Questions and Answers
What is the class of Vasopressin?
What is the mechanism of action (MOA) of Vasopressin?
Acts as a non-alpha-adrenergic vasoconstrictor through direct stimulation of smooth muscle receptors.
The duration of Vasopressin is typically _____ minutes.
30-60
What is the generic name of Vasopressin?
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What are the indications for using Vasopressin?
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Vasopressin is contraindicated in patients with chronic nephritis.
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List some common side effects of Vasopressin.
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The adult dosage of Vasopressin for IV administration is _____ units.
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Study Notes
Vasopressin Overview
- Vasopressin is classified as a hormone and vasopressor, primarily involved in regulating blood pressure.
Mechanism of Action (MOA)
- Acts as a non-alpha-adrenergic vasoconstrictor at higher doses.
- Stimulates smooth muscle receptors directly, influencing vascular tone.
- Can serve as an alternative to epinephrine in cardiopulmonary resuscitation (CPR).
Pharmacokinetics
- Onset and peak effects are variable, depending on individual responses.
- Duration of action ranges from 30 to 60 minutes.
- Half-life is between 20 to 30 minutes, indicating the time taken for the drug's effects to reduce by half.
Generic Name
- Under the brand name "Pitressin," it is widely recognized in the medical field.
Indications for Use
- Primarily indicated for increasing peripheral vascular resistance during CPR.
- Can be given when epinephrine is not effective or has already been administered.
Contraindications
- Contraindicated in individuals with chronic nephritis, ischemic heart disease, premature ventricular contractions (PVCs), and advanced arteriosclerosis.
- During CPR, typical contraindications may not apply, allowing for its use in critical situations.
Side Effects
- Common adverse effects include:
- Abdominal cramps
- Angina (chest pain)
- Asthma exacerbation
- Blanching of the skin
- Heart failure
- Hypertension (high blood pressure)
- Nausea
Dosage
- Adult dosage is 40 units administered intravenously as a single dose.
- Pediatric dosage and administration specifics for cardiac arrest are not detailed.
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Description
This quiz focuses on vasopressin, a crucial hormone known for its vasoconstrictive properties. Each card covers different aspects including its mechanism of action and pharmacokinetics. Test your knowledge on this important substance used in critical medical situations.
