Verapamil Flashcards
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Questions and Answers

What is the brand name of Verapamil?

  • Lisinopril
  • Calan (correct)
  • Isoptin SR (correct)
  • Amlodipine
  • What is the generic name for Verapamil?

    Verapamil

    What therapeutic classifications does Verapamil belong to? (Select all that apply)

  • Antianginals (correct)
  • Antiarhythmics (correct)
  • Antidiabetics
  • Antihypertensives (correct)
  • What is the pharmacologic classification of Verapamil?

    <p>Calcium channel blockers</p> Signup and view all the answers

    What is the action of Verapamil?

    <p>Inhibits the transport of calcium in myocardial and vascular smooth muscle cells.</p> Signup and view all the answers

    What are the therapeutic effects of Verapamil?

    <p>Systemic vasodilation, decreased BP, coronary vasodilation.</p> Signup and view all the answers

    Adverse reactions to Verapamil include CHF and severe hypotension.

    <p>True</p> Signup and view all the answers

    What is the usual route and dosage of Verapamil?

    <p>120 mg, by mouth once daily.</p> Signup and view all the answers

    Caution is advised when prescribing Verapamil to elderly patients.

    <p>True</p> Signup and view all the answers

    What interactions should be monitored when taking Verapamil?

    <p>Additive hypotension with antihypertensives, decreased effectiveness with NSAIDs.</p> Signup and view all the answers

    What key implementations should be followed when administering Verapamil?

    <p>Monitor BP and pulse, assess for signs of heart failure.</p> Signup and view all the answers

    Study Notes

    Brand Name

    • Calan, Calan SR, Isoptin SR, Verelan, Verelan PM are the various brand names for Verapamil.

    Generic Name

    • The generic name for these medications is Verapamil.

    Therapeutic Classification

    • Primarily classified as antianginals, antiarrhythmics, antihypertensives, and vascular headache suppressants.

    Pharmacologic Classification

    • Functions as a calcium channel blocker, affecting calcium transport in muscle cells.

    Mechanism of Action

    • Inhibits calcium transport in myocardial and vascular smooth muscle cells.
    • Results in decreased excitation-contraction coupling and overall contraction.
    • Reduces conduction through the SA and AV nodes, lengthening the refractory period in conduction tissue.

    Therapeutic Effects

    • Promotes systemic vasodilation, leading to decreased blood pressure (BP).
    • Induces coronary vasodilation, reducing the frequency and severity of angina attacks.
    • Lowers ventricular rate in cases of atrial fibrillation or flutter.

    Adverse Reactions/Side Effects

    • Potentially causes congestive heart failure (CHF), severe hypotension, AV block, severe bradycardia, hepatotoxicity.
    • Other side effects may include dizziness, edema, and fatigue.

    Route and Dosage

    • Administered as a 120 mg tablet by mouth, typically once daily.

    Contradictions

    • Use with caution in patients with gastroesophageal reflux disease (GERD) and the elderly population.

    Interactions

    • May cause additive hypotension when used with other antihypertensives.
    • Effectiveness can be decreased by the concurrent use of NSAIDs.
    • Co-administration with IV beta blockers should be approached with caution.
    • Grapefruit juice can increase serum levels and effects of Verapamil.

    Implementation

    • Monitor blood pressure and pulse prior to beginning therapy.
    • Assess elderly patients for fall risks and monitor intake and output, along with daily weights.
    • Look for signs of heart failure, and report any palpitations, edema, or weight gain.
    • Tablets should not be crushed or chewed.
    • Avoid alcohol and grapefruit juice while on medication.
    • Patients also taking digoxin should have serum levels checked regularly and observed for signs of toxicity.
    • Regular monitoring of potassium levels is essential.
    • Administer with meals or milk to reduce gastric irritation.

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    Description

    Test your knowledge with these flashcards on Verapamil, including its brand and generic names, therapeutic classifications, pharmacologic details, and action mechanisms. Perfect for students and professionals in the pharmaceutical field.

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