Endosomes and Lysosomes I, II

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

Which organelle is responsible for the digestion of materials in the cell?

  • Endoplasmic reticulum
  • Golgi apparatus
  • Mitochondria
  • Lysosome (correct)

What is the pH of lysosomes?

  • pH ~ 9.0
  • pH ~ 7.0
  • pH ~ 5.0 (correct)
  • pH ~ 3.0

Which process involves the self-digestion of organelles and proteins by the cell?

  • Phagocytosis
  • Pinocytosis
  • Autophagy (correct)
  • Receptor-mediated endocytosis

What is the main cause of lysosomal storage diseases?

<p>Deficiency in a lysosomal enzyme (C)</p> Signup and view all the answers

Which enzyme is defective in Tay-Sachs Disease?

<p>a-Hexosaminidase A (C)</p> Signup and view all the answers

Which disease is characterized by the accumulation of Glucocerebroside in macrophages?

<p>Gaucher's Disease (B)</p> Signup and view all the answers

Which disease is associated with the accumulation of Glycosphingolipids in the vascular endothelium of multiple organ systems?

<p>Fabry Disease (B)</p> Signup and view all the answers

What is the pH of the lumen in the late endosome?

<p>5.5 (C)</p> Signup and view all the answers

What is the primary function of multivesicular bodies (MVBs)?

<p>Sorting and degradation of integral membrane proteins (C)</p> Signup and view all the answers

Which of the following is NOT one of the main routes for delivery of digestible materials to lysosomes?

<p>Exocytosis (A)</p> Signup and view all the answers

Which mechanism of endocytosis involves ingestion of bacteria, large particles, or other cells?

<p>Phagocytosis (B)</p> Signup and view all the answers

What is the function of clathrin in the formation of clathrin-coated vesicles?

<p>Captures membrane receptors and bound molecules (B)</p> Signup and view all the answers

What is the GTPase required for the budding of clathrin-coated vesicles?

<p>Dynamin (B)</p> Signup and view all the answers

Which of the following is NOT a mechanism of endocytosis?

<p>Exocytosis (B)</p> Signup and view all the answers

Which of the following is NOT one of the main steps involved in phagocytosis?

<p>Formation of Lysosomes (C)</p> Signup and view all the answers

Which of the following is NOT a role of clathrin, AP2, and dynamin in receptor-mediated endocytosis?

<p>Fusion of Vesicles with Lysosomes (C)</p> Signup and view all the answers

Which organelle is responsible for the digestion of materials in the cell?

<p>Lysosome (C)</p> Signup and view all the answers

What is the pH of lysosomes?

<p>pH ~ 5.0 (B)</p> Signup and view all the answers

Which disease is associated with the accumulation of Glycosphingolipids in the vascular endothelium of multiple organ systems?

<p>Tay-Sachs Disease (D)</p> Signup and view all the answers

Which enzyme is defective in Tay-Sachs Disease?

<p>Hexosaminidase A (B)</p> Signup and view all the answers

Which process involves the self-digestion of organelles and proteins by the cell?

<p>Autophagy (C)</p> Signup and view all the answers

What is the primary function of multivesicular bodies (MVBs)?

<p>Recycling of endosomal membrane (C)</p> Signup and view all the answers

Which of the following is NOT one of the main routes for delivery of digestible materials to lysosomes?

<p>Exocytosis (B)</p> Signup and view all the answers

What is the primary function of multivesicular bodies (MVBs)?

<p>Sorting and recycling of receptors (C)</p> Signup and view all the answers

What is the pH of the lumen in the late endosome?

<p>Slightly acidic (pH 5-6) (B)</p> Signup and view all the answers

What is the GTPase required for the budding of clathrin-coated vesicles?

<p>Dynamin (D)</p> Signup and view all the answers

What is the function of clathrin in the formation of clathrin-coated vesicles?

<p>Captures membrane receptors and bound molecules (D)</p> Signup and view all the answers

Which mechanism of endocytosis involves ingestion of bacteria, large particles, or other cells?

<p>Phagocytosis (A)</p> Signup and view all the answers

Which enzyme is defective in Pompe Disease?

<p>a-D-Glucosidase (C)</p> Signup and view all the answers

Which disease is associated with the accumulation of GM2 Gangliosides in the brain?

<p>Tay-Sachs Disease (A)</p> Signup and view all the answers

Which disease is characterized by the accumulation of Glucocerebroside in macrophages?

<p>Gaucher's Disease (A)</p> Signup and view all the answers

Which disease is associated with the accumulation of Glycosphingolipids in the vascular endothelium of multiple organ systems?

<p>Fabry Disease (A)</p> Signup and view all the answers

Which disease is characterized by the accumulation of Sphingomyelin and impairs formation of lipid rafts in association with cholesterol?

<p>Niemann-Pick Disease (C)</p> Signup and view all the answers

Which enzyme is defective in I-Cell Disease?

<p>a-D-Glucosidase (D)</p> Signup and view all the answers

Which disease is associated with the accumulation of Glycosphingolipids in the vascular endothelium of multiple organ systems?

<p>Gaucher Disease (B)</p> Signup and view all the answers

Which of the following is NOT a role of clathrin, AP2, and dynamin in receptor-mediated endocytosis?

<p>Sorting of hydrolytic enzymes (B)</p> Signup and view all the answers

What is the primary function of multivesicular bodies (MVBs)?

<p>Sorting and degradation of integral membrane proteins (D)</p> Signup and view all the answers

What is the main cause of lysosomal storage diseases?

<p>Deficiency of acid hydrolases (A)</p> Signup and view all the answers

Which of the following is NOT one of the main steps involved in phagocytosis?

<p>Formation of a phagosome (B)</p> Signup and view all the answers

Which of the following is NOT a function of dynamin in receptor-mediated endocytosis?

<p>Binding of the ligand to the receptor (A)</p> Signup and view all the answers

Which of the following is NOT a specialization in lysosomal membranes?

<p>Clathrin (A)</p> Signup and view all the answers

Which of the following is the main type of ligand involved in receptor-mediated endocytosis?

<p>Proteins (C)</p> Signup and view all the answers

Which of the following is NOT a role of clathrin in receptor-mediated endocytosis?

<p>Binding of the ligand to the receptor (C)</p> Signup and view all the answers

Which of the following is the main function of multivesicular bodies (MVBs)?

<p>Recycling of membrane proteins (B)</p> Signup and view all the answers

Flashcards are hidden until you start studying

Related Documents

More Like This

Use Quizgecko on...
Browser
Browser