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Questions and Answers
Which of the following are generic names of vasopressin?
Which of the following are generic names of vasopressin?
Which of the following is a brand name for vasopressin?
Which of the following is a brand name for vasopressin?
What drug class does vasopressin belong to?
What drug class does vasopressin belong to?
Antidiuretic hormones
What is one of the uses of vasopressin systemic?
What is one of the uses of vasopressin systemic?
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What is the description of vasopressin injection?
What is the description of vasopressin injection?
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From which gland is vasopressin released?
From which gland is vasopressin released?
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What is a physiologic action of vasopressin?
What is a physiologic action of vasopressin?
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How is vasopressin supplied?
How is vasopressin supplied?
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What are the main actions of vasopressin?
What are the main actions of vasopressin?
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Study Notes
Vasopressin Overview
- Generic name: vasopressin (pronounced VAY soe PRES in).
- Brand names include Vasostrict and Pitressin.
Drug Classification
- Classified as an antidiuretic hormone, also called arginine vasopressin.
- It functions as a nonadrenergic vasoconstrictor and vasopressor.
Mechanism and Physiologic Actions
- Synthesized in the hypothalamus and released from the posterior pituitary gland.
- Regulates water retention in kidneys by increasing water reabsorption.
- Acts through V1 and V2 receptors; V2 receptors mediate water conservation, while V1 receptors cause vasoconstriction.
- Increases permeability of kidney collecting ducts to water and can cause vasoconstriction, especially in cardiovascular smooth muscle.
Clinical Applications
- Used for various conditions including:
- Diabetes Insipidus
- Gastrointestinal hemorrhage
- Esophageal varices with bleeding
- Cardiac arrest conditions such as asystole, ventricular fibrillation, and ventricular tachycardia.
- Administered for abdominal distension before radiological procedures.
Pharmacology
- Antidiuretic effect usually lasts between 2 to 8 hours post-injection.
- Metabolized quickly with a plasma half-life of about 10 to 20 minutes.
- Up to 5% of the administered dose can be excreted unchanged in urine after 4 hours.
Preparation and Dosage Forms
- Available in 1 mL vials with 20 pressor units per mL for intramuscular, subcutaneous, and intravenous administration.
Additional Information
- Contains chlorobutanol as a preservative, with a pH adjustment made using glacial acetic acid or sodium hydroxide.
- Notable for its disulfide bridge structure and classification as a nine amino acid peptide.
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Description
Test your knowledge on Vasopressin with these flashcards. Learn about its generic and brand names, drug classifications, and therapeutic uses. Perfect for those studying pharmacology or related health sciences.
