Podcast
Questions and Answers
DNA gives the genetic information for making proteins to mRNA by adding _________ bases.
DNA gives the genetic information for making proteins to mRNA by adding _________ bases.
complementary
Ribosomes read the code on the mRNA to make proteins one amino acid at a time.
Ribosomes read the code on the mRNA to make proteins one amino acid at a time.
True (A)
The code for adding one amino acid is actually a group of 3 nitrogenous bases on the mRNA. This is called a _________.
The code for adding one amino acid is actually a group of 3 nitrogenous bases on the mRNA. This is called a _________.
codon
How many codons code for one amino acid?
How many codons code for one amino acid?
Each codon has an _________, a group of 3 nitrogen bases that will match with a codon on the mRNA.
Each codon has an _________, a group of 3 nitrogen bases that will match with a codon on the mRNA.
Which codon does the ribosome begin making proteins and adding amino acids when it reads?
Which codon does the ribosome begin making proteins and adding amino acids when it reads?
What type of codon does the ribosome reach to stop adding more amino acids?
What type of codon does the ribosome reach to stop adding more amino acids?
Name the scientists who identified and published the structure of DNA in the 1950s.
Name the scientists who identified and published the structure of DNA in the 1950s.
Rosalind Franklin's work "assisted" the discovery of the structure of DNA. Her work included Photo______.
Rosalind Franklin's work "assisted" the discovery of the structure of DNA. Her work included Photo______.
The structure of DNA is known as a ______ ______ (twisted ladder).
The structure of DNA is known as a ______ ______ (twisted ladder).
The sides of the DNA ladder are made of _________ and sugars (deoxyribose).
The sides of the DNA ladder are made of _________ and sugars (deoxyribose).
The rungs of the DNA ladder are made of ________ _________.
The rungs of the DNA ladder are made of ________ _________.
Why does DNA need to replicate?
Why does DNA need to replicate?
What is the first step of DNA replication?
What is the first step of DNA replication?
During DNA replication, what type of bonds bond with the open strands of DNA?
During DNA replication, what type of bonds bond with the open strands of DNA?
During DNA replication, two new different strands of DNA have been made.
During DNA replication, two new different strands of DNA have been made.
Adenine always pairs with Thymine.
Adenine always pairs with Thymine.
Guanine pairs with Cytosine.
Guanine pairs with Cytosine.
What type of bond holds the two nitrogenous bases together?
What type of bond holds the two nitrogenous bases together?
What makes us all so different if there are only 4 bases that pair together in certain ways?
What makes us all so different if there are only 4 bases that pair together in certain ways?
Match the components that make up of a nucleotide:
Match the components that make up of a nucleotide:
Mutations often result in a change in the sequence of what acid?
Mutations often result in a change in the sequence of what acid?
Mutations can ONLY be harmful.
Mutations can ONLY be harmful.
When do mutations often occur?
When do mutations often occur?
Mutations in DNA can lead to a change in amino acid which can ultimately change the ________.
Mutations in DNA can lead to a change in amino acid which can ultimately change the ________.
During what process does a substitution mutation occur with the wrong nucleotide base?
During what process does a substitution mutation occur with the wrong nucleotide base?
Substitution mutations are less harmful than other mutations.
Substitution mutations are less harmful than other mutations.
A deletion mutation happens when one or more _________ are deleted from a DNA sequence.
A deletion mutation happens when one or more _________ are deleted from a DNA sequence.
A deletion mutation can be any # of _________, from one to an entire piece of a chromosome.
A deletion mutation can be any # of _________, from one to an entire piece of a chromosome.
An insertion mutation happens when one or more ________ are inserted into a DNA sequence.
An insertion mutation happens when one or more ________ are inserted into a DNA sequence.
An insertion mutation can be a single _________ or multiple, from one to an entire piece of a chromosome.
An insertion mutation can be a single _________ or multiple, from one to an entire piece of a chromosome.
Point mutations are mutations that only change a single _________.
Point mutations are mutations that only change a single _________.
Insertions and Deletions are known as a Point Mutation because they can end up shifting/changing the other nucleotides and therefore the codons.
Insertions and Deletions are known as a Point Mutation because they can end up shifting/changing the other nucleotides and therefore the codons.
Mutations in gametes (sperm and egg cells) will be passed onto offspring.
Mutations in gametes (sperm and egg cells) will be passed onto offspring.
Mutations in what type of cells will not be passed onto offspring?
Mutations in what type of cells will not be passed onto offspring?
In Transcription, what polymerase copies DNA?
In Transcription, what polymerase copies DNA?
What is made in Transcription?
What is made in Transcription?
MRNA is double stranded.
MRNA is double stranded.
Where does Translation occur?
Where does Translation occur?
What gives direction to the tRNA during Translation?
What gives direction to the tRNA during Translation?
TRNA brings the incorrect amino acids during Translation.
TRNA brings the incorrect amino acids during Translation.
If a mutation occurs in a somatic cell, which of the following is most likely to happen?
If a mutation occurs in a somatic cell, which of the following is most likely to happen?
A deletion mutation involves the insertion of one or more bases into a DNA sequence.
A deletion mutation involves the insertion of one or more bases into a DNA sequence.
Describe how a mutation in the DNA sequence can ultimately lead to a change in the protein that it codes for.
Describe how a mutation in the DNA sequence can ultimately lead to a change in the protein that it codes for.
During DNA replication, the two strands of DNA are unzipped or separated, and the weak ________ bonds are split.
During DNA replication, the two strands of DNA are unzipped or separated, and the weak ________ bonds are split.
Match the following types of RNA with their functions:
Match the following types of RNA with their functions:
Flashcards
How is genetic information passed to mRNA?
How is genetic information passed to mRNA?
DNA gives the genetic information for making proteins to mRNA by adding complementary bases.
Codon
Codon
The code for adding one amino acid is a group of 3 nitrogenous bases on the mRNA.
What does one codon code for?
What does one codon code for?
Each codon codes for one amino acid.
Anticodon
Anticodon
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Universal Start Codon
Universal Start Codon
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Stop Codon
Stop Codon
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When was DNA first found?
When was DNA first found?
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Watson & Crick
Watson & Crick
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Rosalind Franklin
Rosalind Franklin
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DNA Structure
DNA Structure
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DNA ladder components
DNA ladder components
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What are the rungs of the DNA ladder made of?
What are the rungs of the DNA ladder made of?
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Why does DNA replicate?
Why does DNA replicate?
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First step of DNA replication
First step of DNA replication
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Second step of DNA replication
Second step of DNA replication
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Result of DNA replication
Result of DNA replication
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Adenine pairs with...
Adenine pairs with...
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Guanine pairs with...
Guanine pairs with...
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DNA bonds
DNA bonds
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Parts of a Nucleotide
Parts of a Nucleotide
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What is a mutation?
What is a mutation?
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When do mutations occur?
When do mutations occur?
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What is the result of a change in DNA?
What is the result of a change in DNA?
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Substitution mutation
Substitution mutation
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Deletion
Deletion
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Insertion
Insertion
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Point Mutations
Point Mutations
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Somatic Mutation
Somatic Mutation
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What is Cancer?
What is Cancer?
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Abnormal Cell Division
Abnormal Cell Division
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A gene has...
A gene has...
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How do tumors grow?
How do tumors grow?
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Tumors definition
Tumors definition
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Difference beetween tumors
Difference beetween tumors
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Cancer cells spread...
Cancer cells spread...
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Substances that cause Cancer...
Substances that cause Cancer...
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Transcription: What?
Transcription: What?
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Transcription outcome
Transcription outcome
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Transcription What
Transcription What
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Translation
Translation
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tRNA function
tRNA function
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tRNA in translation
tRNA in translation
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DNA instructions transferred to mRNA
DNA instructions transferred to mRNA
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RNA unique factor
RNA unique factor
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mRNA function
mRNA function
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How are proteins built?
How are proteins built?
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Role of tRNA
Role of tRNA
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RNA name
RNA name
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Message carrier
Message carrier
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Differences of RNA and DNA
Differences of RNA and DNA
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Name of messenger
Name of messenger
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Transportation
Transportation
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The building base
The building base
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Study Notes
Definition of a Vector Space
- A vector space over a field $\mathbb{K}$ is a set $E$ with two operations: vector addition ($E \times E \rightarrow E$) and scalar multiplication ($\mathbb{K} \times E \rightarrow E$).
- Vector addition is associative: $\forall u, v, w \in E, (u + v) + w = u + (v + w)$.
- Vector addition is commutative: $\forall u, v \in E, u + v = v + u$.
- There exists an additive identity element $0_E \in E$ such that $\forall u \in E, u + 0_E = u$.
- For each $u \in E$, there exists an additive inverse $-u \in E$ such that $u + (-u) = 0_E$.
- Scalar multiplication is distributive over vector addition: $\forall \lambda \in \mathbb{K}, \forall u, v \in E, \lambda(u + v) = \lambda u + \lambda v$.
- Scalar multiplication is distributive over field addition: $\forall \lambda, \mu \in \mathbb{K}, \forall u \in E, (\lambda + \mu)u = \lambda u + \mu u$.
- Scalar multiplication is associative: $\forall \lambda, \mu \in \mathbb{K}, \forall u \in E, \lambda(\mu u) = (\lambda \mu)u$.
- There exists a multiplicative identity element $1_{\mathbb{K}}$ such that $\forall u \in E, 1_{\mathbb{K}} u = u$.
Examples of Vector Spaces
- $\mathbb{K}^n$ is the set of n-tuples with elements from $\mathbb{K}$.
- $\mathcal{M}_{m,n}(\mathbb{K})$ is the set of $m \times n$ matrices with coefficients in $\mathbb{K}$.
- $\mathbb{K}[X]$ is the set of polynomials with coefficients in $\mathbb{K}$.
- $\mathcal{F}(X, \mathbb{K})$ is the set of functions from $X$ to $\mathbb{K}$.
Subspaces
- A subset $F$ of vector space $E$ is a subspace if it's non-empty, closed under vector addition, and closed under scalar multiplication.
- $F$ is a subspace if $0_E \in F$ and $\forall u, v \in F, \forall \lambda \in \mathbb{K}, \lambda u + v \in F$.
Linear Combinations
- A linear combination of vectors $u_1, u_2,..., u_n$ in $E$ is a vector of the form $\lambda_1 u_1 + \lambda_2 u_2 +... + \lambda_n u_n$, where $\lambda_i \in \mathbb{K}$.
Linear Span (or Vector Space Generated)
- Denoted as $\text{Vect}(S)$ for $S \subseteq E$, it's the set of all possible linear combinations of vectors from $S$.
- Is the smallest subspace of $E$ containing $S$.
Linear Independence, Spanning Sets, and Bases
- A family of vectors $(u_1, u_2,..., u_n)$ is linearly independent if $\lambda_1 u_1 + \lambda_2 u_2 +... + \lambda_n u_n = 0_E \Rightarrow \lambda_1 = \lambda_2 =... = \lambda_n = 0$.
- A family of vectors $(u_1, u_2,..., u_n)$ spans $E$ if $E = \text{Vect}(u_1, u_2,..., u_n)$.
- A family of vectors $(u_1, u_2,..., u_n)$ is a basis of $E$ if it is both linearly independent and spans $E$.
Dimension of a Vector Space
- If $E$ has a finite basis, all bases of $E$ have the same number of elements.
- This number is the dimension of $E$, denoted as $\dim(E)$.
Sum of Subspaces
- If $F$ and $G$ are subspaces of $E$, their sum is $F + G = {u + v \mid u \in F, v \in G}$.
- $F + G$ is a subspace of $E$.
Direct Sum
- The sum $F + G$ is called a direct sum, denoted $F \oplus G$, if every vector in $F + G$ can be uniquely written as the sum of a vector from $F$ and a vector from $G$.
- $F + G$ is a direct sum if and only if $F \cap G = {0_E}$.
- If $F \oplus G = E$, then $F$ and $G$ are supplementary in $E$.
Rank Theorem
- For a linear map $f : E \rightarrow F$ between finite-dimensional vector spaces, $\dim(E) = \dim(\text{Ker}(f)) + \dim(\text{Im}(f))$, where $\text{Ker}(f)$ is the kernel and $\text{Im}(f)$ is the image of $f$.
NetApp ONTAP CLI
Introduction
- This quick start guide provides an introduction to the NetApp ONTAP Command Line Interface (CLI). The CLI is a powerful tool to manage and configure storage systems.
Prerequisites
- A running NetApp storage system is required.
- Network access to the system.
- An SSH client installed on the computer.
- Basic storage concepts knowledge is a must
Accessing the ONTAP CLI
- Use an SSH client to connect to the IP address of the storage system.
- Open the SSH client, input the IP address of your system as the "Hostname". Ensure "Connection type" is "SSH" and click "Open". Enter username and password when prompted.
Basic commands
help
: Displays available commands.man
: Shows the manual page for a specified command.version
: Displays the ONTAP version running.date
: Shows current system date and time.uptime
: Displays how long the system has been running.system status show
: Displays basic system status information.
Navigating the CLI
- The CLI is organized in a command hierarchy. Use
cd
to navigate. For example,cd /
changes to the top level of the hierarchy. - The
help
command lists available commands at the current level.
Getting Help
- Use
man
for help with specific commands; for example:man volume create
. It shows detailed information including syntax, options, and examples..
Using Scripts with the CLI
- The CLI can automate storage management tasks by creating and running scripts containing a series of commands.
- Run scripts with the
cli -f
command, where `` is the script filename.
Photoelectric Effect
- Electrons emit from a metal surface when irradiated by light.
- Minimum energy $W$ (work function) is required to release electrons.
- Maximum kinetic energy of photoelectrons: $E_{kin} = h\nu - W = h\frac{c}{\lambda} - W$, where $\nu$ is frequency and $\lambda$ is wavelength.
Experimental data
- Experimental data are provided for three metals with cutoff wavelengths:
- Sodium: $\lambda_{cutoff} = 680 nm$
- Potassium: $\lambda_{cutoff} = 560 nm$
- Cesium: $\lambda_{cutoff} = 650 nm$
Tasks
- Calculate work functions for each metal in electron volts (eV), given that $1 eV = 1.602 * 10^{-19} J$.
- Describe how the kinetic energy of the photoelectrons changes when light intensity is doubled or when the light's wavelength is halved.
Compton Effect
- A photon transfers energy to a particle during scattering.
- Determine the increase in a photon's wavelength by a factor of ten after scattering, given initial wavelengths of:
- a) $1 \mu m$
- b) $500 nm$
Bohr Model of the Hydrogen Atom
- An electron orbits an atomic nucleus (electron and proton) in a circular path, with quantized angular momentum $L = n\hbar, n \in \mathbb{N}$.
- Coulomb force and centripetal force determine the electron's radius.
Tasks
- Determine an expression for the radius $r_n$ in terms of velocity $v_n$ using the Coulomb force and centripetal force.
- Determine an expression for velocity $v_n$ in terms of $n$ using the Bohr postulate (quantization of angular momentum).
- Determine $r_n$ as a function of $n$, and calculate the Bohr radius $a_0$ for $n = 1$.
Uncertainty Principle
- Use the uncertainty principle to demonstrate that electrons cannot exist within the atomic nucleus.
- The diameter of an atomic nucleus is approximately $10^{-14}m$.
Tasks
- Calculate the minimum momentum of electrons if they were located within the nucleus.
- Calculate the associated velocity and kinetic energy and interpret the result.
- The rest energy of an electron is given as $0.51 MeV = 8.187 * 10^{-14} J$.
Einstein Field Equation Review
- Covariant derivatives of tensors transform as tensors and are used to define the curvature tensor $R^{\mu}_{\nu \rho \sigma}$.
The Einstein Field Equation
- A relativistic generalization of Poisson's equation is needed to describe how matter curves spacetime: $G_{\mu\nu} = \kappa T_{\mu\nu}$.
Conditions on $G_{\mu\nu}$
- It must be a tensor.
- It must depend only on the metric and its first and second derivatives.
- It must be symmetric.
- It must be conserved, following $\nabla_{\mu} G^{\mu\nu} = 0$.
General Tensor Formula
- The most general tensor meeting conditions 1 and 2 is $G_{\mu\nu} = c_1 R_{\mu\nu} + c_2 R g_{\mu\nu} + c_3 \Lambda g_{\mu\nu}$.
- $R_{\mu\nu} \equiv R^{\alpha}{\mu \alpha \nu}$ is the Ricci tensor, $R \equiv R^{\mu}{\mu}$ is the Ricci scalar, $\Lambda$ is the cosmological constant, and $c_i$'s are constants.
Applying the Bianchi Identity
- Contracting the Bianchi identity $\nabla_{\lambda} R_{\mu\nu\rho\sigma} + \nabla_{\rho} R_{\mu\nu\sigma\lambda} + \nabla_{\sigma} R_{\mu\nu\lambda\rho} = 0$ gives $\nabla_{\mu} R^{\mu\nu} = \frac{1}{2} \nabla^{\nu} R$.
Einstein's Choice
- Einstein's equation sets $c_1 = 1$ and enforces the conservation condition, resulting in $G_{\mu\nu} = R_{\mu\nu} - \frac{1}{2} R g_{\mu\nu} + \Lambda g_{\mu\nu}$.
- This gives the Einstein field equation: $R_{\mu\nu} - \frac{1}{2} R g_{\mu\nu} + \Lambda g_{\mu\nu} = \kappa T_{\mu\nu}$.
Definition of the Natural Logarithm
- The natural logarithm function, $ln$, is defined on $]0; +\infty[$ as the primitive of $x \longmapsto \frac{1}{x}$ that equals zero at $x=1$.
- Key Values: $ln(1) = 0$, $ln(e) = 1$.
- Inverse Relationships: For $x > 0$, $e^{ln(x)} = x$, and for all real x, $ln(e^x) = x$.
Algebraic Properties
- Logarithm of Product: $ln(ab) = ln(a) + ln(b)$
- Logarithm of Reciprocal: $ln(\frac{1}{a}) = -ln(a)$
- Logarithm of Quotient: $ln(\frac{a}{b}) = ln(a) - ln(b)$
- Logarithm of Power: $ln(a^n) = n \cdot ln(a)$
- Logarithm of Square Root: $ln(\sqrt{a}) = \frac{1}{2} ln(a)$
Properties of the Natural Logarithm
- $x$ approaches 0, $ln(x)$ approaches negative infinitiy
- $x$ apporaches the positive infinity, $ln(x)$ approaches to the positive infinity
- $x$ apporaches the positive infinity, a quotient $ln(x)/x$ appoaches 0
- $x$ approaches 0, a multiple $x ln(x)$ approaches 0
Derivative of $ln(x)$
- The derivative of $ln(x)$ is given by $(ln(x))' = \frac{1}{x}$.
Variations
- The function $ln$ is strictly increasing on $]0; +\infty[$.
Representational curve
- Function starts from negative infinity, increasing infinitely and crosses x-axis @ (1,0)
Angular Momentum Definition
- Angular momentum of a particle with respect to a fixed point: $\vec{L} = \vec{r} \times \vec{p} = \vec{r} \times (m\vec{v})$.
- $\vec{L}$ is angular momentum, $\vec{r}$ is the position vector, $\vec{p}$ the linear momentum with $m$ as mass and $\vec{v}$ as velocity.
Rotation around a Fixed Axis
- Angular momentum of a rigid body rotating around fixed axis: $L = I\omega$, where $I$ is the moment of inertia and $\omega$ the angular velocity.
Torque and Angular Momentum
- The rate of change of angular momentum equals the applied torque: $\tau = \frac{d\vec{L}}{dt}$.
- $\tau$ being torque
Conservation of Angular Momentum
- If the external torque is zero, the total angular momentum of the system is conserved: $\vec{L} = \text{constant}$.
Angular and Linear variable similarities
- Position: $x = r\theta$
- Velocity: $v = r\omega$
- Acceleration: $a = r\alpha$
- Magnitude : $\tau = rF$
- Momentum: $L = I\omega = r\cdot p$
DTFT From Fourier Series
- Begin with Fourier series analysis formula: $a_k = \frac{1}{T} \int_{} x(t)e^{-jk\Omega t} dt$, with $\Omega = \frac{2\pi}{T}$.
Approximating $x(t)$
- Sample $x(t)$ using Dirac delta function, representing using $\hat{x}(t)$ $$x[n] = x[nT]$$ $$ \hat{x}(t) = \sum_{n=-\infty}^{\infty} x[n] \delta(t - nT) $$
Deriving DTFT
- Fourier Transform of $\hat{x}(t)$: $$ X(e^{j\omega}) = \sum_{n=-\infty}^{\infty} x[n] e^{-j\omega n} $$
Inverse DTFT
- The inverse Discrete-Time Fourier Transform (DTFT) is: $$ x[n] = \frac{1}{2\pi} \int_{} X(e^{j\omega}) e^{j\omega n} d\omega $$
Property of the Functions
- DTFT is periodic with period $2\pi$
- DTFT has Continuous frequency on the range $[-\pi, \pi]$
Bernoulli's Principle
- Increase in fluid speed occurs with decrease in pressure or potential energy.
Airplane Flight Application
- Air flows faster over the wing, decreasing pressure and creating lift.
Airfoil Definition
- It is a structure with curved surfaces designed to provide lift when air flows around it
Lift
- It is generated with more pressire @ bottom of wing vs top
Bernoulli's Equation
$$P_1 + \frac{1}{2} \rho v_1^2 + \rho g h_1 = P_2 + \frac{1}{2} \rho v_2^2 + \rho g h_2$$
Simplified
$$P_1 + \frac{1}{2} \rho v_1^2 = P_2 + \frac{1}{2} \rho v_2^2$$
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Description
Explore the definition of a vector space over a field, covering vector addition and scalar multiplication properties. Key axioms include associativity, commutativity, and the existence of additive identity and inverse elements. Understand the distributive and associative nature of scalar multiplication.