Prostitis

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Questions and Answers

A patient presents with a history of recent BCG therapy for bladder cancer and now exhibits signs of prostatitis. Which type of prostatitis is most likely affecting this patient?

  • Acute bacterial prostatitis
  • Acute prostatitis
  • Granulomatous prostatitis (correct)
  • Chronic abacterial prostatitis

Which of the following bacterial species are most frequently associated with infectious cases of prostatitis?

  • Klebsiella pneumoniae and Proteus mirabilis
  • Streptococcus pneumoniae and Haemophilus influenzae
  • Escherichia coli and Enterococcus species (correct)
  • Staphylococcus aureus and Pseudomonas aeruginosa

In distinguishing between acute and chronic prostatitis based on histological findings, which cellular infiltrate is most indicative of acute prostatitis?

  • Diffuse lymphocytic infiltrate
  • Predominance of plasma cells
  • Abundance of neutrophils (correct)
  • Presence of granulomatous inflammation

A patient is suspected of having prostatitis. Which clinical presentation would suggest a diagnosis of bacterial prostatitis rather than abacterial prostatitis?

<p>Elevated white blood cell count in expressed prostatic secretions (D)</p> Signup and view all the answers

A patient presents with symptoms suggestive of prostatitis, but initial cultures are negative. What is the most likely diagnosis?

<p>Chronic abacterial prostatitis (C)</p> Signup and view all the answers

What histological feature is most characteristic of granulomatous prostatitis when viewed under a microscope?

<p>Formation of granulomas with giant cells and plasma cells. (C)</p> Signup and view all the answers

Following BCG therapy for bladder cancer, a patient develops granulomatous prostatitis. Which immunological process is primarily responsible for the development of granulomas in this context?

<p>T-cell mediated immune response to BCG antigens within the prostate. (B)</p> Signup and view all the answers

A 60-year-old male presents with dysuria, pelvic pain, and fever. Urinalysis reveals a high white blood cell count and the presence of bacteria. What is the most appropriate initial step in managing this patient?

<p>Obtain a urine culture and start empiric antibiotic therapy. (A)</p> Signup and view all the answers

When evaluating a patient with suspected chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), which of the following findings would be least consistent with the diagnosis?

<p>Marked and sustained fever with chills. (A)</p> Signup and view all the answers

A patient with granulomatous prostatitis secondary to BCG treatment for bladder cancer shows no improvement after antibiotic therapy. Which of the following is the most appropriate next step in management?

<p>Prescribe a course of corticosteroids to reduce inflammation. (D)</p> Signup and view all the answers

Flashcards

Prostatitis

Inflammation of the prostate gland, classified as bacterial (acute and chronic) or abacterial (chronic).

Acute Prostatitis

Presents with neutrophils in the glandular lumen and reactive glandular atypia with prominent nucleoli.

Chronic Prostatitis

Characterized by lymphocytes and plasma cells in the glandular lumen and stroma.

Granulomatous Prostatitis

Characterized by granulomatous inflammation with giant cells and plasma cells.

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Common infectious cause of prostatitis

A common infectious cause of prostatitis involves gram-negative rods and Enterococcus.

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Granulomatous prostatitis association

Granulomatous prostatitis can sometimes be seen after BCG therapy for bladder cancer.

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Elevated PSA cause

Acute prostatitis can sometimes be the cause of clinically elevated PSA.

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Study Notes

  • A vector function r maps a real number to a vector.

Definition

  • Two-dimensional vector function: r(t) = f(t)i + g(t)j = <f(t), g(t)>, where f and g are real functions.
  • Three-dimensional vector function: r(t) = f(t)i + g(t)j + h(t)k = <f(t), g(t), h(t)>, where f, g, and h are real functions.

Example

  • A helix can be represented by the vector function r(t) = cos t i + sin t j + t k.

Limit of a Vector Function

  • If r(t) = <f(t), g(t)>, then lim (t→a) r(t) = <lim (t→a) f(t), lim (t→a) g(t)>.
  • If r(t) = <f(t), g(t), h(t)>, then lim (t→a) r(t) = <lim (t→a) f(t), lim (t→a) g(t), lim (t→a) h(t)>, provided the component function limits exist.

Continuity

  • A vector function r is continuous at a if lim (t→a) r(t) = r(a).

Derivatives

  • For r(t) = <f(t), g(t)>, where f and g are differentiable, r'(t) = <f'(t), g'(t)>.
  • For r(t) = <f(t), g(t), h(t)>, where f, g, and h are differentiable, r'(t) = <f'(t), g'(t), h'(t)>.

Differentiation Rules

  • d/dt [u(t) + v(t)] = u'(t) + v'(t)
  • d/dt [c u(t)] = c u'(t)
  • d/dt [f(t) u(t)] = f'(t) u(t) + f(t) u'(t)
  • d/dt [u(t) â‹… v(t)] = u'(t) â‹… v(t) + u(t) â‹… v'(t)
  • d/dt [u(t) × v(t)] = u'(t) × v(t) + u(t) × v'(t)
  • d/dt [u(f(t))] = f'(t) u'(f(t))

Integrals

  • If r(t) = <f(t), g(t)>, then ∫(a to b) r(t) dt = <∫(a to b) f(t) dt, ∫(a to b) g(t) dt>.
  • If r(t) = <f(t), g(t), h(t)>, then ∫(a to b) r(t) dt = <∫(a to b) f(t) dt, ∫(a to b) g(t) dt, ∫(a to b) h(t) dt>.

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