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Questions and Answers
What is the class of Vasopressin?
What is the class of Vasopressin?
- Hormone
- Vasopressor
- Both A and B (correct)
- None of the above
What is the mechanism of action (MOA) of Vasopressin?
What is the mechanism of action (MOA) of Vasopressin?
Acts as a non-alpha-adrenergic vasoconstrictor through direct stimulation of smooth muscle receptors.
The duration of Vasopressin is typically _____ minutes.
The duration of Vasopressin is typically _____ minutes.
30-60
What is the generic name of Vasopressin?
What is the generic name of Vasopressin?
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What are the indications for using Vasopressin?
What are the indications for using Vasopressin?
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Vasopressin is contraindicated in patients with chronic nephritis.
Vasopressin is contraindicated in patients with chronic nephritis.
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List some common side effects of Vasopressin.
List some common side effects of Vasopressin.
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The adult dosage of Vasopressin for IV administration is _____ units.
The adult dosage of Vasopressin for IV administration is _____ units.
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Study Notes
Vasopressin Overview
- Vasopressin is classified as a hormone and vasopressor, primarily involved in regulating blood pressure.
Mechanism of Action (MOA)
- Acts as a non-alpha-adrenergic vasoconstrictor at higher doses.
- Stimulates smooth muscle receptors directly, influencing vascular tone.
- Can serve as an alternative to epinephrine in cardiopulmonary resuscitation (CPR).
Pharmacokinetics
- Onset and peak effects are variable, depending on individual responses.
- Duration of action ranges from 30 to 60 minutes.
- Half-life is between 20 to 30 minutes, indicating the time taken for the drug's effects to reduce by half.
Generic Name
- Under the brand name "Pitressin," it is widely recognized in the medical field.
Indications for Use
- Primarily indicated for increasing peripheral vascular resistance during CPR.
- Can be given when epinephrine is not effective or has already been administered.
Contraindications
- Contraindicated in individuals with chronic nephritis, ischemic heart disease, premature ventricular contractions (PVCs), and advanced arteriosclerosis.
- During CPR, typical contraindications may not apply, allowing for its use in critical situations.
Side Effects
- Common adverse effects include:
- Abdominal cramps
- Angina (chest pain)
- Asthma exacerbation
- Blanching of the skin
- Heart failure
- Hypertension (high blood pressure)
- Nausea
Dosage
- Adult dosage is 40 units administered intravenously as a single dose.
- Pediatric dosage and administration specifics for cardiac arrest are not detailed.
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