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L4 Ventilation Perfusion Matching and Dead Space in Medical Physiology

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What is the definition of anatomical dead space?

Volume of air in the conducting zone where gas exchange does not occur

Which type of dead space is a combination of anatomical and alveolar dead space?

Physiological dead space

What effect does sympathetic stimulation have on dead space?

Increases dead space volume

What is the relationship between anatomical and physiological dead space under normal conditions?

Anatomical dead space is equivalent to physiological dead space

Which factor leads to a decrease in the volume of dead space?

Parasympathetic stimulation

What does physiological dead space encompass?

Anatomical dead space and alveolar dead space combined

What is the main function of the upper respiratory tract?

To filter and warm the inspired air

What is the difference between pulmonary ventilation and alveolar ventilation?

Pulmonary ventilation is the volume of air breathed in and out per minute, while alveolar ventilation is the volume of air reaching the alveoli per minute

Which factor affects alveolar ventilation the most?

Dead space volume

In the case of shallow rapid breathing, what happens to pulmonary ventilation and alveolar ventilation?

Pulmonary ventilation remains normal while alveolar ventilation decreases

What is the primary purpose of alveolar ventilation?

To facilitate gas exchange in the lungs

What is the formula for calculating alveolar ventilation?

Tidal volume - Dead space x Respiratory rate

What is the relationship between perfusion and V̇/Q̇ ratio at the base of the lungs?

Perfusion is higher, and V̇/Q̇ ratio is lower

Which type of dead space is defined by the sum of anatomical and alveolar dead spaces?

Total dead space

How do ventilation and V̇/Q̇ ratio change from apex to base of the lungs?

Ventilation is higher at the base, V̇/Q̇ ratio is lower at the apex

What is the consequence of impaired perfusion on the V/Q matching in the lungs?

Increased V/Q mismatching

Differentiate between physiological and anatomical dead space.

Physiological dead space includes conducting airways

In case of impaired ventilation, what happens to the V/Q matching in the lungs?

Increased V/Q mismatching

In the standing position, which zone of the lung experiences no blood flow?

Zone 1

In which zone does blood flow occur only during systolic blood pressure?

Zone 2

Which zone experiences continuous blood flow throughout the cardiac cycle?

Zone 3

Which condition can lead to the appearance of Zone 1 in the lungs?

All of the above

If the alveolar ventilation (VA) is 4 L/min and the cardiac output (Q) is 5 L/min, what is the ventilation-perfusion ratio (VA/Q)?

0.8

In the standing position, where is the ventilation-perfusion ratio (VA/Q) higher?

At the apex of the lung

In which scenario would the ventilation/perfusion (VA/Q) ratio be the highest?

Partial mucus plugging of a bronchiole

What condition is most likely to cause a low ventilation/perfusion (V̇/Q̇) ratio?

Severe right heart failure

Which of the following lung conditions is likely to result in decreased gas exchange due to high ventilation and a V̇/Q̇ ratio greater than average?

Destruction of pulmonary capillaries by emphysema

A scenario with severe left heart failure is most likely to result in which of the following pulmonary abnormalities?

High V̇/Q̇ ratio

Which condition would cause a V/Q ratio closest to 1, representing almost perfect matching of ventilation and perfusion?

Pulmonary embolus

What impact does emphysema have on the ventilation/perfusion (V̇/Q̇) ratio?

Increases both ventilation and perfusion

Test your knowledge on ventilation perfusion matching and dead space in medical physiology with this quiz. Learn about dead space types, physiological vs anatomical dead space, pulmonary and alveolar ventilation, V/Q ratio, and regional variation in the lungs.

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