Variation and DNA Structure
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Questions and Answers

What primarily determines the sequence of amino acids in a protein?

  • The environmental conditions during translation.
  • The availability of tRNA molecules.
  • The shape of the ribosome.
  • The sequence of bases in a gene. (correct)

Which of the following is an example of discontinuous variation?

  • Human height.
  • Body mass in dogs.
  • Leaf length in trees.
  • ABO blood groups. (correct)

In a monohybrid cross, if both parents are heterozygous (Tt), what is the expected phenotypic ratio of the offspring, assuming complete dominance?

  • 1:2:1
  • 9:3:3:1
  • 1:1
  • 3:1 (correct)

What is the relationship between a gene and a protein?

<p>A gene codes for a protein. (B)</p> Signup and view all the answers

In genetics, what does the term 'homozygous' refer to?

<p>Having two identical alleles for a gene. (B)</p> Signup and view all the answers

If a plant with the genotype $I^AI^B$ is crossed with a plant with the genotype $I^AI^O$, what are the possible blood group phenotypes of their offspring?

<p>A, B, and AB only (A)</p> Signup and view all the answers

Which statement best describes the role of DNA in controlling cell function?

<p>DNA controls cell function by regulating protein production. (B)</p> Signup and view all the answers

A scientist observes a deviation from the expected phenotypic ratio in a genetic cross. What is the most likely explanation for this deviation?

<p>The sample size was too small. (C)</p> Signup and view all the answers

A mutation in a gene results in a protein with a significantly different shape. How might this altered shape affect the protein's function?

<p>It will likely impair or abolish the protein's function. (D)</p> Signup and view all the answers

Consider a hypothetical scenario where a newly discovered gene has three alleles: $A_1$, $A_2$, and $A_3$. $A_1$ exhibits complete dominance over $A_2$, $A_2$ exhibits complete dominance over $A_3$, and $A_1$ is lethal in the homozygous condition. What is the expected phenotypic ratio in a cross between two individuals with the genotype $A_2A_3$?

<p>All offspring will have the same phenotype. (B)</p> Signup and view all the answers

Which process leads to the evolution of a species over time?

<p>Natural selection (D)</p> Signup and view all the answers

What is the outcome of artificial selection?

<p>Organisms with traits deemed desirable by humans (B)</p> Signup and view all the answers

MRSA (methicillin-resistant Staphylococcus aureus) is an example of what?

<p>Antibiotic resistance in bacteria via natural selection (C)</p> Signup and view all the answers

Which of the following is NOT a source of genetic variation within a population?

<p>Cloning (C)</p> Signup and view all the answers

Which of the following best describes the role of competition in natural selection?

<p>It leads to a 'struggle for survival', where better-adapted individuals thrive. (B)</p> Signup and view all the answers

What is the most direct effect of ionizing radiation on genetic material?

<p>It increases the rate of mutation (B)</p> Signup and view all the answers

Which of the following is the most comprehensive definition of evolution?

<p>Changes in the inherited traits of a population over successive generations (B)</p> Signup and view all the answers

Considering the steps of artificial selection, how would a breeder MOST likely ensure the perpetuation of a novel, recessive trait that initially appears in only a few offspring?

<p>Selectively breed only those offspring that express the novel trait with each other over several generations. (C)</p> Signup and view all the answers

How does the reduced susceptibility of certain mosquito populations to specific insecticides exemplify natural selection?

<p>Mosquitoes with pre-existing genetic variations that confer resistance to the insecticide survive and reproduce at a higher rate. (B)</p> Signup and view all the answers

In a scenario where a population of plants is subjected to a rapidly changing climate that favors drought resistance, but also selects against larger seed size due to resource scarcity, what evolutionary trade-off is MOST likely to occur?

<p>Plants will evolve increased drought resistance at the expense of seed size, leading to smaller seeds that can still germinate under harsh conditions. (A)</p> Signup and view all the answers

Flashcards

Chromosome Mutation

Change in the number or structure of chromosomes.

Down's Syndrome

Having 47 chromosomes instead of the normal 46 due to a chromosome mutation.

Sources of Genetic Variation

Mutation, meiosis, random mating, and random fertilization.

Mutation Rate Increase

Increased by exposure to ionizing radiation and certain chemicals.

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Natural Selection

Process where species evolve over time; better-adapted individuals survive and reproduce.

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Evolution

Inherited features of a population change over time due to natural selection.

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Antibiotic Resistance

Bacteria that survive antibiotic exposure and reproduce, passing on resistance genes.

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Artificial Selection

Humans select organisms with desirable traits to breed.

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Steps of Artificial Selection

Select parents, cross them, select offspring, and repeat.

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Role of Artificial Selection

Producing high-yield crops and livestock with desirable traits.

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Variation

Differences between individuals of the same species.

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Continuous Variation

A range of phenotypes; influenced by genes and environment.

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Discontinuous Variation

Limited phenotypes with no intermediates; usually caused by genes alone.

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DNA

A molecule with two coiled strands in a double helix, containing the genetic code.

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Gene

A section of DNA that codes for a specific protein.

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Inheritance

Passing of genetic information from parents to offspring.

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Allele

An alternative form of a gene.

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Dominant Allele

The allele expressed when only one copy is present.

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Phenotype

The physical expression of a gene.

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Codominance

Both alleles are equally expressed in the phenotype.

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Study Notes

Variation

  • Variation is the differences between individuals of the same species.

Continuous Variation

  • Results in a range of phenotypes between two extremes.
  • Body length and body mass are examples
  • Genes and the environment causes it

Discontinuous Variation

  • Results in a limited number of phenotypes with no intermediates.
  • ABO blood groups, seed shape, and seed color in peas are examples.
  • Genes usually cause it alone

Investigating Variation

  • Involves the study and description of both continuous and discontinuous variation.

Structure of DNA

  • Two strands are coiled into a double helix.
  • Each strand is made of nucleotides.
  • Each nucleotide contains a base: Adenine (A), Thymine (T), Cytosine (C), and Guanine (G).
  • Bases pair up: A with T and C with G.
  • Bonds between base pairs hold the strands together.

Gene Definition

  • A length of DNA that codes for a protein.

DNA Function

  • Controls cell function by controlling protein production including enzymes.

Protein Synthesis

  • The sequence of bases in a gene determines the sequence of amino acids in a protein.
  • Different amino acid sequences give proteins different shapes.

Inheritance

  • Transmission of genetic information from one generation to the next.

Allele

  • An alternative form of a gene.

Key Terms

  • Dominant: Allele expressed in the phenotype, even if only one copy is present.
  • Recessive: Allele only expressed if two copies are present.
  • Phenotype: Physical expression of a gene.
  • Genotype: Genetic makeup of an organism.
  • Homozygous: Two identical alleles for a gene (e.g., TT or tt).
  • Heterozygous: Two different alleles for a gene (e.g., Tt).

Genetic Diagrams

  • Punnett squares are used to predict monohybrid cross outcomes.
  • Phenotypic ratios include 1:1 or 3:1

Observed vs. Expected Ratios

  • Differences occur due to small sample sizes (random chance).

Pure-Breeding

  • Two identical homozygous individuals breeding together produce pure breeding offspring

Codominance

  • Both alleles are expressed equally in the phenotype.
  • ABO blood groups (Iá´¬, Iá´®, Iº) have phenotypes A, B, AB, and O.

Sex Determination

  • Humans: XX (female), XY (male).

Gene Mutation

  • Random change in the base sequence of DNA.
  • Sickle cell anaemia is caused by a mutation in the hemoglobin gene.

Chromosome Mutation

  • Change in chromosome number or structure.
  • Down's syndrome involves 47 chromosomes instead of 46.

Sources of Genetic Variation

  • Mutation, meiosis, random mating, and random fertilisation.

Mutation Rate

  • Is increased by ionising radiation and some chemicals.

Natural Selection

  • The process by which species evolve over time.
  • Variation exists within populations.
  • Many offspring are produced.
  • Struggle for survival involves competition for resources.
  • Better adapted individuals survive and reproduce, passing on their alleles to the next generation.

Evolution

  • Inherited features of a population changes over time due to natural selection.

Antibiotic Resistance

  • Example: MRSA (methicillin-resistant Staphylococcus aureus).
  • Bacteria with resistance survive and reproduce, passing on resistance genes.

Artificial Selection (Selective Breeding)

  • Humans select organisms with desirable traits.
  • Steps include selecting parents with desirable features, crossing them to produce the next generation, and repeating over many generations with selection of offspring with desirable features.
  • Used to produce economically important plants (e.g., high-yield crops) and animals (e.g., livestock with desirable traits).

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Description

Explore variation within species, including continuous and discontinuous types, and the structure and function of DNA. Understand how DNA codes for proteins and controls cell function. Learn about the building blocks of DNA and base pairing rules.

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