end-stage liver disease
- Associated with glucagonoma in humans
- Clinical signs:
- Older dogs
- Severe crusting of footpads, elbows, and commissures of the mouth
- Systemic illness
Diagnosis of Hepatocutaneous Syndrome
- Signalment and clinical signs
- Histopathology
- Evidence of liver failure
Treatment of Hepatocutaneous Syndrome
- Typically unsuccessful with guarded prognosis
- Correct liver disease if possible
- Nutritional management (intravenous amino acids)
Autoimmune Skin Disorders (General Characteristics)
- Similar manifestations of autoimmunity
- Crusts covering erosions or ulcers are typical lesions
- Common affected areas:
- Nasal planum
- Ear pinnae
- Footpads
- Some diseases may affect the oral cavity or mucous membranes
Diagnosis of Autoimmune Skin Disorders
- Skin biopsy for histopathology
- Additional laboratory tests may be required if systemic signs
Treatment of Autoimmune Skin Disorders
- Immunosuppressive doses of corticosteroids
- Azathioprine (dogs only)
- Chlorambucil (typically used in cats)
- Other immunosuppressive agents (cyclosporine or gold salts)
Pemphigus Complex
- Mechanism: IgG antibodies target adhesion molecules within the epidermis resulting in acantholysis of keratinocytes
- Lesions: pustules, superficial or deep erosions, ulcers
Pemphigus Foliaceus
- Most common autoimmune skin disorder
- Epidermal involvement only
- Common areas: planum, pinnae, footpads, and other body areas
- Characterized by subcorneal to intraepidermal pustules
- Can mimic pyoderma due to pustular nature
Pemphigus Foliaceus (Cats)
- Head most common, also pinna, nasal planum, and periocular
Important Notes
- ↑ liver enzymes
- ↓ albumin
- Glucose
Uveitis
- Acute onset of uveitis
- Hypopigmentation of the skin typically on the face
- Diagnosis:
- Signalment and clinical signs
- Skin biopsy for histopathology
- Histopathology of ocular tissue
- Treatment:
- Treat the uveitis
- Skin lesions are cosmetic
- All melanocytes will be destroyed
Dermatomyositis
- Inherited disorder specific to Collies and Shetland Sheepdogs
- Inflammatory response targeting hair follicles and mastication muscles
- Muscle atrophy and scarring may occur
- Onset usually before one year of age
- Clinical signs: Alopecia, erythema, erosions, ulcers with crusts
- Myopathy may or may not be present
Diagnosis of Dermatomyositis
- Breed and clinical signs
- Histopathology of skin and muscle
Treatment of Dermatomyositis
- Pentoxifylline with or without corticosteroids
- Recommend against breeding
Juvenile Cellulitis
- Commonly referred to as "puppy strangles"
- Immune-mediated condition, exact trigger is not understood
- Often associated with staphylococcal infection
- Clinical signs:
- Pustules, crusts, and cellulitis
- Typically affects the head and neck
- Regional lymphadenopathy
- Pyrexia, lethargy, and depression
Diagnosis of Juvenile Cellulitis
- Signalment and clinical signs
- Rule out other causes of folliculitis
Erythema Multiforme and Toxic Epidermal Necrolysis
- Unknown mechanism, potentially caused by an antigen (drug, toxin, or vaccination)
- Clinical signs:
- Vesicular or ulcerative skin lesions
- Possible systemic illness
- Diagnosis:
- Detailed history and physical exam
- Skin biopsy for histopathology
- Treatment:
- Identify and remove causative agent
- Supportive care
- Immunosuppressive therapy may be needed
Sebaceous Adenitis
- Immune-mediated destruction of sebaceous glands
- Clinical signs:
- Excessive scaling
- Follicular casts
- Patchy alopecia
- Secondary bacterial and yeast infections
- Common
- Non-pruritic
- Breeds predisposed: Standard poodles, Akitas, Samoyeds
- Diagnosis: Histopathology
- Treatment:
- Antiseborrheic therapy
- Topical treatments to restore sebum
Plasma Cell Pododermatitis
- Thought to be immune-mediated, but the mechanism is unknown
- Clinical signs:
- Soft, painless swelling of footpads (in cats)
- Multiple footpads affected
- Diagnosis:
- Detailed history, physical exam
- Histopathology
- Treatment:
- Doxycycline orally (80% response rate)
- Corticosteroids
- Possible spontaneous regression
- Surgery is an option
Nodular Skin Disorders
- Differential diagnosis:
- Infectious causes
- Neoplasia
- Sterile inflammatory causes
- Diagnosis:
- Deep skin biopsy
- Tissue culture (rule out infectious causes)
- Histopathology
- Infectious Causes:
- Bacterial infections
- Fungal infections
- Atypical mycobacterial infections
Treatment of Ear Conditions
- Depends entirely on the diagnosis
Otitis (General Concepts)
- Ear is an extension of the skin
- Conditions affecting the skin can affect the external ear canals
Cerumen
- Debris produced by sebaceous and apocrine glands
- Found in ear canals
- Can trap foreign material complicating treatments
External Otitis
- Inflammation of the external ear canal
- Primary causes:
- Parasites:
- Otodectes cyanotis (ear mites)
- Otobius megnini (spinous ear tick)
- Demodex mites
- Eutrombicula alfreddugesi (chiggers)
- Sarcoptes scabiei
- Poultry mites
- Allergic disorders:
- Most common cause of chronic otitis inflammation in dogs
- Atopy
- Adverse reaction to food
- Contact dermatitis
- Foreign bodies
- Keratinization disorders:
- Primary seborrhea
- Hypothyroidism
- Cancer of the ear canal
- Autoimmune disorders
- Parasites:
Predisposing Causes for External Otitis
- Factors that alter the microenvironment:
- Breeds with increased numbers of ceruminous glands
- Example: Cocker spaniels
- Breeds with stenotic ear canals
- Example: Shar-pei, Chow Chow
- Pendulous pinnae may restrict access to the ear canal
- Breeds with increased numbers of ceruminous glands
- Excessive moisture
- Frequent swimming
Neoplasia
- Cancer of the ear canal
Sterile Diseases
- Sterile granuloma
- Sterile nodular panniculitis
Glycotech
- Uses monosaccharides and amikyls
- Polyglycosides
- Used for Pseudomonas bacteria
- Remember*: This summary was generated by an AI, and it is based on the provided text. While the AI has attempted to capture the key information, it is advised to consult reliable veterinary resources and a professional for complete and accurate information.
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Description
Test your knowledge on the treatment and diagnosis of allergies and skin conditions in dogs, including food allergies and primary idiopathic seborrhea. This quiz covers therapies like Cytopoint and effective dietary management strategies. Learn about the symptoms, diagnosis methods, and specific breeds prone to skin issues.